SCP160 (YJL080C)


Gene profile

Gene name: SCP160
Reference locus (S288C): YJL080C
Gene biotype: protein_coding

Description: Protein SCP160; Essential RNA-binding G protein effector of mating response pathway; ligand-activated RNA-binding protein that delivers RNAs involved in polarization and perpetualizing mating signal to shmoo tip during pheromone signaling; Scp160p-mediated RNA trafficking essential for chemotropism and successful mating; mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins

Top 10 interactors (score): BFR1 (0.988); ASC1 (0.972); SNF4 (0.962); EAP1 (0.944); PAB1 (0.926); SEC61 (0.909); TEF1 (0.907); PUF3 (0.902); SFB3 (0.9); LHS1 (0.896); HEK2 (0.895); DHH1 (0.872); NAM8 (0.852); HPF1 (0.85); YOR338W (0.848); TIF4631 (0.848); SNF1 (0.844); ZUO1 (0.829); HRB1 (0.789); MYO4 (0.787)

Homologues (species, bitscore): HDLBP (Homo sapiens, 171.0); Hdlbp (Mus musculus, 172.6); hdlbpb (Danio rerio, 171.0); hdlbp (Xenopus tropicalis, 167.2); Dp1 (Drosophila melanogaster, 175.6); vgln-1 (Caenorhabditis elegans, 124.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:268254-271922:- gene-YJL080C_AKU4011 rna-NM_001181513.1_AKU4011 cds-NP_012455.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:342514-346182:+ gene-YJL080C_BG1 rna-NM_001181513.1_BG1 cds-NP_012455.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:279700-283368:- gene-YJL080C_Bruggeman rna-NM_001181513.1_Bruggeman cds-NP_012455.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:284595-288263:- gene-YJL080C_CAT1 rna-NM_001181513.1_CAT1 cds-NP_012455.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:279914-283582:- gene-YJL080C_CBS1585 rna-NM_001181513.1_CBS1585 cds-NP_012455.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:298047-301715:- gene-YJL080C_CBS436 rna-NM_001181513.1_CBS436 cds-NP_012455.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:269012-272680:- gene-YJL080C_CBS6412 rna-NM_001181513.1_CBS6412 cds-NP_012455.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:270367-274035:- gene-YJL080C_CBS6413 rna-NM_001181513.1_CBS6413 cds-NP_012455.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:268022-271690:- gene-YJL080C_CENPK1137D rna-NM_001181513.1_CENPK1137D cds-NP_012455.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:272104-275772:- gene-YJL080C_EthanolRed rna-NM_001181513.1_EthanolRed cds-NP_012455.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:283678-287346:- gene-YJL080C_FaliES1 rna-NM_001181513.1_FaliES1 cds-NP_012455.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000138.1:81317-84987:- gene-YJL080C_JAY291 rna-NM_001181513.1_JAY291 cds-NP_012455.1_JAY291 99.8 100.0 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:281970-285638:- gene-YJL080C_MUCL30387 rna-NM_001181513.1_MUCL30387 cds-NP_012455.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:278046-281714:- gene-YJL080C_MUCL30388 rna-NM_001181513.1_MUCL30388 cds-NP_012455.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:272672-276340:- gene-YJL080C_MUCL39482 rna-NM_001181513.1_MUCL39482 cds-NP_012455.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:278877-282545:- gene-YJL080C_MUCL42920 rna-NM_001181513.1_MUCL42920 cds-NP_012455.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:285537-289205:- gene-YJL080C_NCIM3186 rna-NM_001181513.1_NCIM3186 cds-NP_012455.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:271360-275028:- gene-YJL080C_NCYC1407 rna-NM_001181513.1_NCYC1407 cds-NP_012455.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:283744-287412:- gene-YJL080C_PE2H3 rna-NM_001181513.1_PE2H3 cds-NP_012455.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:283388-287056:- gene-YJL080C_PE2H4 rna-NM_001181513.1_PE2H4 cds-NP_012455.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:285558-289226:- gene-YJL080C_S288C rna-NM_001181513.1_S288C cds-NP_012455.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:81232-84900:- gene-YJL080C_SA1 rna-NM_001181513.1_SA1 cds-NP_012455.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:277093-280761:- gene-YJL080C_ThermosaccDry rna-NM_001181513.1_ThermosaccDry cds-NP_012455.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:278620-282288:- gene-YJL080C_VR1 rna-NM_001181513.1_VR1 cds-NP_012455.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:258446-262114:- gene-YJL080C_ZTW1 rna-NM_001181513.1_ZTW1 cds-NP_012455.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:282517-286182:- gene-YJL080C_Sparadoxus rna-NM_001181513.1_Sparadoxus cds-NP_012455.1_Sparadoxus 92.3 99.9 Verified 1 1 1 False True False False False

Additional files