Gene name: SCD6
Reference locus (S288C): YPR129W
Gene biotype: protein_coding
Description: Protein SCD6; Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1; forms cytoplasmic foci upon DNA replication stress
Top 10 interactors (score): DCP1 (0.999); DCP2 (0.999); DHH1 (0.999); PAB1 (0.998); EDC3 (0.998); CDC33 (0.99); LSM1 (0.988); XRN1 (0.987); PAT1 (0.956); LSM2 (0.938); TIF4631 (0.932); HMT1 (0.928); LSM4 (0.927); PBP1 (0.914); LSM5 (0.903); PUF3 (0.9); DED1 (0.893); CDC39 (0.889); TIF4632 (0.889); LSM3 (0.881)
Homologues (species, bitscore): LSM14B (Homo sapiens, 100.1); Lsm14b (Mus musculus, 103.2); lsm14ab (Danio rerio, 101.7); lsm14a (Xenopus tropicalis, 91.3); tral (Drosophila melanogaster, 71.2); car-1 (Caenorhabditis elegans, 117.1); DCP5 (Arabidopsis thaliana, 69.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:764372-765421:+ | gene-YPR129W_AKU4011 | rna-NM_001184226.1_AKU4011 | cds-NP_015454.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:131944-132993:- | gene-YPR129W_BG1 | rna-NM_001184226.1_BG1 | cds-NP_015454.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:845023-846072:+ | gene-YPR129W_Bruggeman | rna-NM_001184226.1_Bruggeman | cds-NP_015454.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:886947-887996:+ | gene-YPR129W_CAT1 | rna-NM_001184226.1_CAT1 | cds-NP_015454.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:768629-769678:+ | gene-YPR129W_CBS1585 | rna-NM_001184226.1_CBS1585 | cds-NP_015454.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:783103-784152:+ | gene-YPR129W_CBS436 | rna-NM_001184226.1_CBS436 | cds-NP_015454.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:771352-772401:+ | gene-YPR129W_CBS6412 | rna-NM_001184226.1_CBS6412 | cds-NP_015454.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:766075-767124:+ | gene-YPR129W_CBS6413 | rna-NM_001184226.1_CBS6413 | cds-NP_015454.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:792742-793791:+ | gene-YPR129W_CENPK1137D | rna-NM_001184226.1_CENPK1137D | cds-NP_015454.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1086539-1087588:+ | gene-YPR129W_EthanolRed | rna-NM_001184226.1_EthanolRed | cds-NP_015454.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:766086-767135:+ | gene-YPR129W_FaliES1 | rna-NM_001184226.1_FaliES1 | cds-NP_015454.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000036.1:23363-24412:+ | gene-YPR129W_JAY291 | rna-NM_001184226.1_JAY291 | cds-NP_015454.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:785214-786263:+ | gene-YPR129W_MUCL30387 | rna-NM_001184226.1_MUCL30387 | cds-NP_015454.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:785179-786228:+ | gene-YPR129W_MUCL30388 | rna-NM_001184226.1_MUCL30388 | cds-NP_015454.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:761136-762185:+ | gene-YPR129W_MUCL39482 | rna-NM_001184226.1_MUCL39482 | cds-NP_015454.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:824934-825983:+ | gene-YPR129W_MUCL42920 | rna-NM_001184226.1_MUCL42920 | cds-NP_015454.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:792670-793719:+ | gene-YPR129W_NCIM3186 | rna-NM_001184226.1_NCIM3186 | cds-NP_015454.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:769729-770778:+ | gene-YPR129W_NCYC1407 | rna-NM_001184226.1_NCYC1407 | cds-NP_015454.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:776451-777500:+ | gene-YPR129W_PE2H3 | rna-NM_001184226.1_PE2H3 | cds-NP_015454.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:776099-777148:+ | gene-YPR129W_PE2H4 | rna-NM_001184226.1_PE2H4 | cds-NP_015454.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:792687-793736:+ | gene-YPR129W_S288C | rna-NM_001184226.1_S288C | cds-NP_015454.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000028.1:90483-91532:+ | gene-YPR129W_SA1 | rna-NM_001184226.1_SA1 | cds-NP_015454.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:765531-766580:+ | gene-YPR129W_ThermosaccDry | rna-NM_001184226.1_ThermosaccDry | cds-NP_015454.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:787356-788405:+ | gene-YPR129W_VR1 | rna-NM_001184226.1_VR1 | cds-NP_015454.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:769286-770335:+ | gene-YPR129W_ZTW1 | rna-NM_001184226.1_ZTW1 | cds-NP_015454.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:771255-772292:+ | gene-YPR129W_Sparadoxus | rna-NM_001184226.1_Sparadoxus | cds-NP_015454.1_Sparadoxus | 89.5 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |