Gene name: SEH1
Reference locus (S288C): YGL100W
Gene biotype: protein_coding
Description: Nucleoporin SEH1; Subunit of the Nup84 nuclear pore and SEACAT subcomplexes; involved in nucleocytoplasmic transport and NPC biogenesis in the nuclear pore subcomplex; subunit of SEACAT, a subcomplex of the SEA complex that inhibits the TORC1 inhibitory role of SEACIT (Iml1p-Npr2p-Npr3p), a GAP for Gtr1p in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; human SEH1 homolog
Top 10 interactors (score): SEA4 (0.999); NUP133 (0.999); NUP85 (0.999); MTC5 (0.999); SEC13 (0.999); NUP120 (0.999); NUP100 (0.999); RTC1 (0.999); NUP116 (0.999); NUP84 (0.999); NUP145 (0.999); IML1 (0.998); NIC96 (0.996); MEX67 (0.996); NPR2 (0.995); NUP192 (0.993); NUP170 (0.991); NSP1 (0.991); GLE2 (0.989); NUP157 (0.985)
Homologues (species, bitscore): SEH1L (Homo sapiens, 205.7); Seh1l (Mus musculus, 207.2); seh1l (Danio rerio, 203.0); seh1l (Xenopus tropicalis, 206.8); Nup44A (Drosophila melanogaster, 187.6); npp-18 (Caenorhabditis elegans, 127.9); AT2G30050 (Arabidopsis thaliana, 117.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:316550-317599:+ | gene-YGL100W_AKU4011 | rna-NM_001180965.1_AKU4011 | cds-NP_011415.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:88117-89166:- | gene-YGL100W_BG1 | rna-NM_001180965.1_BG1 | cds-NP_011415.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:318704-319753:+ | gene-YGL100W_Bruggeman | rna-NM_001180965.1_Bruggeman | cds-NP_011415.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:314241-315290:+ | gene-YGL100W_CAT1 | rna-NM_001180965.1_CAT1 | cds-NP_011415.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:319874-320923:+ | gene-YGL100W_CBS1585 | rna-NM_001180965.1_CBS1585 | cds-NP_011415.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:314171-315220:+ | gene-YGL100W_CBS436 | rna-NM_001180965.1_CBS436 | cds-NP_011415.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:304567-305616:+ | gene-YGL100W_CBS6412 | rna-NM_001180965.1_CBS6412 | cds-NP_011415.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:314172-315221:+ | gene-YGL100W_CBS6413 | rna-NM_001180965.1_CBS6413 | cds-NP_011415.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:313415-314464:+ | gene-YGL100W_CENPK1137D | rna-NM_001180965.1_CENPK1137D | cds-NP_011415.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:305621-306670:+ | gene-YGL100W_EthanolRed | rna-NM_001180965.1_EthanolRed | cds-NP_011415.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:308176-309225:+ | gene-YGL100W_FaliES1 | rna-NM_001180965.1_FaliES1 | cds-NP_011415.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000046.1:37593-38642:- | gene-YGL100W_JAY291 | rna-NM_001180965.1_JAY291 | cds-NP_011415.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:315674-316723:+ | gene-YGL100W_MUCL30387 | rna-NM_001180965.1_MUCL30387 | cds-NP_011415.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:318758-319807:+ | gene-YGL100W_MUCL30388 | rna-NM_001180965.1_MUCL30388 | cds-NP_011415.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:316387-317436:+ | gene-YGL100W_MUCL39482 | rna-NM_001180965.1_MUCL39482 | cds-NP_011415.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:320337-321386:+ | gene-YGL100W_MUCL42920 | rna-NM_001180965.1_MUCL42920 | cds-NP_011415.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:313234-314283:+ | gene-YGL100W_NCIM3186 | rna-NM_001180965.1_NCIM3186 | cds-NP_011415.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:307877-308926:+ | gene-YGL100W_NCYC1407 | rna-NM_001180965.1_NCYC1407 | cds-NP_011415.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:309276-310325:+ | gene-YGL100W_PE2H3 | rna-NM_001180965.1_PE2H3 | cds-NP_011415.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:314274-315323:+ | gene-YGL100W_PE2H4 | rna-NM_001180965.1_PE2H4 | cds-NP_011415.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:313234-314283:+ | gene-YGL100W_S288C | rna-NM_001180965.1_S288C | cds-NP_011415.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000064.1:58019-59068:+ | gene-YGL100W_SA1 | rna-NM_001180965.1_SA1 | cds-NP_011415.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:308388-309437:+ | gene-YGL100W_ThermosaccDry | rna-NM_001180965.1_ThermosaccDry | cds-NP_011415.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:417992-419041:+ | gene-YGL100W_VR1 | rna-NM_001180965.1_VR1 | cds-NP_011415.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:305786-306835:+ | gene-YGL100W_ZTW1 | rna-NM_001180965.1_ZTW1 | cds-NP_011415.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:312161-313210:+ | gene-YGL100W_Sparadoxus | rna-NM_001180965.1_Sparadoxus | cds-NP_011415.1_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |