SEI1 (YLR404W)


Gene profile

Gene name: SEI1
Reference locus (S288C): YLR404W
Gene biotype: protein_coding

Description: Seipin involved in lipid droplet (LD) assembly; controls lipid particle morphology, number, and size; promotes initiation of LD formation on the ER; ensures that LDs bud from the ER towards the cytosolic side of the membrane; forms a complex with Ldb16p at ER-LD contact sites, stabilizing these sites; null mutants have localized accumulation of phosphatidic acid (PA) marker proteins; BSCL2, human homolog implicated in congenital lipodystrophy, complements yeast null mutant

Top 10 interactors (score): LDB16 (0.985); YFT2 (0.908); DGA1 (0.887); PET10 (0.836); SCS3 (0.822); PEX30 (0.755); ARE2 (0.75); LRO1 (0.749); PAH1 (0.747); FDH1 (0.747); YJL068C (0.744); NEM1 (0.713); TGL3 (0.711); SPO7 (0.705); DAS2 (0.696); LPP1 (0.694); ICE2 (0.68); DPP1 (0.674); PCT1 (0.627); TGL4 (0.616)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:878277-879134:+ gene-YLR404W_AKU4011 rna-NM_001182292.3_AKU4011 cds-NP_013508.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:110421-111278:+ gene-YLR404W_BG1 rna-NM_001182292.3_BG1 cds-NP_013508.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:916583-917440:+ gene-YLR404W_Bruggeman rna-NM_001182292.3_Bruggeman cds-NP_013508.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:912107-912964:+ gene-YLR404W_CAT1 rna-NM_001182292.3_CAT1 cds-NP_013508.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:913873-914730:+ gene-YLR404W_CBS1585 rna-NM_001182292.3_CBS1585 cds-NP_013508.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:897512-898369:+ gene-YLR404W_CBS436 rna-NM_001182292.3_CBS436 cds-NP_013508.3_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:949914-950771:+ gene-YLR404W_CBS6412 rna-NM_001182292.3_CBS6412 cds-NP_013508.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:914164-915021:+ gene-YLR404W_CBS6413 rna-NM_001182292.3_CBS6413 cds-NP_013508.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:913554-914411:+ gene-YLR404W_CENPK1137D rna-NM_001182292.3_CENPK1137D cds-NP_013508.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:870820-871677:+ gene-YLR404W_EthanolRed rna-NM_001182292.3_EthanolRed cds-NP_013508.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:900130-900987:+ gene-YLR404W_FaliES1 rna-NM_001182292.3_FaliES1 cds-NP_013508.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000434.1:53290-54147:+ gene-YLR404W_JAY291 rna-NM_001182292.3_JAY291 cds-NP_013508.3_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:915449-916306:+ gene-YLR404W_MUCL30387 rna-NM_001182292.3_MUCL30387 cds-NP_013508.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:921547-922404:+ gene-YLR404W_MUCL30388 rna-NM_001182292.3_MUCL30388 cds-NP_013508.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:915093-915950:+ gene-YLR404W_MUCL39482 rna-NM_001182292.3_MUCL39482 cds-NP_013508.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:909749-910606:+ gene-YLR404W_MUCL42920 rna-NM_001182292.3_MUCL42920 cds-NP_013508.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:928717-929574:+ gene-YLR404W_NCIM3186 rna-NM_001182292.3_NCIM3186 cds-NP_013508.3_NCIM3186 96.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:924273-925130:+ gene-YLR404W_NCYC1407 rna-NM_001182292.3_NCYC1407 cds-NP_013508.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:910671-911528:+ gene-YLR404W_PE2H3 rna-NM_001182292.3_PE2H3 cds-NP_013508.3_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:910415-911272:+ gene-YLR404W_PE2H4 rna-NM_001182292.3_PE2H4 cds-NP_013508.3_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:928743-929600:+ gene-YLR404W_S288C rna-NM_001182292.3_S288C cds-NP_013508.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:119088-119945:- gene-YLR404W_SA1 rna-NM_001182292.3_SA1 cds-NP_013508.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:903209-904066:+ gene-YLR404W_ThermosaccDry rna-NM_001182292.3_ThermosaccDry cds-NP_013508.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:915761-916618:+ gene-YLR404W_VR1 rna-NM_001182292.3_VR1 cds-NP_013508.3_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:239927-240784:+ gene-YLR404W_ZTW1 rna-NM_001182292.3_ZTW1 cds-NP_013508.3_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:888771-889628:+ gene-YLR404W_Sparadoxus rna-NM_001182292.3_Sparadoxus cds-NP_013508.3_Sparadoxus 88.4 100.0 Verified 1 1 1 False True False False False

Additional files