SCL1 (YGL011C)


Gene profile

Gene name: SCL1
Reference locus (S288C): YGL011C
Gene biotype: protein_coding

Description: Alpha 1 subunit of the 20S proteasome; involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria; Belongs to the peptidase T1A family

Top 10 interactors (score): RPT4 (0.999); RPN7 (0.999); PRE2 (0.999); RPN12 (0.999); RPN5 (0.999); RPT1 (0.999); RPN6 (0.999); RPN2 (0.999); PRE7 (0.999); PRE1 (0.999); PUP3 (0.999); PRE4 (0.999); RPT3 (0.999); PRE10 (0.999); RPT6 (0.999); RPN3 (0.999); PRE8 (0.999); PRE5 (0.999); RPN1 (0.999); RPT2 (0.999)

Homologues (species, bitscore): PSMA6 (Homo sapiens, 273.9); Psma6 (Mus musculus, 274.6); zgc:92716 (Danio rerio, 276.6); psma6 (Xenopus tropicalis, 270.0); Prosalpha1 (Drosophila melanogaster, 246.9); pas-1 (Caenorhabditis elegans, 241.5); At5g35590 (Arabidopsis thaliana, 253.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:476540-477298:- gene-YGL011C_AKU4011 rna-NM_001180876.3_AKU4011 cds-NP_011504.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000060.1:98812-99570:+ gene-YGL011C_BG1 rna-NM_001180876.3_BG1 cds-NP_011504.3_BG1 99.2 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:477509-478267:- gene-YGL011C_Bruggeman rna-NM_001180876.3_Bruggeman cds-NP_011504.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:475802-476560:- gene-YGL011C_CAT1 rna-NM_001180876.3_CAT1 cds-NP_011504.3_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:478011-478769:- gene-YGL011C_CBS1585 rna-NM_001180876.3_CBS1585 cds-NP_011504.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:472391-473149:- gene-YGL011C_CBS436 rna-NM_001180876.3_CBS436 cds-NP_011504.3_CBS436 99.2 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:470626-471384:- gene-YGL011C_CBS6412 rna-NM_001180876.3_CBS6412 cds-NP_011504.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:474682-475440:- gene-YGL011C_CBS6413 rna-NM_001180876.3_CBS6413 cds-NP_011504.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:474310-475068:- gene-YGL011C_CENPK1137D rna-NM_001180876.3_CENPK1137D cds-NP_011504.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:464907-465665:- gene-YGL011C_EthanolRed rna-NM_001180876.3_EthanolRed cds-NP_011504.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:468163-468921:- gene-YGL011C_FaliES1 rna-NM_001180876.3_FaliES1 cds-NP_011504.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000020.1:6798-7556:- gene-YGL011C_JAY291 rna-NM_001180876.3_JAY291 cds-NP_011504.3_JAY291 99.2 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:474732-475490:- gene-YGL011C_MUCL30387 rna-NM_001180876.3_MUCL30387 cds-NP_011504.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:477281-478039:- gene-YGL011C_MUCL30388 rna-NM_001180876.3_MUCL30388 cds-NP_011504.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:473850-474608:- gene-YGL011C_MUCL39482 rna-NM_001180876.3_MUCL39482 cds-NP_011504.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:483287-484045:- gene-YGL011C_MUCL42920 rna-NM_001180876.3_MUCL42920 cds-NP_011504.3_MUCL42920 99.3 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:474489-475247:- gene-YGL011C_NCIM3186 rna-NM_001180876.3_NCIM3186 cds-NP_011504.3_NCIM3186 99.3 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:467872-468630:- gene-YGL011C_NCYC1407 rna-NM_001180876.3_NCYC1407 cds-NP_011504.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:470566-471324:- gene-YGL011C_PE2H3 rna-NM_001180876.3_PE2H3 cds-NP_011504.3_PE2H3 99.2 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:475616-476374:- gene-YGL011C_PE2H4 rna-NM_001180876.3_PE2H4 cds-NP_011504.3_PE2H4 99.2 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:474489-475247:- gene-YGL011C_S288C rna-NM_001180876.3_S288C cds-NP_011504.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000021.1:80337-81095:+ gene-YGL011C_SA1 rna-NM_001180876.3_SA1 cds-NP_011504.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:487488-488246:- gene-YGL011C_ThermosaccDry rna-NM_001180876.3_ThermosaccDry cds-NP_011504.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:577573-578331:- gene-YGL011C_VR1 rna-NM_001180876.3_VR1 cds-NP_011504.3_VR1 99.2 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:466094-466852:- gene-YGL011C_ZTW1 rna-NM_001180876.3_ZTW1 cds-NP_011504.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:475638-476396:- gene-YGL011C_Sparadoxus rna-NM_001180876.3_Sparadoxus cds-NP_011504.3_Sparadoxus 91.9 100.0 Verified 1 1 1 False True False False False

Additional files