SBP1 (YHL034C)


Gene profile

Gene name: SBP1
Reference locus (S288C): YHL034C
Gene biotype: protein_coding

Description: Single-stranded nucleic acid-binding protein; Protein that binds eIF4G and has a role in repression of translation; has an RGG motif; found in cytoplasmic P bodies; binds to mRNAs under glucose starvation stress, most often in the 5' UTR; found associated with small nucleolar RNAs snR10 and snR11; SBP1 has a paralog, RNP1, that arose from the whole genome duplication; Belongs to the RRM GAR family

Top 10 interactors (score): PAB1 (0.912); TIF4631 (0.889); HMT1 (0.874); CBF5 (0.846); SCD6 (0.797); GIS2 (0.792); CDC33 (0.779); TIF4632 (0.757); EAP1 (0.75); SLF1 (0.746); SRO9 (0.729); DHH1 (0.713); CBC2 (0.669); TEF2 (0.628); DCP2 (0.627); SCP160 (0.617); PUB1 (0.616); EDC3 (0.615); MPT5 (0.607); CAF20 (0.606)

Homologues (species, bitscore): NCL (Homo sapiens, 80.1); Ncl (Mus musculus, 81.6); ncl (Danio rerio, 75.5); ncl (Xenopus tropicalis, 50.4); sqd (Drosophila melanogaster, 63.5); hrp-2 (Caenorhabditis elegans, 54.3); AT5G40490 (Arabidopsis thaliana, 50.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:28046-28930:- gene-YHL034C_AKU4011 rna-NM_001179114.1_AKU4011 cds-NP_011829.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000180.1:47896-48780:+ gene-YHL034C_BG1 rna-NM_001179114.1_BG1 cds-NP_011829.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:34708-35592:- gene-YHL034C_Bruggeman rna-NM_001179114.1_Bruggeman cds-NP_011829.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:28963-29847:- gene-YHL034C_CAT1 rna-NM_001179114.1_CAT1 cds-NP_011829.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:28649-29533:- gene-YHL034C_CBS1585 rna-NM_001179114.1_CBS1585 cds-NP_011829.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:21233-22117:- gene-YHL034C_CBS436 rna-NM_001179114.1_CBS436 cds-NP_011829.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:28598-29482:- gene-YHL034C_CBS6412 rna-NM_001179114.1_CBS6412 cds-NP_011829.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:28064-28948:- gene-YHL034C_CBS6413 rna-NM_001179114.1_CBS6413 cds-NP_011829.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:26358-27242:- gene-YHL034C_CENPK1137D rna-NM_001179114.1_CENPK1137D cds-NP_011829.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:28274-29158:- gene-YHL034C_EthanolRed rna-NM_001179114.1_EthanolRed cds-NP_011829.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:28598-29482:- gene-YHL034C_FaliES1 rna-NM_001179114.1_FaliES1 cds-NP_011829.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000157.1:20555-21439:- gene-YHL034C_JAY291 rna-NM_001179114.1_JAY291 cds-NP_011829.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:30542-31426:- gene-YHL034C_MUCL30387 rna-NM_001179114.1_MUCL30387 cds-NP_011829.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:32381-33265:- gene-YHL034C_MUCL30388 rna-NM_001179114.1_MUCL30388 cds-NP_011829.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:27640-28524:- gene-YHL034C_MUCL39482 rna-NM_001179114.1_MUCL39482 cds-NP_011829.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:31611-32495:- gene-YHL034C_MUCL42920 rna-NM_001179114.1_MUCL42920 cds-NP_011829.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:33075-33959:- gene-YHL034C_NCIM3186 rna-NM_001179114.1_NCIM3186 cds-NP_011829.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:27126-28010:- gene-YHL034C_NCYC1407 rna-NM_001179114.1_NCYC1407 cds-NP_011829.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:23417-24301:- gene-YHL034C_PE2H3 rna-NM_001179114.1_PE2H3 cds-NP_011829.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:30794-31678:- gene-YHL034C_PE2H4 rna-NM_001179114.1_PE2H4 cds-NP_011829.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:33193-34077:- gene-YHL034C_S288C rna-NM_001179114.1_S288C cds-NP_011829.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:17482-18366:- gene-YHL034C_SA1 rna-NM_001179114.1_SA1 cds-NP_011829.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:29687-30571:- gene-YHL034C_ThermosaccDry rna-NM_001179114.1_ThermosaccDry cds-NP_011829.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:34397-35281:- gene-YHL034C_VR1 rna-NM_001179114.1_VR1 cds-NP_011829.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:20902-21786:- gene-YHL034C_ZTW1 rna-NM_001179114.1_ZTW1 cds-NP_011829.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:27232-28116:- gene-YHL034C_Sparadoxus rna-NM_001179114.1_Sparadoxus cds-NP_011829.1_Sparadoxus 93.2 100.0 Verified 1 1 1 False True False False False

Additional files