Gene name: SEN2
Reference locus (S288C): YLR105C
Gene biotype: protein_coding
Description: Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease (Sen complex) is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease;
Top 10 interactors (score): SEN34 (0.999); SEN54 (0.999); SEN15 (0.998); RPR2 (0.968); POP4 (0.961); POP6 (0.959); POP1 (0.955); TRL1 (0.92); POP5 (0.907); POP7 (0.9); POP3 (0.9); RPM2 (0.9); POP8 (0.9); MMS4 (0.9); MUS81 (0.9); RPP1 (0.9); TPT1 (0.896); SEN1 (0.877); PCH2 (0.75); PMD1 (0.711)
Homologues (species, bitscore): TSEN2 (Homo sapiens, 78.2); Tsen2 (Mus musculus, 88.6); tsen2 (Danio rerio, 89.0); tsen2 (Xenopus tropicalis, 82.0); CG31812 (Drosophila melanogaster, 57.8); At3g45590 (Arabidopsis thaliana, 67.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:329551-330684:- | gene-YLR105C_AKU4011 | rna-NM_001181992.1_AKU4011 | cds-NP_013206.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:292727-293860:- | gene-YLR105C_BG1 | rna-NM_001181992.1_BG1 | cds-NP_013206.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:339400-340533:- | gene-YLR105C_Bruggeman | rna-NM_001181992.1_Bruggeman | cds-NP_013206.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:339748-340881:- | gene-YLR105C_CAT1 | rna-NM_001181992.1_CAT1 | cds-NP_013206.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:336693-337826:- | gene-YLR105C_CBS1585 | rna-NM_001181992.1_CBS1585 | cds-NP_013206.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:327256-328389:- | gene-YLR105C_CBS436 | rna-NM_001181992.1_CBS436 | cds-NP_013206.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:335112-336245:- | gene-YLR105C_CBS6412 | rna-NM_001181992.1_CBS6412 | cds-NP_013206.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:336959-338092:- | gene-YLR105C_CBS6413 | rna-NM_001181992.1_CBS6413 | cds-NP_013206.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:332071-333204:- | gene-YLR105C_CENPK1137D | rna-NM_001181992.1_CENPK1137D | cds-NP_013206.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:329110-330243:- | gene-YLR105C_EthanolRed | rna-NM_001181992.1_EthanolRed | cds-NP_013206.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:328929-330062:- | gene-YLR105C_FaliES1 | rna-NM_001181992.1_FaliES1 | cds-NP_013206.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:103856-104989:- | gene-YLR105C_JAY291 | rna-NM_001181992.1_JAY291 | cds-NP_013206.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:336776-337909:- | gene-YLR105C_MUCL30387 | rna-NM_001181992.1_MUCL30387 | cds-NP_013206.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:344444-345577:- | gene-YLR105C_MUCL30388 | rna-NM_001181992.1_MUCL30388 | cds-NP_013206.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:337201-338334:- | gene-YLR105C_MUCL39482 | rna-NM_001181992.1_MUCL39482 | cds-NP_013206.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:337105-338238:- | gene-YLR105C_MUCL42920 | rna-NM_001181992.1_MUCL42920 | cds-NP_013206.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:347021-348154:- | gene-YLR105C_NCIM3186 | rna-NM_001181992.1_NCIM3186 | cds-NP_013206.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:329264-330397:- | gene-YLR105C_NCYC1407 | rna-NM_001181992.1_NCYC1407 | cds-NP_013206.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:335021-336154:- | gene-YLR105C_PE2H3 | rna-NM_001181992.1_PE2H3 | cds-NP_013206.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:334762-335895:- | gene-YLR105C_PE2H4 | rna-NM_001181992.1_PE2H4 | cds-NP_013206.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:347047-348180:- | gene-YLR105C_S288C | rna-NM_001181992.1_S288C | cds-NP_013206.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:25912-27045:+ | gene-YLR105C_SA1 | rna-NM_001181992.1_SA1 | cds-NP_013206.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:329102-330235:- | gene-YLR105C_ThermosaccDry | rna-NM_001181992.1_ThermosaccDry | cds-NP_013206.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:343262-344395:- | gene-YLR105C_VR1 | rna-NM_001181992.1_VR1 | cds-NP_013206.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:328526-329659:- | gene-YLR105C_ZTW1 | rna-NM_001181992.1_ZTW1 | cds-NP_013206.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:337291-338424:- | gene-YLR105C_Sparadoxus | rna-NM_001181992.1_Sparadoxus | cds-NP_013206.1_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |