SBA1 (YKL117W)


Gene profile

Gene name: SBA1
Reference locus (S288C): YKL117W
Gene biotype: protein_coding

Description: Co-chaperone protein SBA1; Co-chaperone that binds and regulates Hsp90 family chaperones; plays a role in determining prion variants; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins, and like p23 can regulate telomerase activity; protein abundance increases in response to DNA replication stress; Belongs to the p23/wos2 family

Top 10 interactors (score): HSC82 (0.999); HSP82 (0.999); CPR6 (0.999); STI1 (0.999); AHA1 (0.999); CPR7 (0.992); HCH1 (0.992); SIS1 (0.979); HSP104 (0.975); SSE1 (0.974); PPT1 (0.974); CDC37 (0.971); ACB1 (0.966); CNS1 (0.942); SSE2 (0.937); HSP78 (0.933); HDA1 (0.924); CDC48 (0.92); EST2 (0.919); CAM1 (0.916)

Homologues (species, bitscore): PTGES3 (Homo sapiens, 60.1); Ptges3 (Mus musculus, 58.5); ptges3a (Danio rerio, 53.9); PTPLAD1 (Xenopus tropicalis, 52.8); ZC395.10 (Caenorhabditis elegans, 79.0); AT4G02450 (Arabidopsis thaliana, 98.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:206900-207550:+ gene-YKL117W_AKU4011 rna-NM_001179683.1_AKU4011 cds-NP_012805.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:184022-184672:+ gene-YKL117W_BG1 rna-NM_001179683.1_BG1 cds-NP_012805.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:224814-225464:+ gene-YKL117W_Bruggeman rna-NM_001179683.1_Bruggeman cds-NP_012805.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:219868-220518:+ gene-YKL117W_CAT1 rna-NM_001179683.1_CAT1 cds-NP_012805.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:219132-219782:+ gene-YKL117W_CBS1585 rna-NM_001179683.1_CBS1585 cds-NP_012805.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:217720-218370:+ gene-YKL117W_CBS436 rna-NM_001179683.1_CBS436 cds-NP_012805.1_CBS436 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:203762-204412:+ gene-YKL117W_CBS6412 rna-NM_001179683.1_CBS6412 cds-NP_012805.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:219596-220246:+ gene-YKL117W_CBS6413 rna-NM_001179683.1_CBS6413 cds-NP_012805.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:219972-220622:+ gene-YKL117W_CENPK1137D rna-NM_001179683.1_CENPK1137D cds-NP_012805.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:217631-218227:+ gene-YKL117W_EthanolRed rna-NM_001179683.1_EthanolRed cds-NP_012805.1_EthanolRed 91.2 91.7 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:218444-219040:+ gene-YKL117W_FaliES1 rna-NM_001179683.1_FaliES1 cds-NP_012805.1_FaliES1 91.2 91.7 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:40738-41388:+ gene-YKL117W_JAY291 rna-NM_001179683.1_JAY291 cds-NP_012805.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:226635-227276:+ gene-YKL117W_MUCL30387 rna-NM_001179683.1_MUCL30387 cds-NP_012805.1_MUCL30387 98.0 98.6 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:221006-221656:+ gene-YKL117W_MUCL30388 rna-NM_001179683.1_MUCL30388 cds-NP_012805.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:218927-219577:+ gene-YKL117W_MUCL39482 rna-NM_001179683.1_MUCL39482 cds-NP_012805.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:223302-223952:+ gene-YKL117W_MUCL42920 rna-NM_001179683.1_MUCL42920 cds-NP_012805.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:220313-220963:+ gene-YKL117W_NCIM3186 rna-NM_001179683.1_NCIM3186 cds-NP_012805.1_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:219108-219758:+ gene-YKL117W_NCYC1407 rna-NM_001179683.1_NCYC1407 cds-NP_012805.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:226208-226858:+ gene-YKL117W_PE2H3 rna-NM_001179683.1_PE2H3 cds-NP_012805.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:222491-223141:+ gene-YKL117W_PE2H4 rna-NM_001179683.1_PE2H4 cds-NP_012805.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:220324-220974:+ gene-YKL117W_S288C rna-NM_001179683.1_S288C cds-NP_012805.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:136448-137098:+ gene-YKL117W_SA1 rna-NM_001179683.1_SA1 cds-NP_012805.1_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:219144-219740:+ gene-YKL117W_ThermosaccDry rna-NM_001179683.1_ThermosaccDry cds-NP_012805.1_ThermosaccDry 91.2 91.7 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:218459-219109:+ gene-YKL117W_VR1 rna-NM_001179683.1_VR1 cds-NP_012805.1_VR1 99.0 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:217673-218314:+ gene-YKL117W_ZTW1 rna-NM_001179683.1_ZTW1 cds-NP_012805.1_ZTW1 97.6 98.6 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:234589-235293:+ gene-YKL117W_Sparadoxus rna-NM_001179683.1_Sparadoxus cds-NP_012805.1_Sparadoxus 86.0 100.0 Verified 1 1 1 False True False False False

Additional files