Gene name: SAC3
Reference locus (S288C): YDR159W
Gene biotype: protein_coding
Description: Nuclear mRNA export protein SAC3; mRNA export factor; required for biogenesis of the small ribosomal subunit; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; similar to the human germinal center-associated nuclear protein (GANP)
Top 10 interactors (score): SUS1 (0.999); MEX67 (0.999); THP1 (0.999); CDC31 (0.999); SEM1 (0.997); YJR084W (0.997); THO2 (0.995); NUP1 (0.981); MTR2 (0.977); SUB2 (0.95); YRA1 (0.936); GLE2 (0.929); MCM3 (0.921); MLP1 (0.908); DBP5 (0.906); HPR1 (0.902); MLP2 (0.901); NUP60 (0.892); CDC39 (0.888); NSP1 (0.877)
Homologues (species, bitscore): MCM3AP (Homo sapiens, 149.8); Mcm3ap (Mus musculus, 159.5); mcm3ap (Danio rerio, 134.0); mcm3ap (Xenopus tropicalis, 140.2); xmas-2 (Drosophila melanogaster, 127.5); F20D12.2 (Caenorhabditis elegans, 119.4); SAC3B (Arabidopsis thaliana, 106.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:743198-747103:+ | gene-YDR159W_AKU4011 | rna-NM_001180466.3_AKU4011 | cds-NP_010443.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:379651-383556:- | gene-YDR159W_BG1 | rna-NM_001180466.3_BG1 | cds-NP_010443.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:774696-778601:+ | gene-YDR159W_Bruggeman | rna-NM_001180466.3_Bruggeman | cds-NP_010443.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:761983-765888:+ | gene-YDR159W_CAT1 | rna-NM_001180466.3_CAT1 | cds-NP_010443.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:733566-737471:+ | gene-YDR159W_CBS1585 | rna-NM_001180466.3_CBS1585 | cds-NP_010443.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:759736-763641:+ | gene-YDR159W_CBS436 | rna-NM_001180466.3_CBS436 | cds-NP_010443.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:729048-732953:+ | gene-YDR159W_CBS6412 | rna-NM_001180466.3_CBS6412 | cds-NP_010443.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:757464-761369:+ | gene-YDR159W_CBS6413 | rna-NM_001180466.3_CBS6413 | cds-NP_010443.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:772565-776470:+ | gene-YDR159W_CENPK1137D | rna-NM_001180466.3_CENPK1137D | cds-NP_010443.3_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:743025-746930:+ | gene-YDR159W_EthanolRed | rna-NM_001180466.3_EthanolRed | cds-NP_010443.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:751237-755142:+ | gene-YDR159W_FaliES1 | rna-NM_001180466.3_FaliES1 | cds-NP_010443.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000401.1:12152-16057:+ | gene-YDR159W_JAY291 | rna-NM_001180466.3_JAY291 | cds-NP_010443.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:759667-763572:+ | gene-YDR159W_MUCL30387 | rna-NM_001180466.3_MUCL30387 | cds-NP_010443.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:748584-752489:+ | gene-YDR159W_MUCL30388 | rna-NM_001180466.3_MUCL30388 | cds-NP_010443.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:734993-738898:+ | gene-YDR159W_MUCL39482 | rna-NM_001180466.3_MUCL39482 | cds-NP_010443.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:672818-676723:+ | gene-YDR159W_MUCL42920 | rna-NM_001180466.3_MUCL42920 | cds-NP_010443.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:771800-775705:+ | gene-YDR159W_NCIM3186 | rna-NM_001180466.3_NCIM3186 | cds-NP_010443.3_NCIM3186 | 79.5 | 88.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:734397-738302:+ | gene-YDR159W_NCYC1407 | rna-NM_001180466.3_NCYC1407 | cds-NP_010443.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:753586-757491:+ | gene-YDR159W_PE2H3 | rna-NM_001180466.3_PE2H3 | cds-NP_010443.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:752891-756796:+ | gene-YDR159W_PE2H4 | rna-NM_001180466.3_PE2H4 | cds-NP_010443.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:771877-775782:+ | gene-YDR159W_S288C | rna-NM_001180466.3_S288C | cds-NP_010443.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:119097-123002:+ | gene-YDR159W_SA1 | rna-NM_001180466.3_SA1 | cds-NP_010443.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:749372-753277:+ | gene-YDR159W_ThermosaccDry | rna-NM_001180466.3_ThermosaccDry | cds-NP_010443.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:764298-768203:+ | gene-YDR159W_VR1 | rna-NM_001180466.3_VR1 | cds-NP_010443.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:12122-16029:+ | gene-YDR159W_ZTW1 | rna-NM_001180466.3_ZTW1 | cds-NP_010443.3_ZTW1 | 99.3 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:755648-759565:+ | gene-YDR159W_Sparadoxus | rna-NM_001180466.3_Sparadoxus | cds-NP_010443.3_Sparadoxus | 85.8 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |