Gene name: SAD1
Reference locus (S288C): YFR005C
Gene biotype: protein_coding
Description: U4/U6.U5 tri-snRNP-associated protein 2; Pre-mRNA-splicing factor SAD1; Conserved zinc-finger domain protein involved in pre-mRNA splicing; critical for splicing of nearly all intron-containing genes; required for assembly of U4 snRNA into the U4/U6 particle
Top 10 interactors (score): PRP3 (0.991); PRP31 (0.987); SNU114 (0.98); SNU66 (0.977); PRP8 (0.972); PRP28 (0.969); LSM8 (0.963); BRR2 (0.931); SME1 (0.911); UBP14 (0.9); PRP9 (0.898); LEA1 (0.881); PRP6 (0.877); RDS3 (0.847); LSM2 (0.832); SMX2 (0.823); PRP21 (0.818); LSM4 (0.812); PRP4 (0.809); HSH155 (0.794)
Homologues (species, bitscore): USP39 (Homo sapiens, 192.6); Usp39 (Mus musculus, 194.5); usp39 (Danio rerio, 193.7); usp39 (Xenopus tropicalis, 189.5); Usp39 (Drosophila melanogaster, 206.8); F09D1.1 (Caenorhabditis elegans, 184.1); AT4G22350 (Arabidopsis thaliana, 178.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:144973-146319:- | gene-YFR005C_AKU4011 | rna-NM_001179970.1_AKU4011 | cds-NP_116660.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000079.1:29868-31214:- | gene-YFR005C_BG1 | rna-NM_001179970.1_BG1 | cds-NP_116660.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:144539-145885:- | gene-YFR005C_Bruggeman | rna-NM_001179970.1_Bruggeman | cds-NP_116660.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:149704-151050:- | gene-YFR005C_CAT1 | rna-NM_001179970.1_CAT1 | cds-NP_116660.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:145798-147144:- | gene-YFR005C_CBS1585 | rna-NM_001179970.1_CBS1585 | cds-NP_116660.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:119645-120991:- | gene-YFR005C_CBS436 | rna-NM_001179970.1_CBS436 | cds-NP_116660.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:145539-146885:- | gene-YFR005C_CBS6412 | rna-NM_001179970.1_CBS6412 | cds-NP_116660.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:148049-149395:- | gene-YFR005C_CBS6413 | rna-NM_001179970.1_CBS6413 | cds-NP_116660.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:150662-152008:- | gene-YFR005C_CENPK1137D | rna-NM_001179970.1_CENPK1137D | cds-NP_116660.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:143959-145305:- | gene-YFR005C_EthanolRed | rna-NM_001179970.1_EthanolRed | cds-NP_116660.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:145606-146952:- | gene-YFR005C_FaliES1 | rna-NM_001179970.1_FaliES1 | cds-NP_116660.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000451.1:9713-11059:- | gene-YFR005C_JAY291 | rna-NM_001179970.1_JAY291 | cds-NP_116660.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:146170-147516:- | gene-YFR005C_MUCL30387 | rna-NM_001179970.1_MUCL30387 | cds-NP_116660.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:144146-145492:- | gene-YFR005C_MUCL30388 | rna-NM_001179970.1_MUCL30388 | cds-NP_116660.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:144242-145588:- | gene-YFR005C_MUCL39482 | rna-NM_001179970.1_MUCL39482 | cds-NP_116660.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:143505-144851:- | gene-YFR005C_MUCL42920 | rna-NM_001179970.1_MUCL42920 | cds-NP_116660.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:154526-155872:- | gene-YFR005C_NCIM3186 | rna-NM_001179970.1_NCIM3186 | cds-NP_116660.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:145257-146603:- | gene-YFR005C_NCYC1407 | rna-NM_001179970.1_NCYC1407 | cds-NP_116660.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:164323-165669:- | gene-YFR005C_PE2H3 | rna-NM_001179970.1_PE2H3 | cds-NP_116660.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:163871-165217:- | gene-YFR005C_PE2H4 | rna-NM_001179970.1_PE2H4 | cds-NP_116660.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:154527-155873:- | gene-YFR005C_S288C | rna-NM_001179970.1_S288C | cds-NP_116660.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:168353-169699:+ | gene-YFR005C_SA1 | rna-NM_001179970.1_SA1 | cds-NP_116660.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:144766-146112:- | gene-YFR005C_ThermosaccDry | rna-NM_001179970.1_ThermosaccDry | cds-NP_116660.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:159970-161316:- | gene-YFR005C_VR1 | rna-NM_001179970.1_VR1 | cds-NP_116660.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:75216-76562:- | gene-YFR005C_ZTW1 | rna-NM_001179970.1_ZTW1 | cds-NP_116660.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:168404-169750:- | gene-YFR005C_Sparadoxus | rna-NM_001179970.1_Sparadoxus | cds-NP_116660.1_Sparadoxus | 88.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |