SET3 (YKR029C)


Gene profile

Gene name: SET3
Reference locus (S288C): YKR029C
Gene biotype: protein_coding

Description: Defining member of the SET3 histone deacetylase complex; which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains; SET3 has a paralog, SET4, that arose from the whole genome duplication

Top 10 interactors (score): SNT1 (0.999); SIF2 (0.999); HOS4 (0.998); CPR1 (0.997); HOS2 (0.997); HST1 (0.976); SET1 (0.974); PHO23 (0.97); CTI6 (0.966); RXT2 (0.966); SIN3 (0.965); RPD3 (0.954); SDS3 (0.946); SAP30 (0.937); DEP1 (0.937); TOS4 (0.93); SWR1 (0.921); UME1 (0.916); RXT3 (0.912); UME6 (0.911)

Homologues (species, bitscore): ASH1L (Homo sapiens, 68.9); Kmt2e (Mus musculus, 67.4); kmt2e (Danio rerio, 72.8); kmt2e (Xenopus tropicalis, 67.0); upSET (Drosophila melanogaster, 78.2); set-9 (Caenorhabditis elegans, 53.1); MMD1 (Arabidopsis thaliana, 50.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:483240-485495:- gene-YKR029C_AKU4011 rna-NM_001179819.3_AKU4011 cds-NP_012954.3_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:157978-160233:+ gene-YKR029C_BG1 rna-NM_001179819.3_BG1 cds-NP_012954.3_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:505170-507425:- gene-YKR029C_Bruggeman rna-NM_001179819.3_Bruggeman cds-NP_012954.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:500667-502922:- gene-YKR029C_CAT1 rna-NM_001179819.3_CAT1 cds-NP_012954.3_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:495980-498235:- gene-YKR029C_CBS1585 rna-NM_001179819.3_CBS1585 cds-NP_012954.3_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:494821-497076:- gene-YKR029C_CBS436 rna-NM_001179819.3_CBS436 cds-NP_012954.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:480141-482396:- gene-YKR029C_CBS6412 rna-NM_001179819.3_CBS6412 cds-NP_012954.3_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:495809-498064:- gene-YKR029C_CBS6413 rna-NM_001179819.3_CBS6413 cds-NP_012954.3_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:497320-499575:- gene-YKR029C_CENPK1137D rna-NM_001179819.3_CENPK1137D cds-NP_012954.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:493708-495761:- gene-YKR029C_EthanolRed rna-NM_001179819.3_EthanolRed cds-NP_012954.3_EthanolRed 89.0 90.5 Unannotated 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:496639-498894:- gene-YKR029C_FaliES1 rna-NM_001179819.3_FaliES1 cds-NP_012954.3_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000077.1:54851-57106:+ gene-YKR029C_JAY291 rna-NM_001179819.3_JAY291 cds-NP_012954.3_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:505575-507830:- gene-YKR029C_MUCL30387 rna-NM_001179819.3_MUCL30387 cds-NP_012954.3_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:499930-502185:- gene-YKR029C_MUCL30388 rna-NM_001179819.3_MUCL30388 cds-NP_012954.3_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:495298-497553:- gene-YKR029C_MUCL39482 rna-NM_001179819.3_MUCL39482 cds-NP_012954.3_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:501333-503588:- gene-YKR029C_MUCL42920 rna-NM_001179819.3_MUCL42920 cds-NP_012954.3_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:497567-499822:- gene-YKR029C_NCIM3186 rna-NM_001179819.3_NCIM3186 cds-NP_012954.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:495504-497759:- gene-YKR029C_NCYC1407 rna-NM_001179819.3_NCYC1407 cds-NP_012954.3_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:520505-522760:- gene-YKR029C_PE2H3 rna-NM_001179819.3_PE2H3 cds-NP_012954.3_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:505228-507483:- gene-YKR029C_PE2H4 rna-NM_001179819.3_PE2H4 cds-NP_012954.3_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:497578-499833:- gene-YKR029C_S288C rna-NM_001179819.3_S288C cds-NP_012954.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000078.1:13916-16183:+ gene-YKR029C_SA1 rna-NM_001179819.3_SA1 cds-NP_012954.3_SA1 98.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:495892-498147:- gene-YKR029C_ThermosaccDry rna-NM_001179819.3_ThermosaccDry cds-NP_012954.3_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:495525-497780:- gene-YKR029C_VR1 rna-NM_001179819.3_VR1 cds-NP_012954.3_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:493939-496194:- gene-YKR029C_ZTW1 rna-NM_001179819.3_ZTW1 cds-NP_012954.3_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:519238-521481:- gene-YKR029C_Sparadoxus rna-NM_001179819.3_Sparadoxus cds-NP_012954.3_Sparadoxus 86.7 99.4 Verified 1 1 1 False True False False False

Additional files