Gene name: SEC23
Reference locus (S288C): YPR181C
Gene biotype: protein_coding
Description: GTPase-activating protein, stimulates the GTPase activity of Sar1p; component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat, involved in ER to Golgi transport; substrate of Ubp3/Bre5 complex; ubiquitylated by Ub-ligase Rsp5p; proteasome-mediated degradation of Sec23p is regulated by Cdc48p
Top 10 interactors (score): SEC22 (0.999); SFB2 (0.999); SEC24 (0.999); SEC16 (0.999); YPT1 (0.999); SEC31 (0.999); SAR1 (0.999); SEC13 (0.999); SFB3 (0.999); BET3 (0.998); SEC21 (0.995); SEC61 (0.994); BET1 (0.993); SED5 (0.991); ERV29 (0.989); SEC26 (0.986); KAR2 (0.984); SEC12 (0.982); SEC27 (0.974); TRS33 (0.969)
Homologues (species, bitscore): SEC23A (Homo sapiens, 766.9); Sec23a (Mus musculus, 765.0); sec23b (Danio rerio, 767.7); sec23b (Xenopus tropicalis, 770.8); Sec23 (Drosophila melanogaster, 764.6); sec-23 (Caenorhabditis elegans, 707.2); AT1G05520 (Arabidopsis thaliana, 647.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:851636-853942:- | gene-YPR181C_AKU4011 | rna-NM_001184278.1_AKU4011 | cds-NP_015507.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:43767-46073:+ | gene-YPR181C_BG1 | rna-NM_001184278.1_BG1 | cds-NP_015507.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:932915-935221:- | gene-YPR181C_Bruggeman | rna-NM_001184278.1_Bruggeman | cds-NP_015507.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:974977-977283:- | gene-YPR181C_CAT1 | rna-NM_001184278.1_CAT1 | cds-NP_015507.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:856438-858744:- | gene-YPR181C_CBS1585 | rna-NM_001184278.1_CBS1585 | cds-NP_015507.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:869982-872288:- | gene-YPR181C_CBS436 | rna-NM_001184278.1_CBS436 | cds-NP_015507.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:858222-860528:- | gene-YPR181C_CBS6412 | rna-NM_001184278.1_CBS6412 | cds-NP_015507.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:853366-855672:- | gene-YPR181C_CBS6413 | rna-NM_001184278.1_CBS6413 | cds-NP_015507.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:897437-899743:- | gene-YPR181C_CENPK1137D | rna-NM_001184278.1_CENPK1137D | cds-NP_015507.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1173388-1175694:- | gene-YPR181C_EthanolRed | rna-NM_001184278.1_EthanolRed | cds-NP_015507.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:853461-855767:- | gene-YPR181C_FaliES1 | rna-NM_001184278.1_FaliES1 | cds-NP_015507.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000081.1:40768-43074:- | gene-YPR181C_JAY291 | rna-NM_001184278.1_JAY291 | cds-NP_015507.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:900152-902458:- | gene-YPR181C_MUCL30387 | rna-NM_001184278.1_MUCL30387 | cds-NP_015507.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:874281-876587:- | gene-YPR181C_MUCL30388 | rna-NM_001184278.1_MUCL30388 | cds-NP_015507.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:848638-850944:- | gene-YPR181C_MUCL39482 | rna-NM_001184278.1_MUCL39482 | cds-NP_015507.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:913109-915415:- | gene-YPR181C_MUCL42920 | rna-NM_001184278.1_MUCL42920 | cds-NP_015507.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:897344-899650:- | gene-YPR181C_NCIM3186 | rna-NM_001184278.1_NCIM3186 | cds-NP_015507.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:856999-859305:- | gene-YPR181C_NCYC1407 | rna-NM_001184278.1_NCYC1407 | cds-NP_015507.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:869292-871598:- | gene-YPR181C_PE2H3 | rna-NM_001184278.1_PE2H3 | cds-NP_015507.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:868940-871246:- | gene-YPR181C_PE2H4 | rna-NM_001184278.1_PE2H4 | cds-NP_015507.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:897361-899667:- | gene-YPR181C_S288C | rna-NM_001184278.1_S288C | cds-NP_015507.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:26143-28449:+ | gene-YPR181C_SA1 | rna-NM_001184278.1_SA1 | cds-NP_015507.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:853149-855455:- | gene-YPR181C_ThermosaccDry | rna-NM_001184278.1_ThermosaccDry | cds-NP_015507.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:880947-883253:- | gene-YPR181C_VR1 | rna-NM_001184278.1_VR1 | cds-NP_015507.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:855696-858002:- | gene-YPR181C_ZTW1 | rna-NM_001184278.1_ZTW1 | cds-NP_015507.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:857767-860073:- | gene-YPR181C_Sparadoxus | rna-NM_001184278.1_Sparadoxus | cds-NP_015507.1_Sparadoxus | 92.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |