Gene name: SAR1
Reference locus (S288C): YPL218W
Gene biotype: protein_coding
Description: ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics
Top 10 interactors (score): SEC13 (0.999); SEC23 (0.999); SEC24 (0.999); SEC31 (0.999); SEC12 (0.999); SFB3 (0.998); YPT1 (0.997); SFB2 (0.996); SEC16 (0.995); SED4 (0.995); SEC17 (0.979); SEC22 (0.969); IPP1 (0.963); SEC21 (0.962); SED5 (0.961); NEL1 (0.961); BET1 (0.96); SEC1 (0.907); SEC7 (0.88); BOS1 (0.878)
Homologues (species, bitscore): SAR1B (Homo sapiens, 229.2); Sar1b (Mus musculus, 229.2); sar1ab (Danio rerio, 232.3); sar1a (Xenopus tropicalis, 226.1); Sar1 (Drosophila melanogaster, 237.3); sar-1 (Caenorhabditis elegans, 224.2); SAR1B (Arabidopsis thaliana, 243.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:116590-117300:+ | gene-YPL218W_AKU4011 | rna-NM_001184032.1_AKU4011 | cds-NP_015106.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:322347-323058:+ | gene-YPL218W_BG1 | rna-NM_001184032.1_BG1 | cds-NP_015106.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:141673-142385:+ | gene-YPL218W_Bruggeman | rna-NM_001184032.1_Bruggeman | cds-NP_015106.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:138655-139366:+ | gene-YPL218W_CAT1 | rna-NM_001184032.1_CAT1 | cds-NP_015106.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:120778-121488:+ | gene-YPL218W_CBS1585 | rna-NM_001184032.1_CBS1585 | cds-NP_015106.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:135187-135899:+ | gene-YPL218W_CBS436 | rna-NM_001184032.1_CBS436 | cds-NP_015106.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:125579-126289:+ | gene-YPL218W_CBS6412 | rna-NM_001184032.1_CBS6412 | cds-NP_015106.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:116953-117663:+ | gene-YPL218W_CBS6413 | rna-NM_001184032.1_CBS6413 | cds-NP_015106.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:138645-139355:+ | gene-YPL218W_CENPK1137D | rna-NM_001184032.1_CENPK1137D | cds-NP_015106.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:115681-116394:+ | gene-YPL218W_EthanolRed | rna-NM_001184032.1_EthanolRed | cds-NP_015106.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:122887-123600:+ | gene-YPL218W_FaliES1 | rna-NM_001184032.1_FaliES1 | cds-NP_015106.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000069.1:34730-35441:- | gene-YPL218W_JAY291 | rna-NM_001184032.1_JAY291 | cds-NP_015106.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:133756-134467:+ | gene-YPL218W_MUCL30387 | rna-NM_001184032.1_MUCL30387 | cds-NP_015106.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:131946-132658:+ | gene-YPL218W_MUCL30388 | rna-NM_001184032.1_MUCL30388 | cds-NP_015106.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:113908-114618:+ | gene-YPL218W_MUCL39482 | rna-NM_001184032.1_MUCL39482 | cds-NP_015106.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:132782-133493:+ | gene-YPL218W_MUCL42920 | rna-NM_001184032.1_MUCL42920 | cds-NP_015106.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:138681-139392:+ | gene-YPL218W_NCIM3186 | rna-NM_001184032.1_NCIM3186 | cds-NP_015106.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:120354-121064:+ | gene-YPL218W_NCYC1407 | rna-NM_001184032.1_NCYC1407 | cds-NP_015106.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:128033-128744:+ | gene-YPL218W_PE2H3 | rna-NM_001184032.1_PE2H3 | cds-NP_015106.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:127676-128387:+ | gene-YPL218W_PE2H4 | rna-NM_001184032.1_PE2H4 | cds-NP_015106.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:138698-139409:+ | gene-YPL218W_S288C | rna-NM_001184032.1_S288C | cds-NP_015106.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000095.1:34764-35474:- | gene-YPL218W_SA1 | rna-NM_001184032.1_SA1 | cds-NP_015106.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:122668-123381:+ | gene-YPL218W_ThermosaccDry | rna-NM_001184032.1_ThermosaccDry | cds-NP_015106.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:136729-137440:+ | gene-YPL218W_VR1 | rna-NM_001184032.1_VR1 | cds-NP_015106.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:122209-122920:+ | gene-YPL218W_ZTW1 | rna-NM_001184032.1_ZTW1 | cds-NP_015106.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:123798-124507:+ | gene-YPL218W_Sparadoxus | rna-NM_001184032.1_Sparadoxus | cds-NP_015106.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |