SEC2 (YNL272C)


Gene profile

Gene name: SEC2
Reference locus (S288C): YNL272C
Gene biotype: protein_coding

Description: Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles; Belongs to the SEC2 family

Top 10 interactors (score): SEC4 (0.999); SEC15 (0.999); YPT32 (0.993); YPT31 (0.981); GDI1 (0.968); SEC6 (0.958); DSS4 (0.948); SEC10 (0.947); SEC8 (0.945); SEC9 (0.918); MRS6 (0.914); SEC5 (0.914); MYO2 (0.909); SEC1 (0.906); SEC3 (0.902); YPT11 (0.897); SMY1 (0.886); EXO70 (0.836); YPT1 (0.832); CDC42 (0.821)

Homologues (species, bitscore): RAB3IP (Homo sapiens, 52.4); rab3ip (Xenopus tropicalis, 52.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:120608-122887:- gene-YNL272C_AKU4011 rna-NM_001183110.1_AKU4011 cds-NP_014127.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:24491-26770:- gene-YNL272C_BG1 rna-NM_001183110.1_BG1 cds-NP_014127.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:130401-132680:- gene-YNL272C_Bruggeman rna-NM_001183110.1_Bruggeman cds-NP_014127.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:134110-136389:- gene-YNL272C_CAT1 rna-NM_001183110.1_CAT1 cds-NP_014127.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:120998-123277:- gene-YNL272C_CBS1585 rna-NM_001183110.1_CBS1585 cds-NP_014127.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:116080-118359:- gene-YNL272C_CBS436 rna-NM_001183110.1_CBS436 cds-NP_014127.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:117420-119699:- gene-YNL272C_CBS6412 rna-NM_001183110.1_CBS6412 cds-NP_014127.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:117699-119978:- gene-YNL272C_CBS6413 rna-NM_001183110.1_CBS6413 cds-NP_014127.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:120630-122909:- gene-YNL272C_CENPK1137D rna-NM_001183110.1_CENPK1137D cds-NP_014127.1_CENPK1137D 98.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:118230-120509:- gene-YNL272C_EthanolRed rna-NM_001183110.1_EthanolRed cds-NP_014127.1_EthanolRed 98.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:112967-115246:- gene-YNL272C_FaliES1 rna-NM_001183110.1_FaliES1 cds-NP_014127.1_FaliES1 98.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:24199-26478:- gene-YNL272C_JAY291 rna-NM_001183110.1_JAY291 cds-NP_014127.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:125943-128222:- gene-YNL272C_MUCL30387 rna-NM_001183110.1_MUCL30387 cds-NP_014127.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:124005-126284:- gene-YNL272C_MUCL30388 rna-NM_001183110.1_MUCL30388 cds-NP_014127.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:118488-120767:- gene-YNL272C_MUCL39482 rna-NM_001183110.1_MUCL39482 cds-NP_014127.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:120741-123020:- gene-YNL272C_MUCL42920 rna-NM_001183110.1_MUCL42920 cds-NP_014127.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:126774-129053:- gene-YNL272C_NCIM3186 rna-NM_001183110.1_NCIM3186 cds-NP_014127.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:120355-122634:- gene-YNL272C_NCYC1407 rna-NM_001183110.1_NCYC1407 cds-NP_014127.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:117535-119814:- gene-YNL272C_PE2H3 rna-NM_001183110.1_PE2H3 cds-NP_014127.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:116923-119202:- gene-YNL272C_PE2H4 rna-NM_001183110.1_PE2H4 cds-NP_014127.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:126805-129084:- gene-YNL272C_S288C rna-NM_001183110.1_S288C cds-NP_014127.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000034.1:24264-26543:- gene-YNL272C_SA1 rna-NM_001183110.1_SA1 cds-NP_014127.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:113824-116103:- gene-YNL272C_ThermosaccDry rna-NM_001183110.1_ThermosaccDry cds-NP_014127.1_ThermosaccDry 98.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:132733-135012:- gene-YNL272C_VR1 rna-NM_001183110.1_VR1 cds-NP_014127.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:24187-26466:- gene-YNL272C_ZTW1 rna-NM_001183110.1_ZTW1 cds-NP_014127.1_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:124080-126359:- gene-YNL272C_Sparadoxus rna-NM_001183110.1_Sparadoxus cds-NP_014127.1_Sparadoxus 88.6 99.8 Verified 1 1 1 False True False False False

Additional files