SEC27 (YGL137W)


Gene profile

Gene name: SEC27
Reference locus (S288C): YGL137W
Gene biotype: protein_coding

Description: Coatomer subunit beta; Essential beta'-coat protein of the COPI coatomer; involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP

Top 10 interactors (score): SEC28 (0.999); RET3 (0.999); RET2 (0.999); COP1 (0.999); SEC21 (0.999); SEC26 (0.999); ARF1 (0.978); SEC23 (0.974); SEC13 (0.968); GLO3 (0.958); SEC18 (0.958); BET1 (0.954); SEC31 (0.954); SEC22 (0.946); ARF2 (0.935); ERV25 (0.923); USO1 (0.918); ERD2 (0.916); UFE1 (0.906); SEC24 (0.904)

Homologues (species, bitscore): COPB2 (Homo sapiens, 790.4); Copb2 (Mus musculus, 790.0); copb2 (Danio rerio, 785.4); copb2 (Xenopus tropicalis, 783.5); beta'COP (Drosophila melanogaster, 744.2); copb-2 (Caenorhabditis elegans, 745.0); AT1G52360 (Arabidopsis thaliana, 763.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:252432-255301:+ gene-YGL137W_AKU4011 rna-NM_001181002.1_AKU4011 cds-NP_011378.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:149626-152495:- gene-YGL137W_BG1 rna-NM_001181002.1_BG1 cds-NP_011378.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:254884-257753:+ gene-YGL137W_Bruggeman rna-NM_001181002.1_Bruggeman cds-NP_011378.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:250472-253341:+ gene-YGL137W_CAT1 rna-NM_001181002.1_CAT1 cds-NP_011378.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:255814-258683:+ gene-YGL137W_CBS1585 rna-NM_001181002.1_CBS1585 cds-NP_011378.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:250424-253293:+ gene-YGL137W_CBS436 rna-NM_001181002.1_CBS436 cds-NP_011378.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:242024-244893:+ gene-YGL137W_CBS6412 rna-NM_001181002.1_CBS6412 cds-NP_011378.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:250370-253239:+ gene-YGL137W_CBS6413 rna-NM_001181002.1_CBS6413 cds-NP_011378.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:250128-252997:+ gene-YGL137W_CENPK1137D rna-NM_001181002.1_CENPK1137D cds-NP_011378.1_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:242604-245473:+ gene-YGL137W_EthanolRed rna-NM_001181002.1_EthanolRed cds-NP_011378.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:243850-246719:+ gene-YGL137W_FaliES1 rna-NM_001181002.1_FaliES1 cds-NP_011378.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000090.1:93676-96545:+ gene-YGL137W_JAY291 rna-NM_001181002.1_JAY291 cds-NP_011378.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:251854-254723:+ gene-YGL137W_MUCL30387 rna-NM_001181002.1_MUCL30387 cds-NP_011378.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:254972-257841:+ gene-YGL137W_MUCL30388 rna-NM_001181002.1_MUCL30388 cds-NP_011378.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:252595-255464:+ gene-YGL137W_MUCL39482 rna-NM_001181002.1_MUCL39482 cds-NP_011378.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:255846-258715:+ gene-YGL137W_MUCL42920 rna-NM_001181002.1_MUCL42920 cds-NP_011378.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:249869-252738:+ gene-YGL137W_NCIM3186 rna-NM_001181002.1_NCIM3186 cds-NP_011378.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:244086-246955:+ gene-YGL137W_NCYC1407 rna-NM_001181002.1_NCYC1407 cds-NP_011378.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:245975-248844:+ gene-YGL137W_PE2H3 rna-NM_001181002.1_PE2H3 cds-NP_011378.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:250973-253842:+ gene-YGL137W_PE2H4 rna-NM_001181002.1_PE2H4 cds-NP_011378.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:249869-252738:+ gene-YGL137W_S288C rna-NM_001181002.1_S288C cds-NP_011378.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000081.1:2009-4878:- gene-YGL137W_SA1 rna-NM_001181002.1_SA1 cds-NP_011378.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:244079-246948:+ gene-YGL137W_ThermosaccDry rna-NM_001181002.1_ThermosaccDry cds-NP_011378.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:250889-253758:+ gene-YGL137W_VR1 rna-NM_001181002.1_VR1 cds-NP_011378.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:242156-245025:+ gene-YGL137W_ZTW1 rna-NM_001181002.1_ZTW1 cds-NP_011378.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:248190-251094:+ gene-YGL137W_Sparadoxus rna-NM_001181002.1_Sparadoxus cds-NP_011378.1_Sparadoxus 91.0 99.8 Verified 1 1 1 False True False False False

Additional files