Gene name: SDO1
Reference locus (S288C): YLR022C
Gene biotype: protein_coding
Description: Ribosome maturation protein SDO1; Guanine nucleotide exchange factor (GEF) for Ria1p; essential protein involved in ribosome maturation; with Ria1p, promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archaea and eukaryotes; Belongs to the SDO1/SBDS family
Top 10 interactors (score): RIA1 (0.999); TIF6 (0.997); NIP7 (0.975); NMD3 (0.974); RTC3 (0.961); RLP24 (0.942); REI1 (0.933); LSG1 (0.922); RPL3 (0.907); MRT4 (0.905); JJJ1 (0.891); EFT2 (0.886); NOG1 (0.879); RPL10 (0.856); RPL5 (0.855); EFT1 (0.847); NOP53 (0.809); ARX1 (0.809); RPL24A (0.798); EMG1 (0.796)
Homologues (species, bitscore): SBDS (Homo sapiens, 186.8); Sbds (Mus musculus, 181.4); sbds (Danio rerio, 191.4); sbds (Xenopus tropicalis, 190.3); CG8549 (Drosophila melanogaster, 185.7); sbds-1 (Caenorhabditis elegans, 166.0); AT1G43860 (Arabidopsis thaliana, 151.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:172113-172865:- | gene-YLR022C_AKU4011 | rna-NM_001181909.1_AKU4011 | cds-NP_013122.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:135384-136136:- | gene-YLR022C_BG1 | rna-NM_001181909.1_BG1 | cds-NP_013122.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:182508-183260:- | gene-YLR022C_Bruggeman | rna-NM_001181909.1_Bruggeman | cds-NP_013122.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:182830-183582:- | gene-YLR022C_CAT1 | rna-NM_001181909.1_CAT1 | cds-NP_013122.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:179737-180489:- | gene-YLR022C_CBS1585 | rna-NM_001181909.1_CBS1585 | cds-NP_013122.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:170371-171123:- | gene-YLR022C_CBS436 | rna-NM_001181909.1_CBS436 | cds-NP_013122.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:178148-178900:- | gene-YLR022C_CBS6412 | rna-NM_001181909.1_CBS6412 | cds-NP_013122.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:180000-180752:- | gene-YLR022C_CBS6413 | rna-NM_001181909.1_CBS6413 | cds-NP_013122.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:169424-170176:- | gene-YLR022C_CENPK1137D | rna-NM_001181909.1_CENPK1137D | cds-NP_013122.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:172125-172877:- | gene-YLR022C_EthanolRed | rna-NM_001181909.1_EthanolRed | cds-NP_013122.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:171695-172447:- | gene-YLR022C_FaliES1 | rna-NM_001181909.1_FaliES1 | cds-NP_013122.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000431.1:15889-16641:- | gene-YLR022C_JAY291 | rna-NM_001181909.1_JAY291 | cds-NP_013122.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:179855-180607:- | gene-YLR022C_MUCL30387 | rna-NM_001181909.1_MUCL30387 | cds-NP_013122.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:186478-187230:- | gene-YLR022C_MUCL30388 | rna-NM_001181909.1_MUCL30388 | cds-NP_013122.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:180232-180984:- | gene-YLR022C_MUCL39482 | rna-NM_001181909.1_MUCL39482 | cds-NP_013122.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:180134-180886:- | gene-YLR022C_MUCL42920 | rna-NM_001181909.1_MUCL42920 | cds-NP_013122.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:184148-184900:- | gene-YLR022C_NCIM3186 | rna-NM_001181909.1_NCIM3186 | cds-NP_013122.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:171852-172604:- | gene-YLR022C_NCYC1407 | rna-NM_001181909.1_NCYC1407 | cds-NP_013122.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:178167-178919:- | gene-YLR022C_PE2H3 | rna-NM_001181909.1_PE2H3 | cds-NP_013122.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:177908-178660:- | gene-YLR022C_PE2H4 | rna-NM_001181909.1_PE2H4 | cds-NP_013122.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:184174-184926:- | gene-YLR022C_S288C | rna-NM_001181909.1_S288C | cds-NP_013122.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:16024-16776:- | gene-YLR022C_SA1 | rna-NM_001181909.1_SA1 | cds-NP_013122.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:172199-172951:- | gene-YLR022C_ThermosaccDry | rna-NM_001181909.1_ThermosaccDry | cds-NP_013122.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:185618-186370:- | gene-YLR022C_VR1 | rna-NM_001181909.1_VR1 | cds-NP_013122.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:171564-172316:- | gene-YLR022C_ZTW1 | rna-NM_001181909.1_ZTW1 | cds-NP_013122.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:180362-181114:- | gene-YLR022C_Sparadoxus | rna-NM_001181909.1_Sparadoxus | cds-NP_013122.1_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |