Gene name: SEI1
Reference locus (S288C): YLR404W
Gene biotype: protein_coding
Description: Seipin involved in lipid droplet (LD) assembly; controls lipid particle morphology, number, and size; promotes initiation of LD formation on the ER; ensures that LDs bud from the ER towards the cytosolic side of the membrane; forms a complex with Ldb16p at ER-LD contact sites, stabilizing these sites; null mutants have localized accumulation of phosphatidic acid (PA) marker proteins; BSCL2, human homolog implicated in congenital lipodystrophy, complements yeast null mutant
Top 10 interactors (score): LDB16 (0.985); YFT2 (0.908); DGA1 (0.887); PET10 (0.836); SCS3 (0.822); PEX30 (0.755); ARE2 (0.75); LRO1 (0.749); PAH1 (0.747); FDH1 (0.747); YJL068C (0.744); NEM1 (0.713); TGL3 (0.711); SPO7 (0.705); DAS2 (0.696); LPP1 (0.694); ICE2 (0.68); DPP1 (0.674); PCT1 (0.627); TGL4 (0.616)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:878277-879134:+ | gene-YLR404W_AKU4011 | rna-NM_001182292.3_AKU4011 | cds-NP_013508.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:110421-111278:+ | gene-YLR404W_BG1 | rna-NM_001182292.3_BG1 | cds-NP_013508.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:916583-917440:+ | gene-YLR404W_Bruggeman | rna-NM_001182292.3_Bruggeman | cds-NP_013508.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:912107-912964:+ | gene-YLR404W_CAT1 | rna-NM_001182292.3_CAT1 | cds-NP_013508.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:913873-914730:+ | gene-YLR404W_CBS1585 | rna-NM_001182292.3_CBS1585 | cds-NP_013508.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:897512-898369:+ | gene-YLR404W_CBS436 | rna-NM_001182292.3_CBS436 | cds-NP_013508.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:949914-950771:+ | gene-YLR404W_CBS6412 | rna-NM_001182292.3_CBS6412 | cds-NP_013508.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:914164-915021:+ | gene-YLR404W_CBS6413 | rna-NM_001182292.3_CBS6413 | cds-NP_013508.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:913554-914411:+ | gene-YLR404W_CENPK1137D | rna-NM_001182292.3_CENPK1137D | cds-NP_013508.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:870820-871677:+ | gene-YLR404W_EthanolRed | rna-NM_001182292.3_EthanolRed | cds-NP_013508.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:900130-900987:+ | gene-YLR404W_FaliES1 | rna-NM_001182292.3_FaliES1 | cds-NP_013508.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000434.1:53290-54147:+ | gene-YLR404W_JAY291 | rna-NM_001182292.3_JAY291 | cds-NP_013508.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:915449-916306:+ | gene-YLR404W_MUCL30387 | rna-NM_001182292.3_MUCL30387 | cds-NP_013508.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:921547-922404:+ | gene-YLR404W_MUCL30388 | rna-NM_001182292.3_MUCL30388 | cds-NP_013508.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:915093-915950:+ | gene-YLR404W_MUCL39482 | rna-NM_001182292.3_MUCL39482 | cds-NP_013508.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:909749-910606:+ | gene-YLR404W_MUCL42920 | rna-NM_001182292.3_MUCL42920 | cds-NP_013508.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:928717-929574:+ | gene-YLR404W_NCIM3186 | rna-NM_001182292.3_NCIM3186 | cds-NP_013508.3_NCIM3186 | 96.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:924273-925130:+ | gene-YLR404W_NCYC1407 | rna-NM_001182292.3_NCYC1407 | cds-NP_013508.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:910671-911528:+ | gene-YLR404W_PE2H3 | rna-NM_001182292.3_PE2H3 | cds-NP_013508.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:910415-911272:+ | gene-YLR404W_PE2H4 | rna-NM_001182292.3_PE2H4 | cds-NP_013508.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:928743-929600:+ | gene-YLR404W_S288C | rna-NM_001182292.3_S288C | cds-NP_013508.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:119088-119945:- | gene-YLR404W_SA1 | rna-NM_001182292.3_SA1 | cds-NP_013508.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:903209-904066:+ | gene-YLR404W_ThermosaccDry | rna-NM_001182292.3_ThermosaccDry | cds-NP_013508.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:915761-916618:+ | gene-YLR404W_VR1 | rna-NM_001182292.3_VR1 | cds-NP_013508.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:239927-240784:+ | gene-YLR404W_ZTW1 | rna-NM_001182292.3_ZTW1 | cds-NP_013508.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:888771-889628:+ | gene-YLR404W_Sparadoxus | rna-NM_001182292.3_Sparadoxus | cds-NP_013508.3_Sparadoxus | 88.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |