Gene name: SDH5
Reference locus (S288C): YOL071W
Gene biotype: protein_coding
Description: Succinate dehydrogenase assembly factor 2, mitochondrial; Protein required for flavinylation of Sdh1p; binds to Sdh1p and promotes FAD cofactor attachment, which is necessary for succinate dehydrogenase (SDH) complex assembly and activity; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma)
Top 10 interactors (score): SDH1 (0.998); YJL045W (0.986); SDH6 (0.944); TCM62 (0.893); SDH4 (0.89); HUB1 (0.886); MRPL16 (0.873); SDH3 (0.842); SDH2 (0.841); LAT1 (0.838); SDH7 (0.829); FLX1 (0.82); RRG9 (0.697); SRF1 (0.696); PUF3 (0.669); ERV25 (0.662); FRD1 (0.654); OSM1 (0.654); AIM45 (0.649); MDN1 (0.647)
Homologues (species, bitscore): SDHAF2 (Homo sapiens, 94.0); Sdhaf2 (Mus musculus, 97.1); sdhaf2 (Danio rerio, 92.0); sdhaf2 (Xenopus tropicalis, 87.0); CG12895 (Drosophila melanogaster, 95.9); Y57A10A.29 (Caenorhabditis elegans, 79.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:180166-180654:+ | gene-YOL071W_AKU4011 | rna-NM_001183326.1_AKU4011 | cds-NP_014570.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:144955-145443:+ | gene-YOL071W_BG1 | rna-NM_001183326.1_BG1 | cds-NP_014570.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:181833-182321:+ | gene-YOL071W_Bruggeman | rna-NM_001183326.1_Bruggeman | cds-NP_014570.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:181347-181835:+ | gene-YOL071W_CAT1 | rna-NM_001183326.1_CAT1 | cds-NP_014570.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:174557-175045:+ | gene-YOL071W_CBS1585 | rna-NM_001183326.1_CBS1585 | cds-NP_014570.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:179722-180210:+ | gene-YOL071W_CBS436 | rna-NM_001183326.1_CBS436 | cds-NP_014570.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:174487-174975:+ | gene-YOL071W_CBS6412 | rna-NM_001183326.1_CBS6412 | cds-NP_014570.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:181422-181910:+ | gene-YOL071W_CBS6413 | rna-NM_001183326.1_CBS6413 | cds-NP_014570.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:196259-196747:+ | gene-YOL071W_CENPK1137D | rna-NM_001183326.1_CENPK1137D | cds-NP_014570.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:177316-177754:+ | gene-YOL071W_EthanolRed | rna-NM_001183326.1_EthanolRed | cds-NP_014570.1_EthanolRed | 87.3 | 89.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:179809-180297:+ | gene-YOL071W_FaliES1 | rna-NM_001183326.1_FaliES1 | cds-NP_014570.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:85262-85750:- | gene-YOL071W_JAY291 | rna-NM_001183326.1_JAY291 | cds-NP_014570.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:185603-186091:+ | gene-YOL071W_MUCL30387 | rna-NM_001183326.1_MUCL30387 | cds-NP_014570.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:189282-189770:+ | gene-YOL071W_MUCL30388 | rna-NM_001183326.1_MUCL30388 | cds-NP_014570.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:182478-182966:+ | gene-YOL071W_MUCL39482 | rna-NM_001183326.1_MUCL39482 | cds-NP_014570.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:197955-198443:+ | gene-YOL071W_MUCL42920 | rna-NM_001183326.1_MUCL42920 | cds-NP_014570.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:196396-196884:+ | gene-YOL071W_NCIM3186 | rna-NM_001183326.1_NCIM3186 | cds-NP_014570.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:189094-189582:+ | gene-YOL071W_NCYC1407 | rna-NM_001183326.1_NCYC1407 | cds-NP_014570.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:172075-172563:+ | gene-YOL071W_PE2H3 | rna-NM_001183326.1_PE2H3 | cds-NP_014570.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:183065-183553:+ | gene-YOL071W_PE2H4 | rna-NM_001183326.1_PE2H4 | cds-NP_014570.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:196507-196995:+ | gene-YOL071W_S288C | rna-NM_001183326.1_S288C | cds-NP_014570.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:164399-164887:+ | gene-YOL071W_SA1 | rna-NM_001183326.1_SA1 | cds-NP_014570.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:178817-179305:+ | gene-YOL071W_ThermosaccDry | rna-NM_001183326.1_ThermosaccDry | cds-NP_014570.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:179575-180063:+ | gene-YOL071W_VR1 | rna-NM_001183326.1_VR1 | cds-NP_014570.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:178461-178949:+ | gene-YOL071W_ZTW1 | rna-NM_001183326.1_ZTW1 | cds-NP_014570.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:182019-182507:+ | gene-YOL071W_Sparadoxus | rna-NM_001183326.1_Sparadoxus | cds-NP_014570.1_Sparadoxus | 88.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |