Gene name: SAM1
Reference locus (S288C): YLR180W
Gene biotype: protein_coding
Description: S-adenosylmethionine synthase 1; S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; SAM1 has a paralog, SAM2, that arose from the whole genome duplication; Belongs to the AdoMet synthase family
Top 10 interactors (score): SAM2 (0.999); SAH1 (0.998); MET6 (0.998); SAM4 (0.977); MHT1 (0.973); SPE2 (0.952); CYS3 (0.946); ARO8 (0.907); TRP2 (0.904); YKL069W (0.9); STR3 (0.864); CYS4 (0.85); MET13 (0.833); ADO1 (0.808); MET17 (0.783); MET14 (0.748); MUP1 (0.734); SHM2 (0.725); SAM3 (0.722); TRP3 (0.717)
Homologues (species, bitscore): MAT1A (Homo sapiens, 570.1); Mat1a (Mus musculus, 566.6); mat2aa (Danio rerio, 566.6); mat1a (Xenopus tropicalis, 551.2); Sam-S (Drosophila melanogaster, 519.2); sams-4 (Caenorhabditis elegans, 540.0); MTO3 (Arabidopsis thaliana, 464.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:469390-470538:+ | gene-YLR180W_AKU4011 | rna-NM_001182067.1_AKU4011 | cds-NP_013281.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:26583-27731:+ | gene-YLR180W_BG1 | rna-NM_001182067.1_BG1 | cds-NP_013281.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:509639-510787:+ | gene-YLR180W_Bruggeman | rna-NM_001182067.1_Bruggeman | cds-NP_013281.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:509229-510377:+ | gene-YLR180W_CAT1 | rna-NM_001182067.1_CAT1 | cds-NP_013281.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:504885-506033:+ | gene-YLR180W_CBS1585 | rna-NM_001182067.1_CBS1585 | cds-NP_013281.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:495019-496167:+ | gene-YLR180W_CBS436 | rna-NM_001182067.1_CBS436 | cds-NP_013281.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:473442-474590:+ | gene-YLR180W_CBS6412 | rna-NM_001182067.1_CBS6412 | cds-NP_013281.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:505177-506325:+ | gene-YLR180W_CBS6413 | rna-NM_001182067.1_CBS6413 | cds-NP_013281.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:499914-501062:+ | gene-YLR180W_CENPK1137D | rna-NM_001182067.1_CENPK1137D | cds-NP_013281.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:468911-470059:+ | gene-YLR180W_EthanolRed | rna-NM_001182067.1_EthanolRed | cds-NP_013281.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:497838-498986:+ | gene-YLR180W_FaliES1 | rna-NM_001182067.1_FaliES1 | cds-NP_013281.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:24739-25887:+ | gene-YLR180W_JAY291 | rna-NM_001182067.1_JAY291 | cds-NP_013281.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:509660-510808:+ | gene-YLR180W_MUCL30387 | rna-NM_001182067.1_MUCL30387 | cds-NP_013281.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:514592-515740:+ | gene-YLR180W_MUCL30388 | rna-NM_001182067.1_MUCL30388 | cds-NP_013281.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:505866-507014:+ | gene-YLR180W_MUCL39482 | rna-NM_001182067.1_MUCL39482 | cds-NP_013281.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:506364-507512:+ | gene-YLR180W_MUCL42920 | rna-NM_001182067.1_MUCL42920 | cds-NP_013281.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:515236-516384:+ | gene-YLR180W_NCIM3186 | rna-NM_001182067.1_NCIM3186 | cds-NP_013281.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:498293-499441:+ | gene-YLR180W_NCYC1407 | rna-NM_001182067.1_NCYC1407 | cds-NP_013281.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:502527-503675:+ | gene-YLR180W_PE2H3 | rna-NM_001182067.1_PE2H3 | cds-NP_013281.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:502271-503419:+ | gene-YLR180W_PE2H4 | rna-NM_001182067.1_PE2H4 | cds-NP_013281.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:515262-516410:+ | gene-YLR180W_S288C | rna-NM_001182067.1_S288C | cds-NP_013281.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:24796-25944:+ | gene-YLR180W_SA1 | rna-NM_001182067.1_SA1 | cds-NP_013281.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:500341-501489:+ | gene-YLR180W_ThermosaccDry | rna-NM_001182067.1_ThermosaccDry | cds-NP_013281.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:511640-512788:+ | gene-YLR180W_VR1 | rna-NM_001182067.1_VR1 | cds-NP_013281.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:24638-25786:+ | gene-YLR180W_ZTW1 | rna-NM_001182067.1_ZTW1 | cds-NP_013281.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:486455-487603:+ | gene-YLR180W_Sparadoxus | rna-NM_001182067.1_Sparadoxus | cds-NP_013281.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |