Gene name: SAH1
Reference locus (S288C): YER043C
Gene biotype: protein_coding
Description: Adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase; catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor; regulates cellular lipid homoeostasis by regulating phosphatidylcholine(PC)synthesis and triacylglycerol (TG) levels
Top 10 interactors (score): MET6 (0.999); SAM1 (0.998); SAM2 (0.997); ADO1 (0.997); CYS4 (0.988); STR3 (0.983); SFA1 (0.978); BOR1 (0.972); ADE12 (0.969); CYS3 (0.967); ADH4 (0.962); APE4 (0.961); SAM4 (0.956); MHT1 (0.954); MET17 (0.947); STR2 (0.938); YLL058W (0.938); IRC7 (0.934); YML082W (0.934); MCY1 (0.914)
Homologues (species, bitscore): AHCY (Homo sapiens, 646.0); Ahcy (Mus musculus, 650.6); ahcy (Danio rerio, 657.5); ahcy (Xenopus tropicalis, 666.8); Ahcy13 (Drosophila melanogaster, 668.7); ahcy-1 (Caenorhabditis elegans, 643.7); HOG1 (Arabidopsis thaliana, 520.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:229826-231175:- | gene-YER043C_AKU4011 | rna-NM_001178934.3_AKU4011 | cds-NP_010961.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:194536-195885:+ | gene-YER043C_BG1 | rna-NM_001178934.3_BG1 | cds-NP_010961.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:238684-240033:- | gene-YER043C_Bruggeman | rna-NM_001178934.3_Bruggeman | cds-NP_010961.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:232797-234146:- | gene-YER043C_CAT1 | rna-NM_001178934.3_CAT1 | cds-NP_010961.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:229735-231084:- | gene-YER043C_CBS1585 | rna-NM_001178934.3_CBS1585 | cds-NP_010961.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:231684-233033:- | gene-YER043C_CBS436 | rna-NM_001178934.3_CBS436 | cds-NP_010961.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:229596-230945:- | gene-YER043C_CBS6412 | rna-NM_001178934.3_CBS6412 | cds-NP_010961.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:235206-236555:- | gene-YER043C_CBS6413 | rna-NM_001178934.3_CBS6413 | cds-NP_010961.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:233962-235311:- | gene-YER043C_CENPK1137D | rna-NM_001178934.3_CENPK1137D | cds-NP_010961.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:230430-231779:- | gene-YER043C_EthanolRed | rna-NM_001178934.3_EthanolRed | cds-NP_010961.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:230693-232042:- | gene-YER043C_FaliES1 | rna-NM_001178934.3_FaliES1 | cds-NP_010961.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000192.1:28461-29810:- | gene-YER043C_JAY291 | rna-NM_001178934.3_JAY291 | cds-NP_010961.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:234135-235484:- | gene-YER043C_MUCL30387 | rna-NM_001178934.3_MUCL30387 | cds-NP_010961.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:230351-231700:- | gene-YER043C_MUCL30388 | rna-NM_001178934.3_MUCL30388 | cds-NP_010961.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:228777-230126:- | gene-YER043C_MUCL39482 | rna-NM_001178934.3_MUCL39482 | cds-NP_010961.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:235853-237202:- | gene-YER043C_MUCL42920 | rna-NM_001178934.3_MUCL42920 | cds-NP_010961.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:235769-237118:- | gene-YER043C_NCIM3186 | rna-NM_001178934.3_NCIM3186 | cds-NP_010961.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:233839-235188:- | gene-YER043C_NCYC1407 | rna-NM_001178934.3_NCYC1407 | cds-NP_010961.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:244473-245822:- | gene-YER043C_PE2H3 | rna-NM_001178934.3_PE2H3 | cds-NP_010961.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:234414-235763:- | gene-YER043C_PE2H4 | rna-NM_001178934.3_PE2H4 | cds-NP_010961.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:235770-237119:- | gene-YER043C_S288C | rna-NM_001178934.3_S288C | cds-NP_010961.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:6570-7919:+ | gene-YER043C_SA1 | rna-NM_001178934.3_SA1 | cds-NP_010961.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:231465-232814:- | gene-YER043C_ThermosaccDry | rna-NM_001178934.3_ThermosaccDry | cds-NP_010961.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:230569-231918:- | gene-YER043C_VR1 | rna-NM_001178934.3_VR1 | cds-NP_010961.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:228675-230024:- | gene-YER043C_ZTW1 | rna-NM_001178934.3_ZTW1 | cds-NP_010961.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:232496-233845:- | gene-YER043C_Sparadoxus | rna-NM_001178934.3_Sparadoxus | cds-NP_010961.3_Sparadoxus | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |