Gene name: SEC11
Reference locus (S288C): YIR022W
Gene biotype: protein_coding
Description: 18kDa catalytic subunit of the Signal Peptidase Complex (SPC); the Signal Peptidase Complex cleaves the signal sequence of proteins targeted to the endoplasmic reticulum; other members are Spc1p, Spc2p, Spc3p, and Sec11p
Top 10 interactors (score): SPC2 (0.999); SPC3 (0.999); SPC1 (0.999); SBH2 (0.944); SEC1 (0.942); ERV25 (0.935); OST3 (0.933); SBH1 (0.908); YPF1 (0.907); RBD2 (0.907); SEC4 (0.906); OST6 (0.896); SEC9 (0.89); SEC6 (0.867); BOS1 (0.814); SEC2 (0.814); SEC63 (0.8); SEC15 (0.789); SPC25 (0.788); SEC65 (0.767)
Homologues (species, bitscore): SEC11C (Homo sapiens, 145.6); Sec11a (Mus musculus, 149.1); sec11a (Danio rerio, 148.7); sec11a (Xenopus tropicalis, 149.1); twr (Drosophila melanogaster, 154.5); Y54E10BR.5 (Caenorhabditis elegans, 152.5); AT3G15710 (Arabidopsis thaliana, 137.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:396929-397432:+ | gene-YIR022W_AKU4011 | rna-NM_001179544.1_AKU4011 | cds-NP_012288.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:29430-29933:- | gene-YIR022W_BG1 | rna-NM_001179544.1_BG1 | cds-NP_012288.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:402807-403310:+ | gene-YIR022W_Bruggeman | rna-NM_001179544.1_Bruggeman | cds-NP_012288.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:388097-388600:+ | gene-YIR022W_CAT1 | rna-NM_001179544.1_CAT1 | cds-NP_012288.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:397910-398413:+ | gene-YIR022W_CBS1585 | rna-NM_001179544.1_CBS1585 | cds-NP_012288.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:389912-390415:+ | gene-YIR022W_CBS436 | rna-NM_001179544.1_CBS436 | cds-NP_012288.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:96415-96918:+ | gene-YIR022W_CBS6412 | rna-NM_001179544.1_CBS6412 | cds-NP_012288.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:389011-389514:+ | gene-YIR022W_CBS6413 | rna-NM_001179544.1_CBS6413 | cds-NP_012288.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:390394-390897:+ | gene-YIR022W_CENPK1137D | rna-NM_001179544.1_CENPK1137D | cds-NP_012288.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:379874-380377:+ | gene-YIR022W_EthanolRed | rna-NM_001179544.1_EthanolRed | cds-NP_012288.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:399702-400205:+ | gene-YIR022W_FaliES1 | rna-NM_001179544.1_FaliES1 | cds-NP_012288.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000039.1:33942-34445:- | gene-YIR022W_JAY291 | rna-NM_001179544.1_JAY291 | cds-NP_012288.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:403929-404432:+ | gene-YIR022W_MUCL30387 | rna-NM_001179544.1_MUCL30387 | cds-NP_012288.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:398550-399053:+ | gene-YIR022W_MUCL30388 | rna-NM_001179544.1_MUCL30388 | cds-NP_012288.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:398056-398559:+ | gene-YIR022W_MUCL39482 | rna-NM_001179544.1_MUCL39482 | cds-NP_012288.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:404394-404897:+ | gene-YIR022W_MUCL42920 | rna-NM_001179544.1_MUCL42920 | cds-NP_012288.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:398733-399236:+ | gene-YIR022W_NCIM3186 | rna-NM_001179544.1_NCIM3186 | cds-NP_012288.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:401820-402323:+ | gene-YIR022W_NCYC1407 | rna-NM_001179544.1_NCYC1407 | cds-NP_012288.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:392687-393190:+ | gene-YIR022W_PE2H3 | rna-NM_001179544.1_PE2H3 | cds-NP_012288.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:387393-387896:+ | gene-YIR022W_PE2H4 | rna-NM_001179544.1_PE2H4 | cds-NP_012288.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:398733-399236:+ | gene-YIR022W_S288C | rna-NM_001179544.1_S288C | cds-NP_012288.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000097.1:29606-30109:- | gene-YIR022W_SA1 | rna-NM_001179544.1_SA1 | cds-NP_012288.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:396567-397070:+ | gene-YIR022W_ThermosaccDry | rna-NM_001179544.1_ThermosaccDry | cds-NP_012288.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:393920-394423:+ | gene-YIR022W_VR1 | rna-NM_001179544.1_VR1 | cds-NP_012288.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000020.1:5745-6248:+ | gene-YIR022W_ZTW1 | rna-NM_001179544.1_ZTW1 | cds-NP_012288.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:394246-394749:+ | gene-YIR022W_Sparadoxus | rna-NM_001179544.1_Sparadoxus | cds-NP_012288.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |