Gene name: SEC59
Reference locus (S288C): YMR013C
Gene biotype: protein_coding
Description: Dolichol kinase; catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation; Belongs to the polyprenol kinase family
Top 10 interactors (score): DPM1 (0.997); DFG10 (0.995); CAX4 (0.989); ALG5 (0.986); ALG7 (0.984); RER2 (0.934); SEC53 (0.88); NUS1 (0.876); ALG2 (0.863); ALG1 (0.853); LPP1 (0.816); ALG11 (0.815); PSA1 (0.779); PMT4 (0.741); ALG14 (0.722); YOL159C-A (0.717); EAF6 (0.711); PMT3 (0.707); PMT1 (0.694); MET7 (0.688)
Homologues (species, bitscore): DOLK (Homo sapiens, 132.1); Dolk (Mus musculus, 132.1); dolk (Danio rerio, 119.8); dolk (Xenopus tropicalis, 120.9); CG8311 (Drosophila melanogaster, 95.9); Y56A3A.36 (Caenorhabditis elegans, 74.3); AT3G45040 (Arabidopsis thaliana, 112.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:344801-346360:- | gene-YMR013C_AKU4011 | rna-NM_001182509.1_AKU4011 | cds-NP_013726.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:196512-198071:+ | gene-YMR013C_BG1 | rna-NM_001182509.1_BG1 | cds-NP_013726.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:284742-286301:- | gene-YMR013C_Bruggeman | rna-NM_001182509.1_Bruggeman | cds-NP_013726.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:287236-288795:- | gene-YMR013C_CAT1 | rna-NM_001182509.1_CAT1 | cds-NP_013726.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:277742-279301:- | gene-YMR013C_CBS1585 | rna-NM_001182509.1_CBS1585 | cds-NP_013726.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:283262-284821:- | gene-YMR013C_CBS436 | rna-NM_001182509.1_CBS436 | cds-NP_013726.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:391146-392705:- | gene-YMR013C_CBS6412 | rna-NM_001182509.1_CBS6412 | cds-NP_013726.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:276998-278557:- | gene-YMR013C_CBS6413 | rna-NM_001182509.1_CBS6413 | cds-NP_013726.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:289909-291468:- | gene-YMR013C_CENPK1137D | rna-NM_001182509.1_CENPK1137D | cds-NP_013726.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:277549-279108:- | gene-YMR013C_EthanolRed | rna-NM_001182509.1_EthanolRed | cds-NP_013726.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:280732-282291:- | gene-YMR013C_FaliES1 | rna-NM_001182509.1_FaliES1 | cds-NP_013726.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:154644-156203:+ | gene-YMR013C_JAY291 | rna-NM_001182509.1_JAY291 | cds-NP_013726.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:282453-284012:- | gene-YMR013C_MUCL30387 | rna-NM_001182509.1_MUCL30387 | cds-NP_013726.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:287128-288687:- | gene-YMR013C_MUCL30388 | rna-NM_001182509.1_MUCL30388 | cds-NP_013726.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:278027-279586:- | gene-YMR013C_MUCL39482 | rna-NM_001182509.1_MUCL39482 | cds-NP_013726.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:283812-285371:- | gene-YMR013C_MUCL42920 | rna-NM_001182509.1_MUCL42920 | cds-NP_013726.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:295133-296692:- | gene-YMR013C_NCIM3186 | rna-NM_001182509.1_NCIM3186 | cds-NP_013726.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:277944-279503:- | gene-YMR013C_NCYC1407 | rna-NM_001182509.1_NCYC1407 | cds-NP_013726.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:283870-285429:- | gene-YMR013C_PE2H3 | rna-NM_001182509.1_PE2H3 | cds-NP_013726.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:289965-291524:- | gene-YMR013C_PE2H4 | rna-NM_001182509.1_PE2H4 | cds-NP_013726.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:295179-296738:- | gene-YMR013C_S288C | rna-NM_001182509.1_S288C | cds-NP_013726.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:241531-243090:+ | gene-YMR013C_SA1 | rna-NM_001182509.1_SA1 | cds-NP_013726.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:277801-279360:- | gene-YMR013C_ThermosaccDry | rna-NM_001182509.1_ThermosaccDry | cds-NP_013726.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:281754-283313:- | gene-YMR013C_VR1 | rna-NM_001182509.1_VR1 | cds-NP_013726.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:256847-258406:- | gene-YMR013C_ZTW1 | rna-NM_001182509.1_ZTW1 | cds-NP_013726.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:290632-292191:- | gene-YMR013C_Sparadoxus | rna-NM_001182509.1_Sparadoxus | cds-NP_013726.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |