SFB2 (YNL049C)


Gene profile

Gene name: SFB2
Reference locus (S288C): YNL049C
Gene biotype: protein_coding

Description: SED5-binding protein 2; Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat; required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb3p; SFB2 has a paralog, SEC24, that arose from the whole genome duplication

Top 10 interactors (score): SEC13 (0.999); SEC23 (0.999); SEC31 (0.999); SAR1 (0.996); SEC16 (0.993); SEC22 (0.987); NEL1 (0.978); SED5 (0.97); SFB3 (0.968); SEC24 (0.944); BET1 (0.908); SAP155 (0.901); SAP190 (0.901); SAP185 (0.901); SAP4 (0.901); PHO81 (0.901); SIT4 (0.9); BOS1 (0.857); BET3 (0.839); ERV14 (0.837)

Homologues (species, bitscore): SEC24A (Homo sapiens, 422.5); Sec24a (Mus musculus, 424.9); sec24a (Danio rerio, 422.9); sec24b (Xenopus tropicalis, 405.2); Sec24AB (Drosophila melanogaster, 366.7); sec-24.2 (Caenorhabditis elegans, 379.0); ERMO2 (Arabidopsis thaliana, 361.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:523080-525710:- gene-YNL049C_AKU4011 rna-NM_001182888.1_AKU4011 cds-NP_014349.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:427041-429671:- gene-YNL049C_BG1 rna-NM_001182888.1_BG1 cds-NP_014349.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:540191-542821:- gene-YNL049C_Bruggeman rna-NM_001182888.1_Bruggeman cds-NP_014349.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:576753-579383:- gene-YNL049C_CAT1 rna-NM_001182888.1_CAT1 cds-NP_014349.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:523750-526380:- gene-YNL049C_CBS1585 rna-NM_001182888.1_CBS1585 cds-NP_014349.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:592001-594631:- gene-YNL049C_CBS436 rna-NM_001182888.1_CBS436 cds-NP_014349.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:518843-521473:- gene-YNL049C_CBS6412 rna-NM_001182888.1_CBS6412 cds-NP_014349.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:520161-522791:- gene-YNL049C_CBS6413 rna-NM_001182888.1_CBS6413 cds-NP_014349.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:528867-531498:- gene-YNL049C_CENPK1137D rna-NM_001182888.1_CENPK1137D cds-NP_014349.1_CENPK1137D 99.9 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:525902-528532:- gene-YNL049C_EthanolRed rna-NM_001182888.1_EthanolRed cds-NP_014349.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:516427-519057:- gene-YNL049C_FaliES1 rna-NM_001182888.1_FaliES1 cds-NP_014349.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000040.1:31471-34101:- gene-YNL049C_JAY291 rna-NM_001182888.1_JAY291 cds-NP_014349.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:536525-539155:- gene-YNL049C_MUCL30387 rna-NM_001182888.1_MUCL30387 cds-NP_014349.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:565945-568575:- gene-YNL049C_MUCL30388 rna-NM_001182888.1_MUCL30388 cds-NP_014349.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:521166-523796:- gene-YNL049C_MUCL39482 rna-NM_001182888.1_MUCL39482 cds-NP_014349.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:525238-527868:- gene-YNL049C_MUCL42920 rna-NM_001182888.1_MUCL42920 cds-NP_014349.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:535250-537880:- gene-YNL049C_NCIM3186 rna-NM_001182888.1_NCIM3186 cds-NP_014349.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:523218-525848:- gene-YNL049C_NCYC1407 rna-NM_001182888.1_NCYC1407 cds-NP_014349.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:526388-529018:- gene-YNL049C_PE2H3 rna-NM_001182888.1_PE2H3 cds-NP_014349.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:521463-524093:- gene-YNL049C_PE2H4 rna-NM_001182888.1_PE2H4 cds-NP_014349.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:535281-537911:- gene-YNL049C_S288C rna-NM_001182888.1_S288C cds-NP_014349.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:114312-116942:- gene-YNL049C_SA1 rna-NM_001182888.1_SA1 cds-NP_014349.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:517302-519932:- gene-YNL049C_ThermosaccDry rna-NM_001182888.1_ThermosaccDry cds-NP_014349.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:536349-538979:- gene-YNL049C_VR1 rna-NM_001182888.1_VR1 cds-NP_014349.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:426623-429253:- gene-YNL049C_ZTW1 rna-NM_001182888.1_ZTW1 cds-NP_014349.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:532551-535187:- gene-YNL049C_Sparadoxus rna-NM_001182888.1_Sparadoxus cds-NP_014349.1_Sparadoxus 89.4 99.9 Verified 1 1 1 False True False False False

Additional files