Gene name: SAF1
Reference locus (S288C): YBR280C
Gene biotype: protein_coding
Description: Scf ubiquitin ligase complex subunit saf1; SCF-associated factor 1; F-Box protein involved in proteasome-dependent degradation of Aah1p; involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1
Top 10 interactors (score): HRT3 (0.97); CDC53 (0.967); AAH1 (0.951); SKP1 (0.945); YDR306C (0.909); YIL001W (0.866); ROY1 (0.76); YLR352W (0.712); PRB1 (0.71); MRX12 (0.696); UCC1 (0.692); SEN34 (0.69); YBL028C (0.675); DUG2 (0.651); MUM2 (0.65); SDS24 (0.611); RCY1 (0.576); RCM1 (0.573); RRT14 (0.573); COS111 (0.572)
Homologues (species, bitscore): HERC2 (Homo sapiens, 52.8); Herc2 (Mus musculus, 52.0); herc2 (Danio rerio, 50.4); herc2 (Xenopus tropicalis, 53.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:747084-748997:- | gene-YBR280C_AKU4011 | rna-NM_001178628.3_AKU4011 | cds-NP_009839.4_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:118079-119992:- | gene-YBR280C_BG1 | rna-NM_001178628.3_BG1 | cds-NP_009839.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:748218-750131:- | gene-YBR280C_Bruggeman | rna-NM_001178628.3_Bruggeman | cds-NP_009839.4_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:751943-753856:- | gene-YBR280C_CAT1 | rna-NM_001178628.3_CAT1 | cds-NP_009839.4_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:738650-740563:- | gene-YBR280C_CBS1585 | rna-NM_001178628.3_CBS1585 | cds-NP_009839.4_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:745066-746979:- | gene-YBR280C_CBS436 | rna-NM_001178628.3_CBS436 | cds-NP_009839.4_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:833265-835178:- | gene-YBR280C_CBS6412 | rna-NM_001178628.3_CBS6412 | cds-NP_009839.4_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:744698-746611:- | gene-YBR280C_CBS6413 | rna-NM_001178628.3_CBS6413 | cds-NP_009839.4_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:756684-758597:- | gene-YBR280C_CENPK1137D | rna-NM_001178628.3_CENPK1137D | cds-NP_009839.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:870119-872032:- | gene-YBR280C_EthanolRed | rna-NM_001178628.3_EthanolRed | cds-NP_009839.4_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:763466-765379:- | gene-YBR280C_FaliES1 | rna-NM_001178628.3_FaliES1 | cds-NP_009839.4_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:38710-40623:+ | gene-YBR280C_JAY291 | rna-NM_001178628.3_JAY291 | cds-NP_009839.4_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:750261-752174:- | gene-YBR280C_MUCL30387 | rna-NM_001178628.3_MUCL30387 | cds-NP_009839.4_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:767343-769256:- | gene-YBR280C_MUCL30388 | rna-NM_001178628.3_MUCL30388 | cds-NP_009839.4_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:736957-738870:- | gene-YBR280C_MUCL39482 | rna-NM_001178628.3_MUCL39482 | cds-NP_009839.4_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:746805-748718:- | gene-YBR280C_MUCL42920 | rna-NM_001178628.3_MUCL42920 | cds-NP_009839.4_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:762581-764494:- | gene-YBR280C_NCIM3186 | rna-NM_001178628.3_NCIM3186 | cds-NP_009839.4_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:738846-740759:- | gene-YBR280C_NCYC1407 | rna-NM_001178628.3_NCYC1407 | cds-NP_009839.4_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:761944-763857:- | gene-YBR280C_PE2H3 | rna-NM_001178628.3_PE2H3 | cds-NP_009839.4_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:759620-761533:- | gene-YBR280C_PE2H4 | rna-NM_001178628.3_PE2H4 | cds-NP_009839.4_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:762784-764697:- | gene-YBR280C_S288C | rna-NM_001178628.3_S288C | cds-NP_009839.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:117899-119812:- | gene-YBR280C_SA1 | rna-NM_001178628.3_SA1 | cds-NP_009839.4_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:762458-764371:- | gene-YBR280C_ThermosaccDry | rna-NM_001178628.3_ThermosaccDry | cds-NP_009839.4_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:742644-744557:- | gene-YBR280C_VR1 | rna-NM_001178628.3_VR1 | cds-NP_009839.4_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:735301-737214:- | gene-YBR280C_ZTW1 | rna-NM_001178628.3_ZTW1 | cds-NP_009839.4_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:779167-781086:- | gene-YBR280C_Sparadoxus | rna-NM_001178628.3_Sparadoxus | cds-NP_009839.4_Sparadoxus | 89.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |