SAS3 (YBL052C)


Gene profile

Gene name: SAS3
Reference locus (S288C): YBL052C
Gene biotype: protein_coding

Description: Histone acetyltransferase catalytic subunit of NuA3 complex; acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal; Belongs to the MYST (SAS/MOZ) family

Top 10 interactors (score): GCN5 (0.999); NTO1 (0.999); EAF6 (0.999); YNG1 (0.998); TAF14 (0.995); TRA1 (0.993); PDP3 (0.991); RVB1 (0.99); EPL1 (0.985); SWD3 (0.981); HTZ1 (0.98); HHT2 (0.969); YNG2 (0.957); HHF1 (0.957); HTA2 (0.953); SWR1 (0.952); RVB2 (0.948); HHT1 (0.94); HTB1 (0.933); RPD3 (0.932)

Homologues (species, bitscore): KAT5 (Homo sapiens, 263.8); Kat5 (Mus musculus, 263.5); htatip (Danio rerio, 264.6); kat7 (Xenopus tropicalis, 258.8); enok (Drosophila melanogaster, 266.2); mys-1 (Caenorhabditis elegans, 251.9); HAG5 (Arabidopsis thaliana, 238.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:112959-115454:- gene-YBL052C_AKU4011 rna-NM_001178292.1_AKU4011 cds-NP_009501.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:103809-106304:- gene-YBL052C_BG1 rna-NM_001178292.1_BG1 cds-NP_009501.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:113572-116070:- gene-YBL052C_Bruggeman rna-NM_001178292.1_Bruggeman cds-NP_009501.1_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:116209-118704:- gene-YBL052C_CAT1 rna-NM_001178292.1_CAT1 cds-NP_009501.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:105526-108021:- gene-YBL052C_CBS1585 rna-NM_001178292.1_CBS1585 cds-NP_009501.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:114031-116529:- gene-YBL052C_CBS436 rna-NM_001178292.1_CBS436 cds-NP_009501.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:104031-106526:- gene-YBL052C_CBS6412 rna-NM_001178292.1_CBS6412 cds-NP_009501.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:111104-113599:- gene-YBL052C_CBS6413 rna-NM_001178292.1_CBS6413 cds-NP_009501.1_CBS6413 99.0 100.0 Unannotated 1 1 0 False False False False True
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:113144-115639:- gene-YBL052C_CENPK1137D rna-NM_001178292.1_CENPK1137D cds-NP_009501.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:126959-129454:- gene-YBL052C_EthanolRed rna-NM_001178292.1_EthanolRed cds-NP_009501.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:127812-130307:- gene-YBL052C_FaliES1 rna-NM_001178292.1_FaliES1 cds-NP_009501.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000072.1:30426-32924:- gene-YBL052C_JAY291 rna-NM_001178292.1_JAY291 cds-NP_009501.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:112945-115443:- gene-YBL052C_MUCL30387 rna-NM_001178292.1_MUCL30387 cds-NP_009501.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:114223-116721:- gene-YBL052C_MUCL30388 rna-NM_001178292.1_MUCL30388 cds-NP_009501.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:105706-108201:- gene-YBL052C_MUCL39482 rna-NM_001178292.1_MUCL39482 cds-NP_009501.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:112541-115039:- gene-YBL052C_MUCL42920 rna-NM_001178292.1_MUCL42920 cds-NP_009501.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:119176-121671:- gene-YBL052C_NCIM3186 rna-NM_001178292.1_NCIM3186 cds-NP_009501.1_NCIM3186 96.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:106849-109344:- gene-YBL052C_NCYC1407 rna-NM_001178292.1_NCYC1407 cds-NP_009501.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:113102-115600:- gene-YBL052C_PE2H3 rna-NM_001178292.1_PE2H3 cds-NP_009501.1_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:110746-113244:- gene-YBL052C_PE2H4 rna-NM_001178292.1_PE2H4 cds-NP_009501.1_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:119379-121874:- gene-YBL052C_S288C rna-NM_001178292.1_S288C cds-NP_009501.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:3957-6455:- gene-YBL052C_SA1 rna-NM_001178292.1_SA1 cds-NP_009501.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:127773-130268:- gene-YBL052C_ThermosaccDry rna-NM_001178292.1_ThermosaccDry cds-NP_009501.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:109938-112436:- gene-YBL052C_VR1 rna-NM_001178292.1_VR1 cds-NP_009501.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:104483-106979:- gene-YBL052C_ZTW1 rna-NM_001178292.1_ZTW1 cds-NP_009501.1_ZTW1 99.1 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:139149-141665:- gene-YBL052C_Sparadoxus rna-NM_001178292.1_Sparadoxus cds-NP_009501.1_Sparadoxus 85.3 99.3 Verified 1 1 1 False True False False False

Additional files