SER1 (YOR184W)


Gene profile

Gene name: SER1
Reference locus (S288C): YOR184W
Gene biotype: protein_coding

Description: O-phospho-L-serine:2-oxoglutarate transaminase; 3-phosphoserine aminotransferase; catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p; protein abundance increases in response to DNA replication stress; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Top 10 interactors (score): SER33 (0.999); SER3 (0.999); SER2 (0.998); THR4 (0.974); MCY1 (0.947); SHM2 (0.921); CWC2 (0.9); GCV3 (0.853); MTD1 (0.836); GCV1 (0.825); ARG5,6 (0.805); PDX3 (0.802); ADE3 (0.798); GCV2 (0.778); ARO7 (0.774); ALT2 (0.769); TRP5 (0.744); SHM1 (0.742); MIS1 (0.737); HOM3 (0.736)

Homologues (species, bitscore): PSAT1 (Homo sapiens, 276.2); Psat1 (Mus musculus, 270.0); psat1 (Danio rerio, 289.7); psat1 (Xenopus tropicalis, 276.9); CG11899 (Drosophila melanogaster, 265.4); F26H9.5 (Caenorhabditis elegans, 260.0); AT2G17630 (Arabidopsis thaliana, 294.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:676685-677872:+ gene-YOR184W_AKU4011 rna-NM_001183603.3_AKU4011 cds-NP_014827.3_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:78742-79929:+ gene-YOR184W_BG1 rna-NM_001183603.3_BG1 cds-NP_014827.3_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:660698-661885:+ gene-YOR184W_Bruggeman rna-NM_001183603.3_Bruggeman cds-NP_014827.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:661872-663059:+ gene-YOR184W_CAT1 rna-NM_001183603.3_CAT1 cds-NP_014827.3_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:659674-660861:+ gene-YOR184W_CBS1585 rna-NM_001183603.3_CBS1585 cds-NP_014827.3_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:657793-658980:+ gene-YOR184W_CBS436 rna-NM_001183603.3_CBS436 cds-NP_014827.3_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:656790-657977:+ gene-YOR184W_CBS6412 rna-NM_001183603.3_CBS6412 cds-NP_014827.3_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:665431-666618:+ gene-YOR184W_CBS6413 rna-NM_001183603.3_CBS6413 cds-NP_014827.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:679107-680294:+ gene-YOR184W_CENPK1137D rna-NM_001183603.3_CENPK1137D cds-NP_014827.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:652662-653849:+ gene-YOR184W_EthanolRed rna-NM_001183603.3_EthanolRed cds-NP_014827.3_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:657735-658922:+ gene-YOR184W_FaliES1 rna-NM_001183603.3_FaliES1 cds-NP_014827.3_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000038.1:18618-19805:- gene-YOR184W_JAY291 rna-NM_001183603.3_JAY291 cds-NP_014827.3_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:665503-666690:+ gene-YOR184W_MUCL30387 rna-NM_001183603.3_MUCL30387 cds-NP_014827.3_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:672919-674106:+ gene-YOR184W_MUCL30388 rna-NM_001183603.3_MUCL30388 cds-NP_014827.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:667004-668191:+ gene-YOR184W_MUCL39482 rna-NM_001183603.3_MUCL39482 cds-NP_014827.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:676390-677577:+ gene-YOR184W_MUCL42920 rna-NM_001183603.3_MUCL42920 cds-NP_014827.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:679246-680433:+ gene-YOR184W_NCIM3186 rna-NM_001183603.3_NCIM3186 cds-NP_014827.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:667101-668288:+ gene-YOR184W_NCYC1407 rna-NM_001183603.3_NCYC1407 cds-NP_014827.3_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:665926-667113:+ gene-YOR184W_PE2H3 rna-NM_001183603.3_PE2H3 cds-NP_014827.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:676303-677490:+ gene-YOR184W_PE2H4 rna-NM_001183603.3_PE2H4 cds-NP_014827.3_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:679357-680544:+ gene-YOR184W_S288C rna-NM_001183603.3_S288C cds-NP_014827.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:95922-97109:+ gene-YOR184W_SA1 rna-NM_001183603.3_SA1 cds-NP_014827.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:656919-658106:+ gene-YOR184W_ThermosaccDry rna-NM_001183603.3_ThermosaccDry cds-NP_014827.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:720955-722142:+ gene-YOR184W_VR1 rna-NM_001183603.3_VR1 cds-NP_014827.3_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:390324-391511:+ gene-YOR184W_ZTW1 rna-NM_001183603.3_ZTW1 cds-NP_014827.3_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:662542-663729:+ gene-YOR184W_Sparadoxus rna-NM_001183603.3_Sparadoxus cds-NP_014827.3_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files