Gene name: SEC53
Reference locus (S288C): YFL045C
Gene biotype: protein_coding
Description: Phosphomannomutase; involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen; Belongs to the eukaryotic PMM family
Top 10 interactors (score): PMI40 (0.998); PSA1 (0.998); DPM1 (0.961); HXK2 (0.913); ALG2 (0.912); MAN2 (0.909); DSF1 (0.909); HXK1 (0.907); YLR446W (0.906); GLK1 (0.903); EMI2 (0.903); SEC59 (0.88); ALG7 (0.878); ALG1 (0.824); PGI1 (0.8); ARA2 (0.76); SEC31 (0.749); TPI1 (0.735); GAL10 (0.728); RFT1 (0.726)
Homologues (species, bitscore): PMM2 (Homo sapiens, 287.0); Pmm2 (Mus musculus, 282.3); pmm2 (Danio rerio, 295.0); pmm1 (Xenopus tropicalis, 283.1); CG10688 (Drosophila melanogaster, 283.9); F52B11.2 (Caenorhabditis elegans, 262.3); PMM (Arabidopsis thaliana, 284.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:39965-40729:- | gene-YFL045C_AKU4011 | rna-NM_001179922.1_AKU4011 | cds-NP_116609.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000182.1:29063-29827:+ | gene-YFL045C_BG1 | rna-NM_001179922.1_BG1 | cds-NP_116609.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:38343-39107:- | gene-YFL045C_Bruggeman | rna-NM_001179922.1_Bruggeman | cds-NP_116609.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:43732-44496:- | gene-YFL045C_CAT1 | rna-NM_001179922.1_CAT1 | cds-NP_116609.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:40642-41406:- | gene-YFL045C_CBS1585 | rna-NM_001179922.1_CBS1585 | cds-NP_116609.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:14277-15041:- | gene-YFL045C_CBS436 | rna-NM_001179922.1_CBS436 | cds-NP_116609.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:40882-41646:- | gene-YFL045C_CBS6412 | rna-NM_001179922.1_CBS6412 | cds-NP_116609.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:43043-43807:- | gene-YFL045C_CBS6413 | rna-NM_001179922.1_CBS6413 | cds-NP_116609.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:39954-40718:- | gene-YFL045C_CENPK1137D | rna-NM_001179922.1_CENPK1137D | cds-NP_116609.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:39309-40073:- | gene-YFL045C_EthanolRed | rna-NM_001179922.1_EthanolRed | cds-NP_116609.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:40517-41281:- | gene-YFL045C_FaliES1 | rna-NM_001179922.1_FaliES1 | cds-NP_116609.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:48974-49738:- | gene-YFL045C_JAY291 | rna-NM_001179922.1_JAY291 | cds-NP_116609.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:40932-41696:- | gene-YFL045C_MUCL30387 | rna-NM_001179922.1_MUCL30387 | cds-NP_116609.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:37956-38720:- | gene-YFL045C_MUCL30388 | rna-NM_001179922.1_MUCL30388 | cds-NP_116609.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:39158-39922:- | gene-YFL045C_MUCL39482 | rna-NM_001179922.1_MUCL39482 | cds-NP_116609.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:36862-37626:- | gene-YFL045C_MUCL42920 | rna-NM_001179922.1_MUCL42920 | cds-NP_116609.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:43627-44391:- | gene-YFL045C_NCIM3186 | rna-NM_001179922.1_NCIM3186 | cds-NP_116609.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:40235-40999:- | gene-YFL045C_NCYC1407 | rna-NM_001179922.1_NCYC1407 | cds-NP_116609.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:60128-60892:- | gene-YFL045C_PE2H3 | rna-NM_001179922.1_PE2H3 | cds-NP_116609.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:59679-60443:- | gene-YFL045C_PE2H4 | rna-NM_001179922.1_PE2H4 | cds-NP_116609.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:43628-44392:- | gene-YFL045C_S288C | rna-NM_001179922.1_S288C | cds-NP_116609.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:291240-292004:+ | gene-YFL045C_SA1 | rna-NM_001179922.1_SA1 | cds-NP_116609.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:39705-40469:- | gene-YFL045C_ThermosaccDry | rna-NM_001179922.1_ThermosaccDry | cds-NP_116609.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:48000-48764:- | gene-YFL045C_VR1 | rna-NM_001179922.1_VR1 | cds-NP_116609.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000012.1:25002-25766:- | gene-YFL045C_ZTW1 | rna-NM_001179922.1_ZTW1 | cds-NP_116609.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:64014-64778:- | gene-YFL045C_Sparadoxus | rna-NM_001179922.1_Sparadoxus | cds-NP_116609.1_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |