Gene name: SFA1
Reference locus (S288C): YDL168W
Gene biotype: protein_coding
Description: Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase; formaldehyde dehydrogenase activity is glutathione-dependent; functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p; protein abundance increases in response to DNA replication stress; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily
Top 10 interactors (score): YJL068C (0.999); ADH4 (0.998); ARO10 (0.982); SAH1 (0.978); PDC6 (0.976); PDC5 (0.976); PDC1 (0.973); THI3 (0.973); ADO1 (0.962); ALD3 (0.886); ALD6 (0.873); ALD2 (0.865); HFD1 (0.858); ALD4 (0.85); LIH1 (0.837); ALD5 (0.822); GUD1 (0.821); ERR1 (0.802); FDH1 (0.782); ERR2 (0.763)
Homologues (species, bitscore): ADH5 (Homo sapiens, 482.3); Adh5 (Mus musculus, 483.4); adh5 (Danio rerio, 484.6); adh5 (Xenopus tropicalis, 466.1); Fdh (Drosophila melanogaster, 481.5); H24K24.3 (Caenorhabditis elegans, 452.2); HOT5 (Arabidopsis thaliana, 468.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:144021-145181:+ | gene-YDL168W_AKU4011 | rna-NM_001180228.1_AKU4011 | cds-NP_010113.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:404549-405709:- | gene-YDL168W_BG1 | rna-NM_001180228.1_BG1 | cds-NP_010113.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:160084-161244:+ | gene-YDL168W_Bruggeman | rna-NM_001180228.1_Bruggeman | cds-NP_010113.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:158392-159552:+ | gene-YDL168W_CAT1 | rna-NM_001180228.1_CAT1 | cds-NP_010113.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:142057-143217:+ | gene-YDL168W_CBS1585 | rna-NM_001180228.1_CBS1585 | cds-NP_010113.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:159017-160177:+ | gene-YDL168W_CBS436 | rna-NM_001180228.1_CBS436 | cds-NP_010113.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:141672-142832:+ | gene-YDL168W_CBS6412 | rna-NM_001180228.1_CBS6412 | cds-NP_010113.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:160483-161643:+ | gene-YDL168W_CBS6413 | rna-NM_001180228.1_CBS6413 | cds-NP_010113.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:158276-159436:+ | gene-YDL168W_CENPK1137D | rna-NM_001180228.1_CENPK1137D | cds-NP_010113.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:155483-156643:+ | gene-YDL168W_EthanolRed | rna-NM_001180228.1_EthanolRed | cds-NP_010113.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:160809-161969:+ | gene-YDL168W_FaliES1 | rna-NM_001180228.1_FaliES1 | cds-NP_010113.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:57594-58754:- | gene-YDL168W_JAY291 | rna-NM_001180228.1_JAY291 | cds-NP_010113.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:158379-159539:+ | gene-YDL168W_MUCL30387 | rna-NM_001180228.1_MUCL30387 | cds-NP_010113.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:150028-151188:+ | gene-YDL168W_MUCL30388 | rna-NM_001180228.1_MUCL30388 | cds-NP_010113.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:143200-144360:+ | gene-YDL168W_MUCL39482 | rna-NM_001180228.1_MUCL39482 | cds-NP_010113.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:25013-26173:- | gene-YDL168W_MUCL42920 | rna-NM_001180228.1_MUCL42920 | cds-NP_010113.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:159527-160687:+ | gene-YDL168W_NCIM3186 | rna-NM_001180228.1_NCIM3186 | cds-NP_010113.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:143140-144300:+ | gene-YDL168W_NCYC1407 | rna-NM_001180228.1_NCYC1407 | cds-NP_010113.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:150381-151541:+ | gene-YDL168W_PE2H3 | rna-NM_001180228.1_PE2H3 | cds-NP_010113.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:150385-151545:+ | gene-YDL168W_PE2H4 | rna-NM_001180228.1_PE2H4 | cds-NP_010113.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:159604-160764:+ | gene-YDL168W_S288C | rna-NM_001180228.1_S288C | cds-NP_010113.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:25154-26314:+ | gene-YDL168W_SA1 | rna-NM_001180228.1_SA1 | cds-NP_010113.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:160569-161729:+ | gene-YDL168W_ThermosaccDry | rna-NM_001180228.1_ThermosaccDry | cds-NP_010113.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:161152-162312:+ | gene-YDL168W_VR1 | rna-NM_001180228.1_VR1 | cds-NP_010113.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:158697-159857:+ | gene-YDL168W_ZTW1 | rna-NM_001180228.1_ZTW1 | cds-NP_010113.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:160849-162013:+ | gene-YDL168W_Sparadoxus | rna-NM_001180228.1_Sparadoxus | cds-NP_010113.1_Sparadoxus | 89.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |