Gene name: SAS2
Reference locus (S288C): YMR127C
Gene biotype: protein_coding
Description: Histone acetyltransferase (HAT) catalytic subunit of the SAS complex; acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family; other members are Sas4p and Sas5p
Top 10 interactors (score): SAS5 (0.999); SAS4 (0.999); GCN5 (0.996); TRA1 (0.99); HHF1 (0.99); EPL1 (0.984); RVB1 (0.984); EAF3 (0.982); SWC4 (0.975); ASF1 (0.972); YNG2 (0.97); EAF6 (0.966); ARP4 (0.963); HHF2 (0.962); HTZ1 (0.962); SIR2 (0.962); RPD3 (0.955); SIR3 (0.947); NGG1 (0.944); ACT1 (0.941)
Homologues (species, bitscore): KAT8 (Homo sapiens, 160.2); Kat8 (Mus musculus, 159.8); kat8 (Danio rerio, 161.0); kat8 (Xenopus tropicalis, 160.6); mof (Drosophila melanogaster, 164.5); mys-2 (Caenorhabditis elegans, 152.1); HAG4 (Arabidopsis thaliana, 146.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:561828-562844:- | gene-YMR127C_AKU4011 | rna-NM_001182628.1_AKU4011 | cds-NP_013846.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:109689-110705:+ | gene-YMR127C_BG1 | rna-NM_001182628.1_BG1 | cds-NP_013846.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:505009-506025:- | gene-YMR127C_Bruggeman | rna-NM_001182628.1_Bruggeman | cds-NP_013846.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:507223-508239:- | gene-YMR127C_CAT1 | rna-NM_001182628.1_CAT1 | cds-NP_013846.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:494751-495767:- | gene-YMR127C_CBS1585 | rna-NM_001182628.1_CBS1585 | cds-NP_013846.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:498624-499640:- | gene-YMR127C_CBS436 | rna-NM_001182628.1_CBS436 | cds-NP_013846.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:607744-608760:- | gene-YMR127C_CBS6412 | rna-NM_001182628.1_CBS6412 | cds-NP_013846.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:493311-494327:- | gene-YMR127C_CBS6413 | rna-NM_001182628.1_CBS6413 | cds-NP_013846.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:516843-517859:- | gene-YMR127C_CENPK1137D | rna-NM_001182628.1_CENPK1137D | cds-NP_013846.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:492941-493957:- | gene-YMR127C_EthanolRed | rna-NM_001182628.1_EthanolRed | cds-NP_013846.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:498882-499898:- | gene-YMR127C_FaliES1 | rna-NM_001182628.1_FaliES1 | cds-NP_013846.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000294.1:27092-28108:+ | gene-YMR127C_JAY291 | rna-NM_001182628.1_JAY291 | cds-NP_013846.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:499734-500750:- | gene-YMR127C_MUCL30387 | rna-NM_001182628.1_MUCL30387 | cds-NP_013846.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:505260-506276:- | gene-YMR127C_MUCL30388 | rna-NM_001182628.1_MUCL30388 | cds-NP_013846.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:495452-496468:- | gene-YMR127C_MUCL39482 | rna-NM_001182628.1_MUCL39482 | cds-NP_013846.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:501747-502763:- | gene-YMR127C_MUCL42920 | rna-NM_001182628.1_MUCL42920 | cds-NP_013846.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:522283-523299:- | gene-YMR127C_NCIM3186 | rna-NM_001182628.1_NCIM3186 | cds-NP_013846.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:495090-496106:- | gene-YMR127C_NCYC1407 | rna-NM_001182628.1_NCYC1407 | cds-NP_013846.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:505526-506542:- | gene-YMR127C_PE2H3 | rna-NM_001182628.1_PE2H3 | cds-NP_013846.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:505980-506996:- | gene-YMR127C_PE2H4 | rna-NM_001182628.1_PE2H4 | cds-NP_013846.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:522329-523345:- | gene-YMR127C_S288C | rna-NM_001182628.1_S288C | cds-NP_013846.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000048.1:47930-48946:+ | gene-YMR127C_SA1 | rna-NM_001182628.1_SA1 | cds-NP_013846.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:495339-496355:- | gene-YMR127C_ThermosaccDry | rna-NM_001182628.1_ThermosaccDry | cds-NP_013846.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:508028-509044:- | gene-YMR127C_VR1 | rna-NM_001182628.1_VR1 | cds-NP_013846.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:470484-471500:- | gene-YMR127C_ZTW1 | rna-NM_001182628.1_ZTW1 | cds-NP_013846.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:506803-507819:- | gene-YMR127C_Sparadoxus | rna-NM_001182628.1_Sparadoxus | cds-NP_013846.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |