Gene name: SEC4
Reference locus (S288C): YFL005W
Gene biotype: protein_coding
Description: Ras-related protein SEC4; Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
Top 10 interactors (score): MYO2 (0.999); SEC8 (0.999); SEC2 (0.999); SEC9 (0.999); SEC15 (0.999); GDI1 (0.999); SEC10 (0.998); SEC6 (0.998); EXO70 (0.997); DSS4 (0.997); SEC1 (0.997); YPT1 (0.996); SRO7 (0.992); SEC5 (0.992); SLY1 (0.99); MRS6 (0.99); RPN11 (0.988); RHO1 (0.987); EXO84 (0.984); SPO20 (0.984)
Homologues (species, bitscore): RAB8B (Homo sapiens, 230.3); Rab8b (Mus musculus, 230.3); rab8a (Danio rerio, 233.8); rab8b (Xenopus tropicalis, 232.6); Rab10 (Drosophila melanogaster, 220.7); rab-8 (Caenorhabditis elegans, 237.3); RABE1e (Arabidopsis thaliana, 237.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:126743-127390:+ | gene-YFL005W_AKU4011 | rna-NM_001179961.1_AKU4011 | cds-NP_116650.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000079.1:12468-13115:+ | gene-YFL005W_BG1 | rna-NM_001179961.1_BG1 | cds-NP_116650.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:126310-126957:+ | gene-YFL005W_Bruggeman | rna-NM_001179961.1_Bruggeman | cds-NP_116650.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:132297-132944:+ | gene-YFL005W_CAT1 | rna-NM_001179961.1_CAT1 | cds-NP_116650.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:127568-128215:+ | gene-YFL005W_CBS1585 | rna-NM_001179961.1_CBS1585 | cds-NP_116650.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:102240-102887:+ | gene-YFL005W_CBS436 | rna-NM_001179961.1_CBS436 | cds-NP_116650.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:127309-127956:+ | gene-YFL005W_CBS6412 | rna-NM_001179961.1_CBS6412 | cds-NP_116650.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:129819-130466:+ | gene-YFL005W_CBS6413 | rna-NM_001179961.1_CBS6413 | cds-NP_116650.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:126618-127265:+ | gene-YFL005W_CENPK1137D | rna-NM_001179961.1_CENPK1137D | cds-NP_116650.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:125729-126376:+ | gene-YFL005W_EthanolRed | rna-NM_001179961.1_EthanolRed | cds-NP_116650.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:127376-128023:+ | gene-YFL005W_FaliES1 | rna-NM_001179961.1_FaliES1 | cds-NP_116650.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000450.1:12383-13030:+ | gene-YFL005W_JAY291 | rna-NM_001179961.1_JAY291 | cds-NP_116650.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:127940-128587:+ | gene-YFL005W_MUCL30387 | rna-NM_001179961.1_MUCL30387 | cds-NP_116650.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:125913-126560:+ | gene-YFL005W_MUCL30388 | rna-NM_001179961.1_MUCL30388 | cds-NP_116650.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:126012-126659:+ | gene-YFL005W_MUCL39482 | rna-NM_001179961.1_MUCL39482 | cds-NP_116650.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:125276-125923:+ | gene-YFL005W_MUCL42920 | rna-NM_001179961.1_MUCL42920 | cds-NP_116650.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:130333-130980:+ | gene-YFL005W_NCIM3186 | rna-NM_001179961.1_NCIM3186 | cds-NP_116650.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:127027-127674:+ | gene-YFL005W_NCYC1407 | rna-NM_001179961.1_NCYC1407 | cds-NP_116650.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:146917-147564:+ | gene-YFL005W_PE2H3 | rna-NM_001179961.1_PE2H3 | cds-NP_116650.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:146465-147112:+ | gene-YFL005W_PE2H4 | rna-NM_001179961.1_PE2H4 | cds-NP_116650.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:130334-130981:+ | gene-YFL005W_S288C | rna-NM_001179961.1_S288C | cds-NP_116650.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:186457-187104:- | gene-YFL005W_SA1 | rna-NM_001179961.1_SA1 | cds-NP_116650.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:126536-127183:+ | gene-YFL005W_ThermosaccDry | rna-NM_001179961.1_ThermosaccDry | cds-NP_116650.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:136427-137074:+ | gene-YFL005W_VR1 | rna-NM_001179961.1_VR1 | cds-NP_116650.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:56985-57632:+ | gene-YFL005W_ZTW1 | rna-NM_001179961.1_ZTW1 | cds-NP_116650.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:151061-151708:+ | gene-YFL005W_Sparadoxus | rna-NM_001179961.1_Sparadoxus | cds-NP_116650.1_Sparadoxus | 94.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |