Gene name: SDT1
Reference locus (S288C): YGL224C
Gene biotype: protein_coding
Description: Suppressor of disruption of TFIIS; Pyrimidine nucleotidase; responsible for production of nicotinamide riboside and nicotinic acid riboside; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives; SDT1 has a paralog, PHM8, that arose from the whole genome duplication
Top 10 interactors (score): URH1 (0.99); ISN1 (0.989); PNP1 (0.983); NMA2 (0.976); NMA1 (0.975); NPY1 (0.96); BNA6 (0.936); NPT1 (0.916); POF1 (0.9); GUD1 (0.863); MET22 (0.811); QNS1 (0.736); PNC1 (0.723); PRM15 (0.695); FUN26 (0.691); MEU1 (0.666); XPT1 (0.658); URK1 (0.645); PHO8 (0.633); MCH1 (0.575)
Homologues (species, bitscore): AT3G62040 (Arabidopsis thaliana, 99.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:79289-80131:- | gene-YGL224C_AKU4011 | rna-NM_001181089.1_AKU4011 | cds-NP_011291.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:72452-73294:- | gene-YGL224C_BG1 | rna-NM_001181089.1_BG1 | cds-NP_011291.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:79888-80730:- | gene-YGL224C_Bruggeman | rna-NM_001181089.1_Bruggeman | cds-NP_011291.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:78573-79415:- | gene-YGL224C_CAT1 | rna-NM_001181089.1_CAT1 | cds-NP_011291.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:83571-84413:- | gene-YGL224C_CBS1585 | rna-NM_001181089.1_CBS1585 | cds-NP_011291.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:79250-80092:- | gene-YGL224C_CBS436 | rna-NM_001181089.1_CBS436 | cds-NP_011291.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:71141-71975:- | gene-YGL224C_CBS6412 | rna-NM_001181089.1_CBS6412 | cds-NP_011291.1_CBS6412 | 82.9 | 92.6 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:77433-78275:- | gene-YGL224C_CBS6413 | rna-NM_001181089.1_CBS6413 | cds-NP_011291.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:78046-78888:- | gene-YGL224C_CENPK1137D | rna-NM_001181089.1_CENPK1137D | cds-NP_011291.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:70374-71192:- | gene-YGL224C_EthanolRed | rna-NM_001181089.1_EthanolRed | cds-NP_011291.1_EthanolRed | 95.8 | 97.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:70959-71801:- | gene-YGL224C_FaliES1 | rna-NM_001181089.1_FaliES1 | cds-NP_011291.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000328.1:1674-2516:+ | gene-YGL224C_JAY291 | rna-NM_001181089.1_JAY291 | cds-NP_011291.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:79816-80658:- | gene-YGL224C_MUCL30387 | rna-NM_001181089.1_MUCL30387 | cds-NP_011291.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:81979-82821:- | gene-YGL224C_MUCL30388 | rna-NM_001181089.1_MUCL30388 | cds-NP_011291.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:80168-81010:- | gene-YGL224C_MUCL39482 | rna-NM_001181089.1_MUCL39482 | cds-NP_011291.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:83299-84141:- | gene-YGL224C_MUCL42920 | rna-NM_001181089.1_MUCL42920 | cds-NP_011291.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:78015-78857:- | gene-YGL224C_NCIM3186 | rna-NM_001181089.1_NCIM3186 | cds-NP_011291.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:71928-72770:- | gene-YGL224C_NCYC1407 | rna-NM_001181089.1_NCYC1407 | cds-NP_011291.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:74739-75581:- | gene-YGL224C_PE2H3 | rna-NM_001181089.1_PE2H3 | cds-NP_011291.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:74287-75129:- | gene-YGL224C_PE2H4 | rna-NM_001181089.1_PE2H4 | cds-NP_011291.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:78015-78857:- | gene-YGL224C_S288C | rna-NM_001181089.1_S288C | cds-NP_011291.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:296460-297302:+ | gene-YGL224C_SA1 | rna-NM_001181089.1_SA1 | cds-NP_011291.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:71265-72107:- | gene-YGL224C_ThermosaccDry | rna-NM_001181089.1_ThermosaccDry | cds-NP_011291.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:79181-80023:- | gene-YGL224C_VR1 | rna-NM_001181089.1_VR1 | cds-NP_011291.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:70307-71149:- | gene-YGL224C_ZTW1 | rna-NM_001181089.1_ZTW1 | cds-NP_011291.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:77396-78238:- | gene-YGL224C_Sparadoxus | rna-NM_001181089.1_Sparadoxus | cds-NP_011291.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |