Gene name: SCO1
Reference locus (S288C): YBR037C
Gene biotype: protein_coding
Description: Copper-binding protein of mitochondrial inner membrane; required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; similar to thioredoxins; SCO1 has a paralog, SCO2, that arose from the whole genome duplication
Top 10 interactors (score): COX17 (0.995); COX11 (0.989); COX2 (0.978); COX19 (0.956); COX15 (0.944); COX20 (0.938); COX10 (0.905); SHY1 (0.888); CCC2 (0.877); COX18 (0.87); RSM22 (0.86); SOD1 (0.824); COX1 (0.816); ATX1 (0.805); COX23 (0.773); PET191 (0.773); COX12 (0.764); MIA40 (0.752); OXA1 (0.728); YGR021W (0.724)
Homologues (species, bitscore): SCO1 (Homo sapiens, 164.5); Sco1 (Mus musculus, 164.5); sco2 (Danio rerio, 157.5); SCO2 (Xenopus tropicalis, 151.0); Scox (Drosophila melanogaster, 166.0); sco-1 (Caenorhabditis elegans, 142.5); HCC1 (Arabidopsis thaliana, 175.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:292999-293886:- | gene-YBR037C_AKU4011 | rna-NM_001178385.1_AKU4011 | cds-NP_009593.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:283139-284044:- | gene-YBR037C_BG1 | rna-NM_001178385.1_BG1 | cds-NP_009593.1_BG1 | 97.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:293726-294613:- | gene-YBR037C_Bruggeman | rna-NM_001178385.1_Bruggeman | cds-NP_009593.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:297416-298303:- | gene-YBR037C_CAT1 | rna-NM_001178385.1_CAT1 | cds-NP_009593.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:285296-286183:- | gene-YBR037C_CBS1585 | rna-NM_001178385.1_CBS1585 | cds-NP_009593.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:293300-294187:- | gene-YBR037C_CBS436 | rna-NM_001178385.1_CBS436 | cds-NP_009593.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:383180-384067:- | gene-YBR037C_CBS6412 | rna-NM_001178385.1_CBS6412 | cds-NP_009593.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:290412-291299:- | gene-YBR037C_CBS6413 | rna-NM_001178385.1_CBS6413 | cds-NP_009593.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:304331-305218:- | gene-YBR037C_CENPK1137D | rna-NM_001178385.1_CENPK1137D | cds-NP_009593.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:419777-420664:- | gene-YBR037C_EthanolRed | rna-NM_001178385.1_EthanolRed | cds-NP_009593.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:308627-309514:- | gene-YBR037C_FaliES1 | rna-NM_001178385.1_FaliES1 | cds-NP_009593.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000441.1:22210-23097:+ | gene-YBR037C_JAY291 | rna-NM_001178385.1_JAY291 | cds-NP_009593.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:295328-296233:- | gene-YBR037C_MUCL30387 | rna-NM_001178385.1_MUCL30387 | cds-NP_009593.1_MUCL30387 | 97.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:295132-296019:- | gene-YBR037C_MUCL30388 | rna-NM_001178385.1_MUCL30388 | cds-NP_009593.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:285284-286171:- | gene-YBR037C_MUCL39482 | rna-NM_001178385.1_MUCL39482 | cds-NP_009593.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:292478-293365:- | gene-YBR037C_MUCL42920 | rna-NM_001178385.1_MUCL42920 | cds-NP_009593.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:310362-311249:- | gene-YBR037C_NCIM3186 | rna-NM_001178385.1_NCIM3186 | cds-NP_009593.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:286196-287083:- | gene-YBR037C_NCYC1407 | rna-NM_001178385.1_NCYC1407 | cds-NP_009593.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:298365-299252:- | gene-YBR037C_PE2H3 | rna-NM_001178385.1_PE2H3 | cds-NP_009593.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:296041-296928:- | gene-YBR037C_PE2H4 | rna-NM_001178385.1_PE2H4 | cds-NP_009593.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:310565-311452:- | gene-YBR037C_S288C | rna-NM_001178385.1_S288C | cds-NP_009593.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:166092-166979:+ | gene-YBR037C_SA1 | rna-NM_001178385.1_SA1 | cds-NP_009593.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:308068-308955:- | gene-YBR037C_ThermosaccDry | rna-NM_001178385.1_ThermosaccDry | cds-NP_009593.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:289718-290605:- | gene-YBR037C_VR1 | rna-NM_001178385.1_VR1 | cds-NP_009593.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:283792-284679:- | gene-YBR037C_ZTW1 | rna-NM_001178385.1_ZTW1 | cds-NP_009593.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:320012-320917:- | gene-YBR037C_Sparadoxus | rna-NM_001178385.1_Sparadoxus | cds-NP_009593.1_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |