Gene name: SEC63
Reference locus (S288C): YOR254C
Gene biotype: protein_coding
Description: Protein translocation protein SEC63; Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec62p, Sec66p, and Sec72p
Top 10 interactors (score): SBH1 (0.999); SEC66 (0.999); SEC62 (0.999); SEC61 (0.999); SBH2 (0.999); KAR2 (0.999); SSS1 (0.999); SEC72 (0.999); LHS1 (0.996); CNE1 (0.989); SSH1 (0.987); WBP1 (0.975); PDI1 (0.963); ERJ5 (0.956); SRP102 (0.945); SEC23 (0.945); BRR2 (0.925); SFB3 (0.921); ERV29 (0.915); SRP54 (0.909)
Homologues (species, bitscore): SEC63 (Homo sapiens, 119.0); Sec63 (Mus musculus, 118.2); sec63 (Danio rerio, 129.4); sec63 (Xenopus tropicalis, 79.0); Sec63 (Drosophila melanogaster, 115.5); dnj-29 (Caenorhabditis elegans, 112.8); ATERDJ2B (Arabidopsis thaliana, 129.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:795803-797794:- | gene-YOR254C_AKU4011 | rna-NM_001183673.1_AKU4011 | cds-NP_014897.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:197840-199831:- | gene-YOR254C_BG1 | rna-NM_001183673.1_BG1 | cds-NP_014897.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:781271-783262:- | gene-YOR254C_Bruggeman | rna-NM_001183673.1_Bruggeman | cds-NP_014897.1_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:781918-783909:- | gene-YOR254C_CAT1 | rna-NM_001183673.1_CAT1 | cds-NP_014897.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:778792-780783:- | gene-YOR254C_CBS1585 | rna-NM_001183673.1_CBS1585 | cds-NP_014897.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:777484-779475:- | gene-YOR254C_CBS436 | rna-NM_001183673.1_CBS436 | cds-NP_014897.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:775911-777902:- | gene-YOR254C_CBS6412 | rna-NM_001183673.1_CBS6412 | cds-NP_014897.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:784552-786543:- | gene-YOR254C_CBS6413 | rna-NM_001183673.1_CBS6413 | cds-NP_014897.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:804793-806784:- | gene-YOR254C_CENPK1137D | rna-NM_001183673.1_CENPK1137D | cds-NP_014897.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:771919-773910:- | gene-YOR254C_EthanolRed | rna-NM_001183673.1_EthanolRed | cds-NP_014897.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:777318-779309:- | gene-YOR254C_FaliES1 | rna-NM_001183673.1_FaliES1 | cds-NP_014897.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:47521-49512:+ | gene-YOR254C_JAY291 | rna-NM_001183673.1_JAY291 | cds-NP_014897.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:785544-787535:- | gene-YOR254C_MUCL30387 | rna-NM_001183673.1_MUCL30387 | cds-NP_014897.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:792660-794651:- | gene-YOR254C_MUCL30388 | rna-NM_001183673.1_MUCL30388 | cds-NP_014897.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:786123-788114:- | gene-YOR254C_MUCL39482 | rna-NM_001183673.1_MUCL39482 | cds-NP_014897.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:795707-797698:- | gene-YOR254C_MUCL42920 | rna-NM_001183673.1_MUCL42920 | cds-NP_014897.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:804921-806912:- | gene-YOR254C_NCIM3186 | rna-NM_001183673.1_NCIM3186 | cds-NP_014897.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:786221-788212:- | gene-YOR254C_NCYC1407 | rna-NM_001183673.1_NCYC1407 | cds-NP_014897.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:785522-787513:- | gene-YOR254C_PE2H3 | rna-NM_001183673.1_PE2H3 | cds-NP_014897.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:795899-797890:- | gene-YOR254C_PE2H4 | rna-NM_001183673.1_PE2H4 | cds-NP_014897.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:805032-807023:- | gene-YOR254C_S288C | rna-NM_001183673.1_S288C | cds-NP_014897.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:215022-217013:- | gene-YOR254C_SA1 | rna-NM_001183673.1_SA1 | cds-NP_014897.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:776501-778492:- | gene-YOR254C_ThermosaccDry | rna-NM_001183673.1_ThermosaccDry | cds-NP_014897.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:839962-841953:- | gene-YOR254C_VR1 | rna-NM_001183673.1_VR1 | cds-NP_014897.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:509420-511411:- | gene-YOR254C_ZTW1 | rna-NM_001183673.1_ZTW1 | cds-NP_014897.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:782274-784265:- | gene-YOR254C_Sparadoxus | rna-NM_001183673.1_Sparadoxus | cds-NP_014897.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |