Gene name: SDH3
Reference locus (S288C): YKL141W
Gene biotype: protein_coding
Description: Subunit of succinate dehydrogenase and of TIM22 translocase; functions as cytochrome b subunit of succinate dehydrogenase, which couples oxidation of succinate to transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; also required for mitochondrial inner membrane protein import as part of the TIM22 complex; SDH3 has a paralog, SHH3, that arose from the whole genome duplication
Top 10 interactors (score): SDH1 (0.999); SDH4 (0.999); SDH2 (0.999); TIM18 (0.999); TIM54 (0.997); FUM1 (0.996); YJL045W (0.995); TIM22 (0.994); RIP1 (0.993); SHH4 (0.993); TIM12 (0.993); QCR8 (0.992); TIM9 (0.989); QCR2 (0.987); LSC1 (0.985); COB (0.978); CYT1 (0.976); LSC2 (0.957); SHH3 (0.956); QCR9 (0.956)
Homologues (species, bitscore): Sdhc (Mus musculus, 50.8); sdhc (Danio rerio, 50.4); sdhc (Xenopus tropicalis, 57.8); SdhC (Drosophila melanogaster, 77.4); mev-1 (Caenorhabditis elegans, 67.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:166550-167146:+ | gene-YKL141W_AKU4011 | rna-NM_001179707.1_AKU4011 | cds-NP_012781.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:143706-144302:+ | gene-YKL141W_BG1 | rna-NM_001179707.1_BG1 | cds-NP_012781.1_BG1 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:184213-184809:+ | gene-YKL141W_Bruggeman | rna-NM_001179707.1_Bruggeman | cds-NP_012781.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:179525-180121:+ | gene-YKL141W_CAT1 | rna-NM_001179707.1_CAT1 | cds-NP_012781.1_CAT1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:178801-179397:+ | gene-YKL141W_CBS1585 | rna-NM_001179707.1_CBS1585 | cds-NP_012781.1_CBS1585 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:177379-177975:+ | gene-YKL141W_CBS436 | rna-NM_001179707.1_CBS436 | cds-NP_012781.1_CBS436 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:163424-164020:+ | gene-YKL141W_CBS6412 | rna-NM_001179707.1_CBS6412 | cds-NP_012781.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:179247-179843:+ | gene-YKL141W_CBS6413 | rna-NM_001179707.1_CBS6413 | cds-NP_012781.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:179311-179907:+ | gene-YKL141W_CENPK1137D | rna-NM_001179707.1_CENPK1137D | cds-NP_012781.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:177282-177878:+ | gene-YKL141W_EthanolRed | rna-NM_001179707.1_EthanolRed | cds-NP_012781.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:178094-178690:+ | gene-YKL141W_FaliES1 | rna-NM_001179707.1_FaliES1 | cds-NP_012781.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:417-1013:+ | gene-YKL141W_JAY291 | rna-NM_001179707.1_JAY291 | cds-NP_012781.1_JAY291 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:186310-186906:+ | gene-YKL141W_MUCL30387 | rna-NM_001179707.1_MUCL30387 | cds-NP_012781.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:180662-181258:+ | gene-YKL141W_MUCL30388 | rna-NM_001179707.1_MUCL30388 | cds-NP_012781.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:178580-179176:+ | gene-YKL141W_MUCL39482 | rna-NM_001179707.1_MUCL39482 | cds-NP_012781.1_MUCL39482 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:182971-183567:+ | gene-YKL141W_MUCL42920 | rna-NM_001179707.1_MUCL42920 | cds-NP_012781.1_MUCL42920 | 97.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:179656-180252:+ | gene-YKL141W_NCIM3186 | rna-NM_001179707.1_NCIM3186 | cds-NP_012781.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:178770-179366:+ | gene-YKL141W_NCYC1407 | rna-NM_001179707.1_NCYC1407 | cds-NP_012781.1_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:185885-186481:+ | gene-YKL141W_PE2H3 | rna-NM_001179707.1_PE2H3 | cds-NP_012781.1_PE2H3 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:182169-182765:+ | gene-YKL141W_PE2H4 | rna-NM_001179707.1_PE2H4 | cds-NP_012781.1_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:179667-180263:+ | gene-YKL141W_S288C | rna-NM_001179707.1_S288C | cds-NP_012781.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:96110-96706:+ | gene-YKL141W_SA1 | rna-NM_001179707.1_SA1 | cds-NP_012781.1_SA1 | 97.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:178794-179390:+ | gene-YKL141W_ThermosaccDry | rna-NM_001179707.1_ThermosaccDry | cds-NP_012781.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:178145-178741:+ | gene-YKL141W_VR1 | rna-NM_001179707.1_VR1 | cds-NP_012781.1_VR1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:177330-177926:+ | gene-YKL141W_ZTW1 | rna-NM_001179707.1_ZTW1 | cds-NP_012781.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:194044-194640:+ | gene-YKL141W_Sparadoxus | rna-NM_001179707.1_Sparadoxus | cds-NP_012781.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |