Gene name: SEC8
Reference locus (S288C): YPR055W
Gene biotype: protein_coding
Description: Essential 121 kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; involved in ER and Golgi inheritance in small buds; relocalizes away from bud neck upon DNA replication stress; Belongs to the SEC8 family
Top 10 interactors (score): SEC10 (0.999); SEC3 (0.999); SEC15 (0.999); SEC6 (0.999); SEC5 (0.999); EXO70 (0.999); EXO84 (0.999); SEC4 (0.999); CDC42 (0.991); SEC9 (0.982); RHO3 (0.973); MYO2 (0.967); SEC1 (0.967); SRO7 (0.962); RCY1 (0.955); SEC2 (0.945); MSS4 (0.91); ARF3 (0.87); ACT1 (0.847); BEM1 (0.842)
Homologues (species, bitscore): EXOC4 (Homo sapiens, 61.6); Exoc4 (Mus musculus, 61.6); exoc4 (Danio rerio, 77.4); ENSXETP00000035535 (Xenopus tropicalis, 50.8); SEC8 (Arabidopsis thaliana, 52.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:639341-642538:+ | gene-YPR055W_AKU4011 | rna-NM_001184152.1_AKU4011 | cds-NP_015380.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:255141-258338:- | gene-YPR055W_BG1 | rna-NM_001184152.1_BG1 | cds-NP_015380.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:717010-720207:+ | gene-YPR055W_Bruggeman | rna-NM_001184152.1_Bruggeman | cds-NP_015380.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:760464-763661:+ | gene-YPR055W_CAT1 | rna-NM_001184152.1_CAT1 | cds-NP_015380.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:643027-646224:+ | gene-YPR055W_CBS1585 | rna-NM_001184152.1_CBS1585 | cds-NP_015380.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:657406-660603:+ | gene-YPR055W_CBS436 | rna-NM_001184152.1_CBS436 | cds-NP_015380.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:646775-649972:+ | gene-YPR055W_CBS6412 | rna-NM_001184152.1_CBS6412 | cds-NP_015380.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:639976-643173:+ | gene-YPR055W_CBS6413 | rna-NM_001184152.1_CBS6413 | cds-NP_015380.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:667641-670838:+ | gene-YPR055W_CENPK1137D | rna-NM_001184152.1_CENPK1137D | cds-NP_015380.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:966532-969729:+ | gene-YPR055W_EthanolRed | rna-NM_001184152.1_EthanolRed | cds-NP_015380.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:645169-648366:+ | gene-YPR055W_FaliES1 | rna-NM_001184152.1_FaliES1 | cds-NP_015380.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:17127-20324:+ | gene-YPR055W_JAY291 | rna-NM_001184152.1_JAY291 | cds-NP_015380.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:658271-661468:+ | gene-YPR055W_MUCL30387 | rna-NM_001184152.1_MUCL30387 | cds-NP_015380.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:656975-660172:+ | gene-YPR055W_MUCL30388 | rna-NM_001184152.1_MUCL30388 | cds-NP_015380.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:636284-639481:+ | gene-YPR055W_MUCL39482 | rna-NM_001184152.1_MUCL39482 | cds-NP_015380.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:699112-702309:+ | gene-YPR055W_MUCL42920 | rna-NM_001184152.1_MUCL42920 | cds-NP_015380.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:667659-670856:+ | gene-YPR055W_NCIM3186 | rna-NM_001184152.1_NCIM3186 | cds-NP_015380.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:644214-647411:+ | gene-YPR055W_NCYC1407 | rna-NM_001184152.1_NCYC1407 | cds-NP_015380.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:650430-653627:+ | gene-YPR055W_PE2H3 | rna-NM_001184152.1_PE2H3 | cds-NP_015380.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:650078-653275:+ | gene-YPR055W_PE2H4 | rna-NM_001184152.1_PE2H4 | cds-NP_015380.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:667676-670873:+ | gene-YPR055W_S288C | rna-NM_001184152.1_S288C | cds-NP_015380.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:29818-33015:- | gene-YPR055W_SA1 | rna-NM_001184152.1_SA1 | cds-NP_015380.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:644944-648141:+ | gene-YPR055W_ThermosaccDry | rna-NM_001184152.1_ThermosaccDry | cds-NP_015380.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:661103-664300:+ | gene-YPR055W_VR1 | rna-NM_001184152.1_VR1 | cds-NP_015380.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:644175-647372:+ | gene-YPR055W_ZTW1 | rna-NM_001184152.1_ZTW1 | cds-NP_015380.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:644961-648158:+ | gene-YPR055W_Sparadoxus | rna-NM_001184152.1_Sparadoxus | cds-NP_015380.1_Sparadoxus | 89.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |