Gene name: SDD2
Reference locus (S288C): YMR074C
Gene biotype: protein_coding
Description: Uncharacterized protein YMR074C; Protein with homology to human PDCD5; PDCD5 is involved in programmed cell death; N-terminal region forms a conserved triple-helix bundle structure; overproduction suppresses lethality due to expression of the dominant PET9 allele AAC2-A128P; overexpression promotes H2O2-induced apoptosis; YMR074C is not an essential gene; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): GIM5 (0.939); YKE2 (0.924); PAC10 (0.907); SDD3 (0.9); SDD1 (0.896); YPL225W (0.89); SMX2 (0.889); PRE8 (0.875); SDD4 (0.845); RPL42B (0.771); RPL42A (0.771); TMA7 (0.759); MCA1 (0.729); RQC1 (0.685); PET9 (0.685); TFB5 (0.649); TMA20 (0.643); SME1 (0.623); NUC1 (0.616); SIT4 (0.608)
Homologues (species, bitscore): PDCD5 (Homo sapiens, 55.8); Pdcd5 (Mus musculus, 56.6); pdcd5 (Danio rerio, 64.7); pdcd5 (Xenopus tropicalis, 51.6); AT1G29850 (Arabidopsis thaliana, 50.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:450741-451178:- | gene-YMR074C_AKU4011 | rna-NM_001182572.1_AKU4011 | cds-NP_013790.1_AKU4011 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:91605-92042:+ | gene-YMR074C_BG1 | rna-NM_001182572.1_BG1 | cds-NP_013790.1_BG1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:392892-393329:- | gene-YMR074C_Bruggeman | rna-NM_001182572.1_Bruggeman | cds-NP_013790.1_Bruggeman | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:393255-393692:- | gene-YMR074C_CAT1 | rna-NM_001182572.1_CAT1 | cds-NP_013790.1_CAT1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:383684-384121:- | gene-YMR074C_CBS1585 | rna-NM_001182572.1_CBS1585 | cds-NP_013790.1_CBS1585 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:389237-389674:- | gene-YMR074C_CBS436 | rna-NM_001182572.1_CBS436 | cds-NP_013790.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:496757-497194:- | gene-YMR074C_CBS6412 | rna-NM_001182572.1_CBS6412 | cds-NP_013790.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:382941-383378:- | gene-YMR074C_CBS6413 | rna-NM_001182572.1_CBS6413 | cds-NP_013790.1_CBS6413 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:407141-407578:- | gene-YMR074C_CENPK1137D | rna-NM_001182572.1_CENPK1137D | cds-NP_013790.1_CENPK1137D | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:383546-383983:- | gene-YMR074C_EthanolRed | rna-NM_001182572.1_EthanolRed | cds-NP_013790.1_EthanolRed | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:386712-387149:- | gene-YMR074C_FaliES1 | rna-NM_001182572.1_FaliES1 | cds-NP_013790.1_FaliES1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:49806-50243:+ | gene-YMR074C_JAY291 | rna-NM_001182572.1_JAY291 | cds-NP_013790.1_JAY291 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:388624-389061:- | gene-YMR074C_MUCL30387 | rna-NM_001182572.1_MUCL30387 | cds-NP_013790.1_MUCL30387 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:393312-393749:- | gene-YMR074C_MUCL30388 | rna-NM_001182572.1_MUCL30388 | cds-NP_013790.1_MUCL30388 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:383972-384409:- | gene-YMR074C_MUCL39482 | rna-NM_001182572.1_MUCL39482 | cds-NP_013790.1_MUCL39482 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:390625-391062:- | gene-YMR074C_MUCL42920 | rna-NM_001182572.1_MUCL42920 | cds-NP_013790.1_MUCL42920 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:412990-413427:- | gene-YMR074C_NCIM3186 | rna-NM_001182572.1_NCIM3186 | cds-NP_013790.1_NCIM3186 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:383884-384321:- | gene-YMR074C_NCYC1407 | rna-NM_001182572.1_NCYC1407 | cds-NP_013790.1_NCYC1407 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:389836-390273:- | gene-YMR074C_PE2H3 | rna-NM_001182572.1_PE2H3 | cds-NP_013790.1_PE2H3 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:395931-396368:- | gene-YMR074C_PE2H4 | rna-NM_001182572.1_PE2H4 | cds-NP_013790.1_PE2H4 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:413036-413473:- | gene-YMR074C_S288C | rna-NM_001182572.1_S288C | cds-NP_013790.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:136696-137133:+ | gene-YMR074C_SA1 | rna-NM_001182572.1_SA1 | cds-NP_013790.1_SA1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:384515-384952:- | gene-YMR074C_ThermosaccDry | rna-NM_001182572.1_ThermosaccDry | cds-NP_013790.1_ThermosaccDry | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:396420-396857:- | gene-YMR074C_VR1 | rna-NM_001182572.1_VR1 | cds-NP_013790.1_VR1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:396338-396775:- | gene-YMR074C_Sparadoxus | rna-NM_001182572.1_Sparadoxus | cds-NP_013790.1_Sparadoxus | 93.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |