Gene name: SCM3
Reference locus (S288C): YDL139C
Gene biotype: protein_coding
Description: Protein SCM3; Nonhistone component of centromeric chromatin; binds to histone H3 variant, Cse4p, and recruits it to centromeres; involved in the assembly and maintenance of Cse4-H4 at centromeres; required for kinetochore assembly and G2/M progression; may protect Cse4p from ubiquitination; homolog of mammalian HJURP
Top 10 interactors (score): CSE4 (0.999); CBF2 (0.991); HHF1 (0.974); HHT2 (0.96); PSH1 (0.934); HHT1 (0.933); HHF2 (0.908); CHZ1 (0.777); NAP1 (0.749); CEP3 (0.69); SPC105 (0.671); MCM22 (0.654); CTF19 (0.632); CBF1 (0.631); MAD2 (0.616); ASF1 (0.599); HTZ1 (0.574); MAD3 (0.572); VPS75 (0.567); HTA2 (0.564)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:195822-196493:- | gene-YDL139C_AKU4011 | rna-NM_001180199.1_AKU4011 | cds-NP_010142.2_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:353276-353947:+ | gene-YDL139C_BG1 | rna-NM_001180199.1_BG1 | cds-NP_010142.2_BG1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:211841-212512:- | gene-YDL139C_Bruggeman | rna-NM_001180199.1_Bruggeman | cds-NP_010142.2_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:210162-210833:- | gene-YDL139C_CAT1 | rna-NM_001180199.1_CAT1 | cds-NP_010142.2_CAT1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:193778-194449:- | gene-YDL139C_CBS1585 | rna-NM_001180199.1_CBS1585 | cds-NP_010142.2_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:210766-211437:- | gene-YDL139C_CBS436 | rna-NM_001180199.1_CBS436 | cds-NP_010142.2_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:193075-193746:- | gene-YDL139C_CBS6412 | rna-NM_001180199.1_CBS6412 | cds-NP_010142.2_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:212245-212916:- | gene-YDL139C_CBS6413 | rna-NM_001180199.1_CBS6413 | cds-NP_010142.2_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:210027-210698:- | gene-YDL139C_CENPK1137D | rna-NM_001180199.1_CENPK1137D | cds-NP_010142.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:207042-207713:- | gene-YDL139C_EthanolRed | rna-NM_001180199.1_EthanolRed | cds-NP_010142.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:212574-213245:- | gene-YDL139C_FaliES1 | rna-NM_001180199.1_FaliES1 | cds-NP_010142.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:6300-6971:+ | gene-YDL139C_JAY291 | rna-NM_001180199.1_JAY291 | cds-NP_010142.2_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:210952-211623:- | gene-YDL139C_MUCL30387 | rna-NM_001180199.1_MUCL30387 | cds-NP_010142.2_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:201813-202484:- | gene-YDL139C_MUCL30388 | rna-NM_001180199.1_MUCL30388 | cds-NP_010142.2_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:194940-195611:- | gene-YDL139C_MUCL39482 | rna-NM_001180199.1_MUCL39482 | cds-NP_010142.2_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000205.1:6261-6932:+ | gene-YDL139C_MUCL42920 | rna-NM_001180199.1_MUCL42920 | cds-NP_010142.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:211298-211969:- | gene-YDL139C_NCIM3186 | rna-NM_001180199.1_NCIM3186 | cds-NP_010142.2_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:194910-195581:- | gene-YDL139C_NCYC1407 | rna-NM_001180199.1_NCYC1407 | cds-NP_010142.2_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:202184-202855:- | gene-YDL139C_PE2H3 | rna-NM_001180199.1_PE2H3 | cds-NP_010142.2_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:202188-202859:- | gene-YDL139C_PE2H4 | rna-NM_001180199.1_PE2H4 | cds-NP_010142.2_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:211375-212046:- | gene-YDL139C_S288C | rna-NM_001180199.1_S288C | cds-NP_010142.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:76922-77593:- | gene-YDL139C_SA1 | rna-NM_001180199.1_SA1 | cds-NP_010142.2_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:212335-213006:- | gene-YDL139C_ThermosaccDry | rna-NM_001180199.1_ThermosaccDry | cds-NP_010142.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:213148-213819:- | gene-YDL139C_VR1 | rna-NM_001180199.1_VR1 | cds-NP_010142.2_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:210457-211127:- | gene-YDL139C_ZTW1 | rna-NM_001180199.1_ZTW1 | cds-NP_010142.2_ZTW1 | 99.1 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:212550-213221:- | gene-YDL139C_Sparadoxus | rna-NM_001180199.1_Sparadoxus | cds-NP_010142.2_Sparadoxus | 87.8 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |