Gene name: SAT4
Reference locus (S288C): YCR008W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase HAL4/SAT4; Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion
Top 10 interactors (score): PPZ1 (0.934); TRK1 (0.919); TRK2 (0.887); MEC1 (0.875); SIS2 (0.837); TEL1 (0.793); CDC21 (0.752); DPB11 (0.748); TOF1 (0.742); YDL026W (0.712); YDR249C (0.712); CSM3 (0.711); HAL5 (0.704); CDC45 (0.698); RAD24 (0.697); HAL1 (0.69); RVS161 (0.689); RAD51 (0.679); NHA1 (0.654); SKY1 (0.648)
Homologues (species, bitscore): CHEK1 (Homo sapiens, 139.0); Chek1 (Mus musculus, 139.0); chek1 (Danio rerio, 137.1); chek1 (Xenopus tropicalis, 140.6); AMPKalpha (Drosophila melanogaster, 124.8); kin-33 (Caenorhabditis elegans, 135.6); OST1 (Arabidopsis thaliana, 127.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:122848-124659:+ | gene-YCR008W_AKU4011 | rna-NM_001178721.1_AKU4011 | cds-NP_009934.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000178.1:21349-23160:- | gene-YCR008W_BG1 | rna-NM_001178721.1_BG1 | cds-NP_009934.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:118657-120468:+ | gene-YCR008W_Bruggeman | rna-NM_001178721.1_Bruggeman | cds-NP_009934.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:129059-130870:+ | gene-YCR008W_CAT1 | rna-NM_001178721.1_CAT1 | cds-NP_009934.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:123497-125308:+ | gene-YCR008W_CBS1585 | rna-NM_001178721.1_CBS1585 | cds-NP_009934.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:128753-130564:+ | gene-YCR008W_CBS436 | rna-NM_001178721.1_CBS436 | cds-NP_009934.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:110958-112769:+ | gene-YCR008W_CBS6412 | rna-NM_001178721.1_CBS6412 | cds-NP_009934.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:122804-124615:+ | gene-YCR008W_CBS6413 | rna-NM_001178721.1_CBS6413 | cds-NP_009934.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:133948-135759:+ | gene-YCR008W_CENPK1137D | rna-NM_001178721.1_CENPK1137D | cds-NP_009934.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:120866-122677:+ | gene-YCR008W_EthanolRed | rna-NM_001178721.1_EthanolRed | cds-NP_009934.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:123164-124975:+ | gene-YCR008W_FaliES1 | rna-NM_001178721.1_FaliES1 | cds-NP_009934.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000126.1:37332-39143:+ | gene-YCR008W_JAY291 | rna-NM_001178721.1_JAY291 | cds-NP_009934.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:116459-118270:+ | gene-YCR008W_MUCL30387 | rna-NM_001178721.1_MUCL30387 | cds-NP_009934.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:115434-117245:+ | gene-YCR008W_MUCL30388 | rna-NM_001178721.1_MUCL30388 | cds-NP_009934.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:123914-125725:+ | gene-YCR008W_MUCL39482 | rna-NM_001178721.1_MUCL39482 | cds-NP_009934.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:119150-120961:+ | gene-YCR008W_MUCL42920 | rna-NM_001178721.1_MUCL42920 | cds-NP_009934.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:128102-129913:+ | gene-YCR008W_NCIM3186 | rna-NM_001178721.1_NCIM3186 | cds-NP_009934.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:124397-126208:+ | gene-YCR008W_NCYC1407 | rna-NM_001178721.1_NCYC1407 | cds-NP_009934.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:128591-130402:+ | gene-YCR008W_PE2H3 | rna-NM_001178721.1_PE2H3 | cds-NP_009934.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:128529-130340:+ | gene-YCR008W_PE2H4 | rna-NM_001178721.1_PE2H4 | cds-NP_009934.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:128470-130281:+ | gene-YCR008W_S288C | rna-NM_001178721.1_S288C | cds-NP_009934.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000073.1:21387-23198:- | gene-YCR008W_SA1 | rna-NM_001178721.1_SA1 | cds-NP_009934.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:123732-125543:+ | gene-YCR008W_ThermosaccDry | rna-NM_001178721.1_ThermosaccDry | cds-NP_009934.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:134658-136469:+ | gene-YCR008W_VR1 | rna-NM_001178721.1_VR1 | cds-NP_009934.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:122667-124478:+ | gene-YCR008W_ZTW1 | rna-NM_001178721.1_ZTW1 | cds-NP_009934.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:154803-156614:+ | gene-YCR008W_Sparadoxus | rna-NM_001178721.1_Sparadoxus | cds-NP_009934.1_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |