Gene name: SEC5
Reference locus (S288C): YDR166C
Gene biotype: protein_coding
Description: Essential 107kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; involved in assembly of the exocyst complex; required with Sec3p for ER inheritance where it promotes anchoring of the cortical ER at the bud tip; Belongs to the SEC5 family
Top 10 interactors (score): EXO84 (0.999); EXO70 (0.999); SEC6 (0.999); SEC8 (0.999); SEC15 (0.999); SEC10 (0.999); SEC3 (0.999); SEC4 (0.992); RCY1 (0.967); SEC1 (0.961); SEC9 (0.956); CDC42 (0.951); COG8 (0.916); SEC2 (0.914); MYO2 (0.906); SSO1 (0.866); RHO3 (0.858); ARF3 (0.853); YPT31 (0.846); VPS53 (0.836)
Homologues (species, bitscore): SEC5A (Arabidopsis thaliana, 56.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:757602-760517:- | gene-YDR166C_AKU4011 | rna-NM_001180473.3_AKU4011 | cds-NP_010450.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:366238-369153:+ | gene-YDR166C_BG1 | rna-NM_001180473.3_BG1 | cds-NP_010450.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:789099-792014:- | gene-YDR166C_Bruggeman | rna-NM_001180473.3_Bruggeman | cds-NP_010450.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:776374-779289:- | gene-YDR166C_CAT1 | rna-NM_001180473.3_CAT1 | cds-NP_010450.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:747969-750884:- | gene-YDR166C_CBS1585 | rna-NM_001180473.3_CBS1585 | cds-NP_010450.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:774162-777077:- | gene-YDR166C_CBS436 | rna-NM_001180473.3_CBS436 | cds-NP_010450.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:743419-746334:- | gene-YDR166C_CBS6412 | rna-NM_001180473.3_CBS6412 | cds-NP_010450.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:771867-774782:- | gene-YDR166C_CBS6413 | rna-NM_001180473.3_CBS6413 | cds-NP_010450.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:786968-789883:- | gene-YDR166C_CENPK1137D | rna-NM_001180473.3_CENPK1137D | cds-NP_010450.3_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:757428-760343:- | gene-YDR166C_EthanolRed | rna-NM_001180473.3_EthanolRed | cds-NP_010450.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:765640-768555:- | gene-YDR166C_FaliES1 | rna-NM_001180473.3_FaliES1 | cds-NP_010450.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000119.1:13707-16622:+ | gene-YDR166C_JAY291 | rna-NM_001180473.3_JAY291 | cds-NP_010450.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:774477-777392:- | gene-YDR166C_MUCL30387 | rna-NM_001180473.3_MUCL30387 | cds-NP_010450.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:762987-765902:- | gene-YDR166C_MUCL30388 | rna-NM_001180473.3_MUCL30388 | cds-NP_010450.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:749397-752312:- | gene-YDR166C_MUCL39482 | rna-NM_001180473.3_MUCL39482 | cds-NP_010450.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:687221-690136:- | gene-YDR166C_MUCL42920 | rna-NM_001180473.3_MUCL42920 | cds-NP_010450.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:786229-789144:- | gene-YDR166C_NCIM3186 | rna-NM_001180473.3_NCIM3186 | cds-NP_010450.3_NCIM3186 | 97.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:748800-751715:- | gene-YDR166C_NCYC1407 | rna-NM_001180473.3_NCYC1407 | cds-NP_010450.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:767994-770909:- | gene-YDR166C_PE2H3 | rna-NM_001180473.3_PE2H3 | cds-NP_010450.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:767299-770214:- | gene-YDR166C_PE2H4 | rna-NM_001180473.3_PE2H4 | cds-NP_010450.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:786306-789221:- | gene-YDR166C_S288C | rna-NM_001180473.3_S288C | cds-NP_010450.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:133505-136420:- | gene-YDR166C_SA1 | rna-NM_001180473.3_SA1 | cds-NP_010450.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:763775-766690:- | gene-YDR166C_ThermosaccDry | rna-NM_001180473.3_ThermosaccDry | cds-NP_010450.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:778763-781678:- | gene-YDR166C_VR1 | rna-NM_001180473.3_VR1 | cds-NP_010450.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:26526-29441:- | gene-YDR166C_ZTW1 | rna-NM_001180473.3_ZTW1 | cds-NP_010450.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:769976-772894:- | gene-YDR166C_Sparadoxus | rna-NM_001180473.3_Sparadoxus | cds-NP_010450.3_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |