Gene name: SEC17
Reference locus (S288C): YBL050W
Gene biotype: protein_coding
Description: Alpha-soluble NSF attachment protein; Alpha-SNAP cochaperone; SNARE-complex adaptor for Sec18 (NSF) during the disassembly of postfusion cis-SNARE complexes; stimulates the ATPase activity of Sec18p; peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; similar to mammalian alpha-SNAP
Top 10 interactors (score): VAM3 (0.999); SSO1 (0.999); VTI1 (0.999); SEC18 (0.999); VAM7 (0.999); SED5 (0.999); SEC9 (0.998); YKT6 (0.998); SEC22 (0.998); SSO2 (0.997); TLG2 (0.997); NYV1 (0.997); SLY1 (0.994); SPO20 (0.993); BET1 (0.988); SEC1 (0.988); BOS1 (0.987); UFE1 (0.98); SAR1 (0.979); TLG1 (0.979)
Homologues (species, bitscore): NAPA (Homo sapiens, 166.0); Napa (Mus musculus, 164.5); napba (Danio rerio, 165.2); napa (Xenopus tropicalis, 166.0); alphaSnap (Drosophila melanogaster, 156.4); snap-1 (Caenorhabditis elegans, 135.6); ASNAP2 (Arabidopsis thaliana, 156.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:118714-119708:+ | gene-YBL050W_AKU4011 | rna-NM_001178290.1_AKU4011 | cds-NP_009503.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:109555-110549:+ | gene-YBL050W_BG1 | rna-NM_001178290.1_BG1 | cds-NP_009503.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:119320-120314:+ | gene-YBL050W_Bruggeman | rna-NM_001178290.1_Bruggeman | cds-NP_009503.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:121954-122948:+ | gene-YBL050W_CAT1 | rna-NM_001178290.1_CAT1 | cds-NP_009503.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:111273-112267:+ | gene-YBL050W_CBS1585 | rna-NM_001178290.1_CBS1585 | cds-NP_009503.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:119779-120773:+ | gene-YBL050W_CBS436 | rna-NM_001178290.1_CBS436 | cds-NP_009503.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:109419-110413:+ | gene-YBL050W_CBS6412 | rna-NM_001178290.1_CBS6412 | cds-NP_009503.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:116850-117844:+ | gene-YBL050W_CBS6413 | rna-NM_001178290.1_CBS6413 | cds-NP_009503.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:118887-119881:+ | gene-YBL050W_CENPK1137D | rna-NM_001178290.1_CENPK1137D | cds-NP_009503.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:132704-133698:+ | gene-YBL050W_EthanolRed | rna-NM_001178290.1_EthanolRed | cds-NP_009503.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:133557-134551:+ | gene-YBL050W_FaliES1 | rna-NM_001178290.1_FaliES1 | cds-NP_009503.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000072.1:36174-37168:+ | gene-YBL050W_JAY291 | rna-NM_001178290.1_JAY291 | cds-NP_009503.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:118695-119689:+ | gene-YBL050W_MUCL30387 | rna-NM_001178290.1_MUCL30387 | cds-NP_009503.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:119970-120964:+ | gene-YBL050W_MUCL30388 | rna-NM_001178290.1_MUCL30388 | cds-NP_009503.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:111453-112447:+ | gene-YBL050W_MUCL39482 | rna-NM_001178290.1_MUCL39482 | cds-NP_009503.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:118287-119281:+ | gene-YBL050W_MUCL42920 | rna-NM_001178290.1_MUCL42920 | cds-NP_009503.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:124922-125916:+ | gene-YBL050W_NCIM3186 | rna-NM_001178290.1_NCIM3186 | cds-NP_009503.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:112599-113593:+ | gene-YBL050W_NCYC1407 | rna-NM_001178290.1_NCYC1407 | cds-NP_009503.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:118851-119845:+ | gene-YBL050W_PE2H3 | rna-NM_001178290.1_PE2H3 | cds-NP_009503.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:116495-117489:+ | gene-YBL050W_PE2H4 | rna-NM_001178290.1_PE2H4 | cds-NP_009503.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:125125-126119:+ | gene-YBL050W_S288C | rna-NM_001178290.1_S288C | cds-NP_009503.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000051.1:9706-10700:+ | gene-YBL050W_SA1 | rna-NM_001178290.1_SA1 | cds-NP_009503.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:133518-134512:+ | gene-YBL050W_ThermosaccDry | rna-NM_001178290.1_ThermosaccDry | cds-NP_009503.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:115686-116680:+ | gene-YBL050W_VR1 | rna-NM_001178290.1_VR1 | cds-NP_009503.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:110227-111221:+ | gene-YBL050W_ZTW1 | rna-NM_001178290.1_ZTW1 | cds-NP_009503.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:144901-145897:+ | gene-YBL050W_Sparadoxus | rna-NM_001178290.1_Sparadoxus | cds-NP_009503.1_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |