SEC1 (YDR164C)


Gene profile

Gene name: SEC1
Reference locus (S288C): YDR164C
Gene biotype: protein_coding

Description: Sm-like protein involved in docking and fusion of exocytic vesicles; binds to assembled SNARE complexes at the membrane and stimulates membrane fusion; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function; interacts directly with essential exocyst subunit Sec6p

Top 10 interactors (score): SEC9 (0.999); SSO2 (0.999); SSO1 (0.999); SEC4 (0.997); SEC6 (0.996); SNC2 (0.995); SPO20 (0.995); VPS45 (0.993); VPS33 (0.991); SEC18 (0.99); SEC17 (0.988); YPT1 (0.985); EXO70 (0.984); MSO1 (0.984); YPT7 (0.983); SEC15 (0.982); SEC10 (0.976); SNC1 (0.968); SEC8 (0.967); VPS16 (0.967)

Homologues (species, bitscore): STXBP2 (Homo sapiens, 203.4); Stxbp2 (Mus musculus, 216.5); stxbp2 (Danio rerio, 195.3); stxbp1 (Xenopus tropicalis, 192.6); Rop (Drosophila melanogaster, 176.8); unc-18 (Caenorhabditis elegans, 189.9); SEC1B (Arabidopsis thaliana, 136.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:753337-755511:- gene-YDR164C_AKU4011 rna-NM_001180471.1_AKU4011 cds-NP_010448.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:371244-373418:+ gene-YDR164C_BG1 rna-NM_001180471.1_BG1 cds-NP_010448.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:784834-787008:- gene-YDR164C_Bruggeman rna-NM_001180471.1_Bruggeman cds-NP_010448.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:772109-774283:- gene-YDR164C_CAT1 rna-NM_001180471.1_CAT1 cds-NP_010448.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:743704-745878:- gene-YDR164C_CBS1585 rna-NM_001180471.1_CBS1585 cds-NP_010448.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:769897-772071:- gene-YDR164C_CBS436 rna-NM_001180471.1_CBS436 cds-NP_010448.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:739154-741328:- gene-YDR164C_CBS6412 rna-NM_001180471.1_CBS6412 cds-NP_010448.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:767602-769776:- gene-YDR164C_CBS6413 rna-NM_001180471.1_CBS6413 cds-NP_010448.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:782703-784877:- gene-YDR164C_CENPK1137D rna-NM_001180471.1_CENPK1137D cds-NP_010448.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:753163-755337:- gene-YDR164C_EthanolRed rna-NM_001180471.1_EthanolRed cds-NP_010448.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:761375-763549:- gene-YDR164C_FaliES1 rna-NM_001180471.1_FaliES1 cds-NP_010448.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000119.1:18713-20887:+ gene-YDR164C_JAY291 rna-NM_001180471.1_JAY291 cds-NP_010448.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:770212-772386:- gene-YDR164C_MUCL30387 rna-NM_001180471.1_MUCL30387 cds-NP_010448.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:758722-760896:- gene-YDR164C_MUCL30388 rna-NM_001180471.1_MUCL30388 cds-NP_010448.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:745131-747305:- gene-YDR164C_MUCL39482 rna-NM_001180471.1_MUCL39482 cds-NP_010448.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:682956-685130:- gene-YDR164C_MUCL42920 rna-NM_001180471.1_MUCL42920 cds-NP_010448.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:781964-784138:- gene-YDR164C_NCIM3186 rna-NM_001180471.1_NCIM3186 cds-NP_010448.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:744535-746709:- gene-YDR164C_NCYC1407 rna-NM_001180471.1_NCYC1407 cds-NP_010448.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:763729-765903:- gene-YDR164C_PE2H3 rna-NM_001180471.1_PE2H3 cds-NP_010448.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:763034-765208:- gene-YDR164C_PE2H4 rna-NM_001180471.1_PE2H4 cds-NP_010448.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:782041-784215:- gene-YDR164C_S288C rna-NM_001180471.1_S288C cds-NP_010448.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:129240-131414:- gene-YDR164C_SA1 rna-NM_001180471.1_SA1 cds-NP_010448.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:759510-761684:- gene-YDR164C_ThermosaccDry rna-NM_001180471.1_ThermosaccDry cds-NP_010448.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:774498-776672:- gene-YDR164C_VR1 rna-NM_001180471.1_VR1 cds-NP_010448.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:22261-24435:- gene-YDR164C_ZTW1 rna-NM_001180471.1_ZTW1 cds-NP_010448.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:765735-767909:- gene-YDR164C_Sparadoxus rna-NM_001180471.1_Sparadoxus cds-NP_010448.1_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files