Gene name: SEC18
Reference locus (S288C): YBR080C
Gene biotype: protein_coding
Description: Vesicular-fusion protein SEC18; AAA ATPase and SNARE disassembly chaperone; required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian N-ethylmaleimide-sensitive factor (NSF)
Top 10 interactors (score): SEC17 (0.999); VAM3 (0.996); SLY1 (0.996); SEC22 (0.992); YKT6 (0.991); SEC1 (0.99); SED5 (0.988); SSO1 (0.986); SEC9 (0.985); VTI1 (0.983); SSO2 (0.981); UFE1 (0.976); NYV1 (0.973); BOS1 (0.972); BET1 (0.971); YPT7 (0.968); PRE8 (0.964); PEP12 (0.964); VAM7 (0.96); SEC27 (0.958)
Homologues (species, bitscore): NSF (Homo sapiens, 652.9); Nsf (Mus musculus, 656.4); nsfb (Danio rerio, 652.9); nsf (Xenopus tropicalis, 648.7); comt (Drosophila melanogaster, 613.2); nsf-1 (Caenorhabditis elegans, 586.3); NSF (Arabidopsis thaliana, 562.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:380989-383265:- | gene-YBR080C_AKU4011 | rna-NM_001178428.3_AKU4011 | cds-NP_009636.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:371978-374254:- | gene-YBR080C_BG1 | rna-NM_001178428.3_BG1 | cds-NP_009636.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:382225-384501:- | gene-YBR080C_Bruggeman | rna-NM_001178428.3_Bruggeman | cds-NP_009636.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:385544-387820:- | gene-YBR080C_CAT1 | rna-NM_001178428.3_CAT1 | cds-NP_009636.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:373273-375549:- | gene-YBR080C_CBS1585 | rna-NM_001178428.3_CBS1585 | cds-NP_009636.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:381382-383658:- | gene-YBR080C_CBS436 | rna-NM_001178428.3_CBS436 | cds-NP_009636.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:471503-473779:- | gene-YBR080C_CBS6412 | rna-NM_001178428.3_CBS6412 | cds-NP_009636.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:378413-380689:- | gene-YBR080C_CBS6413 | rna-NM_001178428.3_CBS6413 | cds-NP_009636.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:392372-394648:- | gene-YBR080C_CENPK1137D | rna-NM_001178428.3_CENPK1137D | cds-NP_009636.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:507780-510056:- | gene-YBR080C_EthanolRed | rna-NM_001178428.3_EthanolRed | cds-NP_009636.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:397063-399339:- | gene-YBR080C_FaliES1 | rna-NM_001178428.3_FaliES1 | cds-NP_009636.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000124.1:44990-47266:- | gene-YBR080C_JAY291 | rna-NM_001178428.3_JAY291 | cds-NP_009636.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:383379-385655:- | gene-YBR080C_MUCL30387 | rna-NM_001178428.3_MUCL30387 | cds-NP_009636.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:383409-385685:- | gene-YBR080C_MUCL30388 | rna-NM_001178428.3_MUCL30388 | cds-NP_009636.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:373265-375541:- | gene-YBR080C_MUCL39482 | rna-NM_001178428.3_MUCL39482 | cds-NP_009636.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:380479-382755:- | gene-YBR080C_MUCL42920 | rna-NM_001178428.3_MUCL42920 | cds-NP_009636.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:398411-400687:- | gene-YBR080C_NCIM3186 | rna-NM_001178428.3_NCIM3186 | cds-NP_009636.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:374197-376473:- | gene-YBR080C_NCYC1407 | rna-NM_001178428.3_NCYC1407 | cds-NP_009636.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:386440-388716:- | gene-YBR080C_PE2H3 | rna-NM_001178428.3_PE2H3 | cds-NP_009636.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:384116-386392:- | gene-YBR080C_PE2H4 | rna-NM_001178428.3_PE2H4 | cds-NP_009636.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:398614-400890:- | gene-YBR080C_S288C | rna-NM_001178428.3_S288C | cds-NP_009636.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:76628-78904:+ | gene-YBR080C_SA1 | rna-NM_001178428.3_SA1 | cds-NP_009636.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:396070-398346:- | gene-YBR080C_ThermosaccDry | rna-NM_001178428.3_ThermosaccDry | cds-NP_009636.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:378058-380334:- | gene-YBR080C_VR1 | rna-NM_001178428.3_VR1 | cds-NP_009636.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:371739-374015:- | gene-YBR080C_ZTW1 | rna-NM_001178428.3_ZTW1 | cds-NP_009636.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:408660-410936:- | gene-YBR080C_Sparadoxus | rna-NM_001178428.3_Sparadoxus | cds-NP_009636.3_Sparadoxus | 93.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |