Gene name: SEC6
Reference locus (S288C): YIL068C
Gene biotype: protein_coding
Description: Essential 88kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; anchors the assembled complex to sites of secretion; interacts with SM-like protein and SNARE regulator Sec1p and may recruit it to sites of secretion; binds to SNARE complexes binteracting with Sec9p
Top 10 interactors (score): SEC3 (0.999); SEC10 (0.999); SEC15 (0.999); SEC8 (0.999); SEC5 (0.999); EXO70 (0.999); EXO84 (0.999); SEC4 (0.998); SEC9 (0.998); SEC1 (0.996); CDC42 (0.959); SEC2 (0.958); SNC2 (0.957); RCY1 (0.945); MYO2 (0.927); SSO1 (0.899); SNC1 (0.898); COG4 (0.897); VPS53 (0.874); VPS33 (0.873)
Homologues (species, bitscore): EXOC3 (Homo sapiens, 79.3); Exoc3 (Mus musculus, 78.6); exoc3 (Danio rerio, 89.4); exoc3 (Xenopus tropicalis, 76.6); SEC6 (Arabidopsis thaliana, 75.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:229727-232144:- | gene-YIL068C_AKU4011 | rna-NM_001179418.1_AKU4011 | cds-NP_012196.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:91659-94076:- | gene-YIL068C_BG1 | rna-NM_001179418.1_BG1 | cds-NP_012196.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:235142-237559:- | gene-YIL068C_Bruggeman | rna-NM_001179418.1_Bruggeman | cds-NP_012196.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:225421-227838:- | gene-YIL068C_CAT1 | rna-NM_001179418.1_CAT1 | cds-NP_012196.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:229298-231715:- | gene-YIL068C_CBS1585 | rna-NM_001179418.1_CBS1585 | cds-NP_012196.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:225348-227765:- | gene-YIL068C_CBS436 | rna-NM_001179418.1_CBS436 | cds-NP_012196.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:226675-229092:- | gene-YIL068C_CBS6412 | rna-NM_001179418.1_CBS6412 | cds-NP_012196.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:221218-223635:- | gene-YIL068C_CBS6413 | rna-NM_001179418.1_CBS6413 | cds-NP_012196.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:224760-227177:- | gene-YIL068C_CENPK1137D | rna-NM_001179418.1_CENPK1137D | cds-NP_012196.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:214022-216439:- | gene-YIL068C_EthanolRed | rna-NM_001179418.1_EthanolRed | cds-NP_012196.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:230931-233348:- | gene-YIL068C_FaliES1 | rna-NM_001179418.1_FaliES1 | cds-NP_012196.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:64785-67202:+ | gene-YIL068C_JAY291 | rna-NM_001179418.1_JAY291 | cds-NP_012196.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:233361-235778:- | gene-YIL068C_MUCL30387 | rna-NM_001179418.1_MUCL30387 | cds-NP_012196.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:229970-232387:- | gene-YIL068C_MUCL30388 | rna-NM_001179418.1_MUCL30388 | cds-NP_012196.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:230145-232562:- | gene-YIL068C_MUCL39482 | rna-NM_001179418.1_MUCL39482 | cds-NP_012196.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:233509-235926:- | gene-YIL068C_MUCL42920 | rna-NM_001179418.1_MUCL42920 | cds-NP_012196.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:233057-235474:- | gene-YIL068C_NCIM3186 | rna-NM_001179418.1_NCIM3186 | cds-NP_012196.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:234422-236839:- | gene-YIL068C_NCYC1407 | rna-NM_001179418.1_NCYC1407 | cds-NP_012196.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:228403-230820:- | gene-YIL068C_PE2H3 | rna-NM_001179418.1_PE2H3 | cds-NP_012196.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:223118-225535:- | gene-YIL068C_PE2H4 | rna-NM_001179418.1_PE2H4 | cds-NP_012196.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:233057-235474:- | gene-YIL068C_S288C | rna-NM_001179418.1_S288C | cds-NP_012196.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:90359-92776:+ | gene-YIL068C_SA1 | rna-NM_001179418.1_SA1 | cds-NP_012196.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:229594-232011:- | gene-YIL068C_ThermosaccDry | rna-NM_001179418.1_ThermosaccDry | cds-NP_012196.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:227277-229694:- | gene-YIL068C_VR1 | rna-NM_001179418.1_VR1 | cds-NP_012196.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:203855-206272:- | gene-YIL068C_ZTW1 | rna-NM_001179418.1_ZTW1 | cds-NP_012196.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:227945-230362:- | gene-YIL068C_Sparadoxus | rna-NM_001179418.1_Sparadoxus | cds-NP_012196.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |