Gene name: SFB3
Reference locus (S288C): YHR098C
Gene biotype: protein_coding
Description: SED5-binding protein 3; Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat; COPII coat is required for cargo selection during vesicle formation in ER to Golgi transport; scaffolding function of Lst1p required to generate vesicles that can accommodate difficult cargo proteins that include large oligomeric assemblies and asymmetrically distributed membrane proteins; homologous to Sec24p and Sfb2p; Belongs to the SEC23/SEC24 family. SEC24 subfamily
Top 10 interactors (score): SEC16 (0.999); SEC31 (0.999); NEL1 (0.999); SEC13 (0.999); SEC23 (0.999); SAR1 (0.998); SEC24 (0.994); SEC22 (0.974); SED5 (0.968); SFB2 (0.968); ERD2 (0.962); NIT2 (0.962); RBK1 (0.962); HNT2 (0.962); SEC61 (0.954); KAR2 (0.939); BET1 (0.936); COP1 (0.934); SIT4 (0.928); ADE1 (0.926)
Homologues (species, bitscore): SEC24C (Homo sapiens, 260.8); Sec24d (Mus musculus, 258.5); sec24c (Danio rerio, 283.9); Sec24c (Xenopus tropicalis, 266.9); Sec24CD (Drosophila melanogaster, 268.5); sec-24.1 (Caenorhabditis elegans, 253.8); ERMO2 (Arabidopsis thaliana, 284.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:286056-288845:- | gene-YHR098C_AKU4011 | rna-NM_001179228.1_AKU4011 | cds-NP_011966.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:229055-231844:+ | gene-YHR098C_BG1 | rna-NM_001179228.1_BG1 | cds-NP_011966.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:293351-296140:- | gene-YHR098C_Bruggeman | rna-NM_001179228.1_Bruggeman | cds-NP_011966.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:288501-291290:- | gene-YHR098C_CAT1 | rna-NM_001179228.1_CAT1 | cds-NP_011966.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:285085-287874:- | gene-YHR098C_CBS1585 | rna-NM_001179228.1_CBS1585 | cds-NP_011966.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:282447-285236:- | gene-YHR098C_CBS436 | rna-NM_001179228.1_CBS436 | cds-NP_011966.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:286916-289705:- | gene-YHR098C_CBS6412 | rna-NM_001179228.1_CBS6412 | cds-NP_011966.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:286109-288898:- | gene-YHR098C_CBS6413 | rna-NM_001179228.1_CBS6413 | cds-NP_011966.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:292316-295105:- | gene-YHR098C_CENPK1137D | rna-NM_001179228.1_CENPK1137D | cds-NP_011966.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:344969-347758:- | gene-YHR098C_EthanolRed | rna-NM_001179228.1_EthanolRed | cds-NP_011966.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:286457-289246:- | gene-YHR098C_FaliES1 | rna-NM_001179228.1_FaliES1 | cds-NP_011966.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000045.1:7041-9829:- | gene-YHR098C_JAY291 | rna-NM_001179228.1_JAY291 | cds-NP_011966.1_JAY291 | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:292829-295618:- | gene-YHR098C_MUCL30387 | rna-NM_001179228.1_MUCL30387 | cds-NP_011966.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:292733-295522:- | gene-YHR098C_MUCL30388 | rna-NM_001179228.1_MUCL30388 | cds-NP_011966.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:285422-288211:- | gene-YHR098C_MUCL39482 | rna-NM_001179228.1_MUCL39482 | cds-NP_011966.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:291676-294465:- | gene-YHR098C_MUCL42920 | rna-NM_001179228.1_MUCL42920 | cds-NP_011966.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:299027-301816:- | gene-YHR098C_NCIM3186 | rna-NM_001179228.1_NCIM3186 | cds-NP_011966.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:287631-290420:- | gene-YHR098C_NCYC1407 | rna-NM_001179228.1_NCYC1407 | cds-NP_011966.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:287076-289865:- | gene-YHR098C_PE2H3 | rna-NM_001179228.1_PE2H3 | cds-NP_011966.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:294503-297292:- | gene-YHR098C_PE2H4 | rna-NM_001179228.1_PE2H4 | cds-NP_011966.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:299145-301934:- | gene-YHR098C_S288C | rna-NM_001179228.1_S288C | cds-NP_011966.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:57042-59831:+ | gene-YHR098C_SA1 | rna-NM_001179228.1_SA1 | cds-NP_011966.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:287540-290329:- | gene-YHR098C_ThermosaccDry | rna-NM_001179228.1_ThermosaccDry | cds-NP_011966.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:295165-297954:- | gene-YHR098C_VR1 | rna-NM_001179228.1_VR1 | cds-NP_011966.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:278570-281359:- | gene-YHR098C_ZTW1 | rna-NM_001179228.1_ZTW1 | cds-NP_011966.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:284227-287022:- | gene-YHR098C_Sparadoxus | rna-NM_001179228.1_Sparadoxus | cds-NP_011966.1_Sparadoxus | 91.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |