Gene name: SDH1
Reference locus (S288C): YKL148C
Gene biotype: protein_coding
Description: Flavoprotein subunit of succinate dehydrogenase; couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; FAD binding to Sdh1p is required for the assembly of the succinate dehydrogenase subunits; mutations in human ortholog SDHA are associated with Leigh syndrome
Top 10 interactors (score): SDH2 (0.999); SDH4 (0.999); SDH3 (0.999); RIP1 (0.999); SDH5 (0.998); CYT1 (0.997); QCR2 (0.996); COR1 (0.995); NDI1 (0.993); SHH3 (0.988); LSC1 (0.986); FUM1 (0.985); COB (0.981); LSC2 (0.978); QCR7 (0.968); YJL045W (0.96); KGD2 (0.959); QCR9 (0.952); QCR6 (0.952); MDH1 (0.945)
Homologues (species, bitscore): SDHA (Homo sapiens, 875.9); Sdha (Mus musculus, 878.2); sdha (Danio rerio, 887.1); sdha (Xenopus tropicalis, 803.9); SdhA (Drosophila melanogaster, 877.1); sdha-1 (Caenorhabditis elegans, 832.4); SDH1-1 (Arabidopsis thaliana, 887.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:156081-158003:- | gene-YKL148C_AKU4011 | rna-NM_001179714.1_AKU4011 | cds-NP_012774.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:133214-135136:- | gene-YKL148C_BG1 | rna-NM_001179714.1_BG1 | cds-NP_012774.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:173743-175665:- | gene-YKL148C_Bruggeman | rna-NM_001179714.1_Bruggeman | cds-NP_012774.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:169068-170990:- | gene-YKL148C_CAT1 | rna-NM_001179714.1_CAT1 | cds-NP_012774.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:168311-170233:- | gene-YKL148C_CBS1585 | rna-NM_001179714.1_CBS1585 | cds-NP_012774.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:166915-168837:- | gene-YKL148C_CBS436 | rna-NM_001179714.1_CBS436 | cds-NP_012774.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:153326-155248:- | gene-YKL148C_CBS6412 | rna-NM_001179714.1_CBS6412 | cds-NP_012774.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:168776-170698:- | gene-YKL148C_CBS6413 | rna-NM_001179714.1_CBS6413 | cds-NP_012774.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:168851-170773:- | gene-YKL148C_CENPK1137D | rna-NM_001179714.1_CENPK1137D | cds-NP_012774.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:166815-168737:- | gene-YKL148C_EthanolRed | rna-NM_001179714.1_EthanolRed | cds-NP_012774.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:167627-169549:- | gene-YKL148C_FaliES1 | rna-NM_001179714.1_FaliES1 | cds-NP_012774.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000198.1:4341-6263:- | gene-YKL148C_JAY291 | rna-NM_001179714.1_JAY291 | cds-NP_012774.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:175840-177762:- | gene-YKL148C_MUCL30387 | rna-NM_001179714.1_MUCL30387 | cds-NP_012774.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:170192-172114:- | gene-YKL148C_MUCL30388 | rna-NM_001179714.1_MUCL30388 | cds-NP_012774.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:168112-170034:- | gene-YKL148C_MUCL39482 | rna-NM_001179714.1_MUCL39482 | cds-NP_012774.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:172517-174439:- | gene-YKL148C_MUCL42920 | rna-NM_001179714.1_MUCL42920 | cds-NP_012774.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:169196-171118:- | gene-YKL148C_NCIM3186 | rna-NM_001179714.1_NCIM3186 | cds-NP_012774.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:168303-170225:- | gene-YKL148C_NCYC1407 | rna-NM_001179714.1_NCYC1407 | cds-NP_012774.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:175403-177325:- | gene-YKL148C_PE2H3 | rna-NM_001179714.1_PE2H3 | cds-NP_012774.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:171697-173619:- | gene-YKL148C_PE2H4 | rna-NM_001179714.1_PE2H4 | cds-NP_012774.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:169207-171129:- | gene-YKL148C_S288C | rna-NM_001179714.1_S288C | cds-NP_012774.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:85628-87550:- | gene-YKL148C_SA1 | rna-NM_001179714.1_SA1 | cds-NP_012774.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:168327-170249:- | gene-YKL148C_ThermosaccDry | rna-NM_001179714.1_ThermosaccDry | cds-NP_012774.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:167679-169601:- | gene-YKL148C_VR1 | rna-NM_001179714.1_VR1 | cds-NP_012774.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:166861-168783:- | gene-YKL148C_ZTW1 | rna-NM_001179714.1_ZTW1 | cds-NP_012774.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:183556-185478:- | gene-YKL148C_Sparadoxus | rna-NM_001179714.1_Sparadoxus | cds-NP_012774.1_Sparadoxus | 92.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |