Gene name: SAM2
Reference locus (S288C): YDR502C
Gene biotype: protein_coding
Description: S-adenosylmethionine synthase 2; S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; comparative analysis suggests that a mitochondrially targeted form may result from translation starting at a non-canonical codon upstream of the annotated start codon; Belongs to the AdoMet synthase family
Top 10 interactors (score): SAM1 (0.999); MET6 (0.999); SAH1 (0.997); SAM4 (0.97); SPE2 (0.967); MHT1 (0.956); ARO8 (0.91); YKL069W (0.9); MET13 (0.89); CYS4 (0.859); STR3 (0.856); CYS3 (0.847); MET14 (0.845); MET17 (0.839); MET4 (0.797); EMG1 (0.781); MET10 (0.772); BPL1 (0.752); MET16 (0.75); YLL058W (0.749)
Homologues (species, bitscore): MAT1A (Homo sapiens, 563.9); Mat1a (Mus musculus, 564.3); mat2aa (Danio rerio, 566.6); mat1a (Xenopus tropicalis, 548.9); Sam-S (Drosophila melanogaster, 522.3); sams-3 (Caenorhabditis elegans, 529.3); MTO3 (Arabidopsis thaliana, 469.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1393295-1394449:- | gene-YDR502C_AKU4011 | rna-NM_001180810.3_AKU4011 | cds-NP_010790.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:34853-36007:- | gene-YDR502C_BG1 | rna-NM_001180810.3_BG1 | cds-NP_010790.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1424616-1425770:- | gene-YDR502C_Bruggeman | rna-NM_001180810.3_Bruggeman | cds-NP_010790.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1401795-1402949:- | gene-YDR502C_CAT1 | rna-NM_001180810.3_CAT1 | cds-NP_010790.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1387537-1388691:- | gene-YDR502C_CBS1585 | rna-NM_001180810.3_CBS1585 | cds-NP_010790.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1406892-1408046:- | gene-YDR502C_CBS436 | rna-NM_001180810.3_CBS436 | cds-NP_010790.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1383179-1384333:- | gene-YDR502C_CBS6412 | rna-NM_001180810.3_CBS6412 | cds-NP_010790.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1406194-1407348:- | gene-YDR502C_CBS6413 | rna-NM_001180810.3_CBS6413 | cds-NP_010790.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1452004-1453158:- | gene-YDR502C_CENPK1137D | rna-NM_001180810.3_CENPK1137D | cds-NP_010790.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1396584-1397738:- | gene-YDR502C_EthanolRed | rna-NM_001180810.3_EthanolRed | cds-NP_010790.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1400137-1401291:- | gene-YDR502C_FaliES1 | rna-NM_001180810.3_FaliES1 | cds-NP_010790.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:98387-99541:- | gene-YDR502C_JAY291 | rna-NM_001180810.3_JAY291 | cds-NP_010790.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1407141-1408295:- | gene-YDR502C_MUCL30387 | rna-NM_001180810.3_MUCL30387 | cds-NP_010790.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1389134-1390288:- | gene-YDR502C_MUCL30388 | rna-NM_001180810.3_MUCL30388 | cds-NP_010790.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1379022-1380176:- | gene-YDR502C_MUCL39482 | rna-NM_001180810.3_MUCL39482 | cds-NP_010790.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1321814-1322968:- | gene-YDR502C_MUCL42920 | rna-NM_001180810.3_MUCL42920 | cds-NP_010790.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1453233-1454387:- | gene-YDR502C_NCIM3186 | rna-NM_001180810.3_NCIM3186 | cds-NP_010790.3_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1392808-1393962:- | gene-YDR502C_NCYC1407 | rna-NM_001180810.3_NCYC1407 | cds-NP_010790.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1403654-1404808:- | gene-YDR502C_PE2H3 | rna-NM_001180810.3_PE2H3 | cds-NP_010790.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1409231-1410385:- | gene-YDR502C_PE2H4 | rna-NM_001180810.3_PE2H4 | cds-NP_010790.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1453310-1454464:- | gene-YDR502C_S288C | rna-NM_001180810.3_S288C | cds-NP_010790.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:162669-163823:+ | gene-YDR502C_SA1 | rna-NM_001180810.3_SA1 | cds-NP_010790.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1404359-1405513:- | gene-YDR502C_ThermosaccDry | rna-NM_001180810.3_ThermosaccDry | cds-NP_010790.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1420100-1421254:- | gene-YDR502C_VR1 | rna-NM_001180810.3_VR1 | cds-NP_010790.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:447027-448181:- | gene-YDR502C_ZTW1 | rna-NM_001180810.3_ZTW1 | cds-NP_010790.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1407234-1408388:- | gene-YDR502C_Sparadoxus | rna-NM_001180810.3_Sparadoxus | cds-NP_010790.3_Sparadoxus | 94.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |