SEN34 (YAR008W)


Gene profile

Gene name: SEN34
Reference locus (S288C): YAR008W
Gene biotype: protein_coding

Description: Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease (Sen complex) is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease

Top 10 interactors (score): SEN2 (0.999); SEN54 (0.999); SEN15 (0.998); POP4 (0.966); POP1 (0.958); TRL1 (0.922); TPT1 (0.92); POP5 (0.909); POP8 (0.904); RPP1 (0.901); POP7 (0.9); POP3 (0.9); MUS81 (0.9); POP6 (0.9); RPM2 (0.9); MMS4 (0.9); RPR2 (0.9); MSR1 (0.887); PCH2 (0.771); TRM5 (0.698)

Homologues (species, bitscore): TSEN34 (Homo sapiens, 75.9); Tsen34 (Mus musculus, 81.3); tsen34 (Danio rerio, 85.1); tsen34 (Xenopus tropicalis, 95.1); CG33260 (Drosophila melanogaster, 54.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:144395-145222:+ gene-YAR008W_AKU4011 rna-NM_001178212.1_AKU4011 cds-NP_009405.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000103.1:6855-7682:+ gene-YAR008W_BG1 rna-NM_001178212.1_BG1 cds-NP_009405.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:159181-160008:+ gene-YAR008W_Bruggeman rna-NM_001178212.1_Bruggeman cds-NP_009405.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:146034-146861:+ gene-YAR008W_CAT1 rna-NM_001178212.1_CAT1 cds-NP_009405.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:157093-157920:+ gene-YAR008W_CBS1585 rna-NM_001178212.1_CBS1585 cds-NP_009405.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:157407-158234:+ gene-YAR008W_CBS436 rna-NM_001178212.1_CBS436 cds-NP_009405.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:769837-770664:+ gene-YAR008W_CBS6412 rna-NM_001178212.1_CBS6412 cds-NP_009405.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:155361-156188:+ gene-YAR008W_CBS6413 rna-NM_001178212.1_CBS6413 cds-NP_009405.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:158872-159699:+ gene-YAR008W_CENPK1137D rna-NM_001178212.1_CENPK1137D cds-NP_009405.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:144951-145778:+ gene-YAR008W_EthanolRed rna-NM_001178212.1_EthanolRed cds-NP_009405.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:160612-161439:+ gene-YAR008W_FaliES1 rna-NM_001178212.1_FaliES1 cds-NP_009405.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000248.1:17981-18808:+ gene-YAR008W_JAY291 rna-NM_001178212.1_JAY291 cds-NP_009405.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:160948-161775:+ gene-YAR008W_MUCL30387 rna-NM_001178212.1_MUCL30387 cds-NP_009405.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:157599-158426:+ gene-YAR008W_MUCL30388 rna-NM_001178212.1_MUCL30388 cds-NP_009405.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:156349-157176:+ gene-YAR008W_MUCL39482 rna-NM_001178212.1_MUCL39482 cds-NP_009405.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:158748-159575:+ gene-YAR008W_MUCL42920 rna-NM_001178212.1_MUCL42920 cds-NP_009405.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:158843-159670:+ gene-YAR008W_NCIM3186 rna-NM_001178212.1_NCIM3186 cds-NP_009405.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:143759-144586:+ gene-YAR008W_NCYC1407 rna-NM_001178212.1_NCYC1407 cds-NP_009405.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:145680-146507:+ gene-YAR008W_PE2H3 rna-NM_001178212.1_PE2H3 cds-NP_009405.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:145399-146226:+ gene-YAR008W_PE2H4 rna-NM_001178212.1_PE2H4 cds-NP_009405.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:158966-159793:+ gene-YAR008W_S288C rna-NM_001178212.1_S288C cds-NP_009405.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000100.1:17698-18525:+ gene-YAR008W_SA1 rna-NM_001178212.1_SA1 cds-NP_009405.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:159617-160444:+ gene-YAR008W_ThermosaccDry rna-NM_001178212.1_ThermosaccDry cds-NP_009405.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:164171-164998:+ gene-YAR008W_VR1 rna-NM_001178212.1_VR1 cds-NP_009405.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:131440-132267:+ gene-YAR008W_ZTW1 rna-NM_001178212.1_ZTW1 cds-NP_009405.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:149066-149887:+ gene-YAR008W_Sparadoxus rna-NM_001178212.1_Sparadoxus cds-NP_009405.1_Sparadoxus 91.0 99.2 Verified 1 1 1 False True False False False

Additional files