Gene name: SEC15
Reference locus (S288C): YGL233W
Gene biotype: protein_coding
Description: Essential 113 kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; interacts with and functions as a downstream effector of active, GTP-bound Sec4p, a Rab family GTPase
Top 10 interactors (score): SEC10 (0.999); SEC3 (0.999); SEC8 (0.999); SEC2 (0.999); SEC6 (0.999); SEC5 (0.999); EXO70 (0.999); EXO84 (0.999); SEC4 (0.999); MYO2 (0.997); CDC42 (0.995); SEC9 (0.989); BEM1 (0.984); SEC1 (0.982); RHO3 (0.976); SRO7 (0.964); RCY1 (0.959); YPT31 (0.958); YPT32 (0.951); SNC2 (0.924)
Homologues (species, bitscore): EXOC6B (Homo sapiens, 102.1); Exoc6b (Mus musculus, 103.6); exoc6b (Danio rerio, 98.6); exoc6 (Xenopus tropicalis, 98.2); Sec15 (Drosophila melanogaster, 59.7); sec-15 (Caenorhabditis elegans, 89.0); SEC15A (Arabidopsis thaliana, 82.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:60656-63388:+ | gene-YGL233W_AKU4011 | rna-NM_001181099.1_AKU4011 | cds-NP_011281.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:52690-55422:+ | gene-YGL233W_BG1 | rna-NM_001181099.1_BG1 | cds-NP_011281.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:61011-63743:+ | gene-YGL233W_Bruggeman | rna-NM_001181099.1_Bruggeman | cds-NP_011281.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:59077-61809:+ | gene-YGL233W_CAT1 | rna-NM_001181099.1_CAT1 | cds-NP_011281.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:64943-67675:+ | gene-YGL233W_CBS1585 | rna-NM_001181099.1_CBS1585 | cds-NP_011281.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:59663-62395:+ | gene-YGL233W_CBS436 | rna-NM_001181099.1_CBS436 | cds-NP_011281.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:52513-55245:+ | gene-YGL233W_CBS6412 | rna-NM_001181099.1_CBS6412 | cds-NP_011281.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:58803-61535:+ | gene-YGL233W_CBS6413 | rna-NM_001181099.1_CBS6413 | cds-NP_011281.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:58801-61533:+ | gene-YGL233W_CENPK1137D | rna-NM_001181099.1_CENPK1137D | cds-NP_011281.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:51743-54475:+ | gene-YGL233W_EthanolRed | rna-NM_001181099.1_EthanolRed | cds-NP_011281.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:52328-55060:+ | gene-YGL233W_FaliES1 | rna-NM_001181099.1_FaliES1 | cds-NP_011281.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:12064-14796:- | gene-YGL233W_JAY291 | rna-NM_001181099.1_JAY291 | cds-NP_011281.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:60938-63670:+ | gene-YGL233W_MUCL30387 | rna-NM_001181099.1_MUCL30387 | cds-NP_011281.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:63102-65834:+ | gene-YGL233W_MUCL30388 | rna-NM_001181099.1_MUCL30388 | cds-NP_011281.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:61540-64272:+ | gene-YGL233W_MUCL39482 | rna-NM_001181099.1_MUCL39482 | cds-NP_011281.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:64422-67154:+ | gene-YGL233W_MUCL42920 | rna-NM_001181099.1_MUCL42920 | cds-NP_011281.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:59122-61854:+ | gene-YGL233W_NCIM3186 | rna-NM_001181099.1_NCIM3186 | cds-NP_011281.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:53301-56033:+ | gene-YGL233W_NCYC1407 | rna-NM_001181099.1_NCYC1407 | cds-NP_011281.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:55158-57890:+ | gene-YGL233W_PE2H3 | rna-NM_001181099.1_PE2H3 | cds-NP_011281.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:54706-57438:+ | gene-YGL233W_PE2H4 | rna-NM_001181099.1_PE2H4 | cds-NP_011281.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:59122-61854:+ | gene-YGL233W_S288C | rna-NM_001181099.1_S288C | cds-NP_011281.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:313476-316208:- | gene-YGL233W_SA1 | rna-NM_001181099.1_SA1 | cds-NP_011281.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:52634-55366:+ | gene-YGL233W_ThermosaccDry | rna-NM_001181099.1_ThermosaccDry | cds-NP_011281.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:59592-62324:+ | gene-YGL233W_VR1 | rna-NM_001181099.1_VR1 | cds-NP_011281.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:51679-54411:+ | gene-YGL233W_ZTW1 | rna-NM_001181099.1_ZTW1 | cds-NP_011281.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:60317-63049:+ | gene-YGL233W_Sparadoxus | rna-NM_001181099.1_Sparadoxus | cds-NP_011281.1_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |