SEC62 (YPL094C)


Gene profile

Gene name: SEC62
Reference locus (S288C): YPL094C
Gene biotype: protein_coding

Description: Translocation protein SEC62; Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; cotranslationally N-acetylated by NatA; other members are Sec63p, Sec66p, and Sec72p

Top 10 interactors (score): SEC72 (0.999); SEC63 (0.999); SEC61 (0.999); SBH1 (0.999); SEC66 (0.999); SBH2 (0.998); SSS1 (0.998); KAR2 (0.994); CNE1 (0.97); PDI1 (0.955); SEC65 (0.954); SRP54 (0.936); BRR2 (0.927); SRP102 (0.901); ERV29 (0.901); DEG1 (0.896); LHS1 (0.891); SPC1 (0.882); YBR220C (0.863); SRP101 (0.853)

Homologues (species, bitscore): SEC62 (Homo sapiens, 95.5); Sec62 (Mus musculus, 96.3); sec62 (Danio rerio, 87.4); sec62 (Xenopus tropicalis, 93.6); Trp1 (Drosophila melanogaster, 85.1); C18E9.2 (Caenorhabditis elegans, 96.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:347481-348305:- gene-YPL094C_AKU4011 rna-NM_001183908.1_AKU4011 cds-NP_015231.2_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:553235-554059:- gene-YPL094C_BG1 rna-NM_001183908.1_BG1 cds-NP_015231.2_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:373487-374311:- gene-YPL094C_Bruggeman rna-NM_001183908.1_Bruggeman cds-NP_015231.2_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:370951-371775:- gene-YPL094C_CAT1 rna-NM_001183908.1_CAT1 cds-NP_015231.2_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:351554-352378:- gene-YPL094C_CBS1585 rna-NM_001183908.1_CBS1585 cds-NP_015231.2_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:366226-367050:- gene-YPL094C_CBS436 rna-NM_001183908.1_CBS436 cds-NP_015231.2_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:356223-357047:- gene-YPL094C_CBS6412 rna-NM_001183908.1_CBS6412 cds-NP_015231.2_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:348190-349014:- gene-YPL094C_CBS6413 rna-NM_001183908.1_CBS6413 cds-NP_015231.2_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:369787-370611:- gene-YPL094C_CENPK1137D rna-NM_001183908.1_CENPK1137D cds-NP_015231.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:346173-346997:- gene-YPL094C_EthanolRed rna-NM_001183908.1_EthanolRed cds-NP_015231.2_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:353765-354589:- gene-YPL094C_FaliES1 rna-NM_001183908.1_FaliES1 cds-NP_015231.2_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:11229-12053:+ gene-YPL094C_JAY291 rna-NM_001183908.1_JAY291 cds-NP_015231.2_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:364725-365549:- gene-YPL094C_MUCL30387 rna-NM_001183908.1_MUCL30387 cds-NP_015231.2_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:589243-590067:- gene-YPL094C_MUCL30388 rna-NM_001183908.1_MUCL30388 cds-NP_015231.2_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:344883-345707:- gene-YPL094C_MUCL39482 rna-NM_001183908.1_MUCL39482 cds-NP_015231.2_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:402571-403395:- gene-YPL094C_MUCL42920 rna-NM_001183908.1_MUCL42920 cds-NP_015231.2_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:369822-370646:- gene-YPL094C_NCIM3186 rna-NM_001183908.1_NCIM3186 cds-NP_015231.2_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:351336-352160:- gene-YPL094C_NCYC1407 rna-NM_001183908.1_NCYC1407 cds-NP_015231.2_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:358827-359651:- gene-YPL094C_PE2H3 rna-NM_001183908.1_PE2H3 cds-NP_015231.2_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:358450-359274:- gene-YPL094C_PE2H4 rna-NM_001183908.1_PE2H4 cds-NP_015231.2_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:369839-370663:- gene-YPL094C_S288C rna-NM_001183908.1_S288C cds-NP_015231.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:3016-3840:+ gene-YPL094C_SA1 rna-NM_001183908.1_SA1 cds-NP_015231.2_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:353563-354387:- gene-YPL094C_ThermosaccDry rna-NM_001183908.1_ThermosaccDry cds-NP_015231.2_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:368538-369362:- gene-YPL094C_VR1 rna-NM_001183908.1_VR1 cds-NP_015231.2_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:352884-353708:- gene-YPL094C_ZTW1 rna-NM_001183908.1_ZTW1 cds-NP_015231.2_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:354554-355378:- gene-YPL094C_Sparadoxus rna-NM_001183908.1_Sparadoxus cds-NP_015231.2_Sparadoxus 92.6 100.0 Verified 1 1 1 False True False False False

Additional files