SFH1 (YLR321C)


Gene profile

Gene name: SFH1
Reference locus (S288C): YLR321C
Gene biotype: protein_coding

Description: Chromatin structure-remodeling complex subunit SFH1; Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog; hSNF5 tumor suppressor ortholog

Top 10 interactors (score): RSC4 (0.999); RSC6 (0.999); ARP7 (0.999); STH1 (0.999); RSC8 (0.999); RSC2 (0.999); NPL6 (0.998); ARP9 (0.998); RSC9 (0.998); RSC3 (0.997); RTT102 (0.995); RSC58 (0.995); RSC1 (0.994); HTL1 (0.992); RSC30 (0.986); LDB7 (0.985); SNF2 (0.924); SWI3 (0.91); ARP4 (0.886); SNF12 (0.885)

Homologues (species, bitscore): SMARCB1 (Homo sapiens, 116.3); Smarcb1 (Mus musculus, 116.3); smarcb1b (Danio rerio, 117.1); smarcb1 (Xenopus tropicalis, 115.5); Snr1 (Drosophila melanogaster, 102.4); snfc-5 (Caenorhabditis elegans, 102.4); BSH (Arabidopsis thaliana, 76.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:725038-726318:- gene-YLR321C_AKU4011 rna-NM_001182210.1_AKU4011 cds-NP_013425.1_AKU4011 99.4 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:6364-7644:+ gene-YLR321C_BG1 rna-NM_001182210.1_BG1 cds-NP_013425.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:760871-762151:- gene-YLR321C_Bruggeman rna-NM_001182210.1_Bruggeman cds-NP_013425.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:759026-760306:- gene-YLR321C_CAT1 rna-NM_001182210.1_CAT1 cds-NP_013425.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:759954-761234:- gene-YLR321C_CBS1585 rna-NM_001182210.1_CBS1585 cds-NP_013425.1_CBS1585 99.4 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:744554-745834:- gene-YLR321C_CBS436 rna-NM_001182210.1_CBS436 cds-NP_013425.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:797909-799189:- gene-YLR321C_CBS6412 rna-NM_001182210.1_CBS6412 cds-NP_013425.1_CBS6412 99.4 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:760626-761906:- gene-YLR321C_CBS6413 rna-NM_001182210.1_CBS6413 cds-NP_013425.1_CBS6413 99.4 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:761198-762478:- gene-YLR321C_CENPK1137D rna-NM_001182210.1_CENPK1137D cds-NP_013425.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:718321-719601:- gene-YLR321C_EthanolRed rna-NM_001182210.1_EthanolRed cds-NP_013425.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:747522-748802:- gene-YLR321C_FaliES1 rna-NM_001182210.1_FaliES1 cds-NP_013425.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000296.1:19055-20335:+ gene-YLR321C_JAY291 rna-NM_001182210.1_JAY291 cds-NP_013425.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:760097-761377:- gene-YLR321C_MUCL30387 rna-NM_001182210.1_MUCL30387 cds-NP_013425.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:765683-766963:- gene-YLR321C_MUCL30388 rna-NM_001182210.1_MUCL30388 cds-NP_013425.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:761195-762475:- gene-YLR321C_MUCL39482 rna-NM_001182210.1_MUCL39482 cds-NP_013425.1_MUCL39482 99.4 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:756346-757626:- gene-YLR321C_MUCL42920 rna-NM_001182210.1_MUCL42920 cds-NP_013425.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:776558-777838:- gene-YLR321C_NCIM3186 rna-NM_001182210.1_NCIM3186 cds-NP_013425.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:770535-771815:- gene-YLR321C_NCYC1407 rna-NM_001182210.1_NCYC1407 cds-NP_013425.1_NCYC1407 99.4 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:758318-759598:- gene-YLR321C_PE2H3 rna-NM_001182210.1_PE2H3 cds-NP_013425.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:758062-759342:- gene-YLR321C_PE2H4 rna-NM_001182210.1_PE2H4 cds-NP_013425.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:776584-777864:- gene-YLR321C_S288C rna-NM_001182210.1_S288C cds-NP_013425.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000039.1:6445-7725:+ gene-YLR321C_SA1 rna-NM_001182210.1_SA1 cds-NP_013425.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:749414-750694:- gene-YLR321C_ThermosaccDry rna-NM_001182210.1_ThermosaccDry cds-NP_013425.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:761534-762814:- gene-YLR321C_VR1 rna-NM_001182210.1_VR1 cds-NP_013425.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:87827-89107:- gene-YLR321C_ZTW1 rna-NM_001182210.1_ZTW1 cds-NP_013425.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:735556-736839:- gene-YLR321C_Sparadoxus rna-NM_001182210.1_Sparadoxus cds-NP_013425.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files