Gene name: SFB2
Reference locus (S288C): YNL049C
Gene biotype: protein_coding
Description: SED5-binding protein 2; Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat; required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb3p; SFB2 has a paralog, SEC24, that arose from the whole genome duplication
Top 10 interactors (score): SEC13 (0.999); SEC23 (0.999); SEC31 (0.999); SAR1 (0.996); SEC16 (0.993); SEC22 (0.987); NEL1 (0.978); SED5 (0.97); SFB3 (0.968); SEC24 (0.944); BET1 (0.908); SAP155 (0.901); SAP190 (0.901); SAP185 (0.901); SAP4 (0.901); PHO81 (0.901); SIT4 (0.9); BOS1 (0.857); BET3 (0.839); ERV14 (0.837)
Homologues (species, bitscore): SEC24A (Homo sapiens, 422.5); Sec24a (Mus musculus, 424.9); sec24a (Danio rerio, 422.9); sec24b (Xenopus tropicalis, 405.2); Sec24AB (Drosophila melanogaster, 366.7); sec-24.2 (Caenorhabditis elegans, 379.0); ERMO2 (Arabidopsis thaliana, 361.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:523080-525710:- | gene-YNL049C_AKU4011 | rna-NM_001182888.1_AKU4011 | cds-NP_014349.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:427041-429671:- | gene-YNL049C_BG1 | rna-NM_001182888.1_BG1 | cds-NP_014349.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:540191-542821:- | gene-YNL049C_Bruggeman | rna-NM_001182888.1_Bruggeman | cds-NP_014349.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:576753-579383:- | gene-YNL049C_CAT1 | rna-NM_001182888.1_CAT1 | cds-NP_014349.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:523750-526380:- | gene-YNL049C_CBS1585 | rna-NM_001182888.1_CBS1585 | cds-NP_014349.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:592001-594631:- | gene-YNL049C_CBS436 | rna-NM_001182888.1_CBS436 | cds-NP_014349.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:518843-521473:- | gene-YNL049C_CBS6412 | rna-NM_001182888.1_CBS6412 | cds-NP_014349.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:520161-522791:- | gene-YNL049C_CBS6413 | rna-NM_001182888.1_CBS6413 | cds-NP_014349.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:528867-531498:- | gene-YNL049C_CENPK1137D | rna-NM_001182888.1_CENPK1137D | cds-NP_014349.1_CENPK1137D | 99.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:525902-528532:- | gene-YNL049C_EthanolRed | rna-NM_001182888.1_EthanolRed | cds-NP_014349.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:516427-519057:- | gene-YNL049C_FaliES1 | rna-NM_001182888.1_FaliES1 | cds-NP_014349.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000040.1:31471-34101:- | gene-YNL049C_JAY291 | rna-NM_001182888.1_JAY291 | cds-NP_014349.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:536525-539155:- | gene-YNL049C_MUCL30387 | rna-NM_001182888.1_MUCL30387 | cds-NP_014349.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:565945-568575:- | gene-YNL049C_MUCL30388 | rna-NM_001182888.1_MUCL30388 | cds-NP_014349.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:521166-523796:- | gene-YNL049C_MUCL39482 | rna-NM_001182888.1_MUCL39482 | cds-NP_014349.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:525238-527868:- | gene-YNL049C_MUCL42920 | rna-NM_001182888.1_MUCL42920 | cds-NP_014349.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:535250-537880:- | gene-YNL049C_NCIM3186 | rna-NM_001182888.1_NCIM3186 | cds-NP_014349.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:523218-525848:- | gene-YNL049C_NCYC1407 | rna-NM_001182888.1_NCYC1407 | cds-NP_014349.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:526388-529018:- | gene-YNL049C_PE2H3 | rna-NM_001182888.1_PE2H3 | cds-NP_014349.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:521463-524093:- | gene-YNL049C_PE2H4 | rna-NM_001182888.1_PE2H4 | cds-NP_014349.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:535281-537911:- | gene-YNL049C_S288C | rna-NM_001182888.1_S288C | cds-NP_014349.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000024.1:114312-116942:- | gene-YNL049C_SA1 | rna-NM_001182888.1_SA1 | cds-NP_014349.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:517302-519932:- | gene-YNL049C_ThermosaccDry | rna-NM_001182888.1_ThermosaccDry | cds-NP_014349.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:536349-538979:- | gene-YNL049C_VR1 | rna-NM_001182888.1_VR1 | cds-NP_014349.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:426623-429253:- | gene-YNL049C_ZTW1 | rna-NM_001182888.1_ZTW1 | cds-NP_014349.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:532551-535187:- | gene-YNL049C_Sparadoxus | rna-NM_001182888.1_Sparadoxus | cds-NP_014349.1_Sparadoxus | 89.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |