Gene name: SAC1
Reference locus (S288C): YKL212W
Gene biotype: protein_coding
Description: Phosphoinositide phosphatase SAC1; Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism
Top 10 interactors (score): STT4 (0.999); PIK1 (0.998); VPS74 (0.997); DPM1 (0.994); FAB1 (0.993); TSC3 (0.993); ORM1 (0.992); ORM2 (0.992); LCB1 (0.991); MSS4 (0.99); YMR1 (0.99); LCB2 (0.985); VPS34 (0.981); PIS1 (0.98); SCS2 (0.977); LSB6 (0.971); INP53 (0.969); SEC14 (0.964); INP52 (0.958); INP51 (0.957)
Homologues (species, bitscore): SACM1L (Homo sapiens, 360.5); Sacm1l (Mus musculus, 360.5); sacm1lb (Danio rerio, 378.6); sacm1l (Xenopus tropicalis, 305.8); Sac1 (Drosophila melanogaster, 361.3); sac-1 (Caenorhabditis elegans, 309.7); ATSAC1B (Arabidopsis thaliana, 282.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:20372-22243:+ | gene-YKL212W_AKU4011 | rna-NM_001179777.1_AKU4011 | cds-NP_012710.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000209.1:5387-7258:+ | gene-YKL212W_BG1 | rna-NM_001179777.1_BG1 | cds-NP_012710.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:38532-40403:+ | gene-YKL212W_Bruggeman | rna-NM_001179777.1_Bruggeman | cds-NP_012710.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:33174-35045:+ | gene-YKL212W_CAT1 | rna-NM_001179777.1_CAT1 | cds-NP_012710.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:32390-34261:+ | gene-YKL212W_CBS1585 | rna-NM_001179777.1_CBS1585 | cds-NP_012710.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:32076-33947:+ | gene-YKL212W_CBS436 | rna-NM_001179777.1_CBS436 | cds-NP_012710.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:18519-20390:+ | gene-YKL212W_CBS6412 | rna-NM_001179777.1_CBS6412 | cds-NP_012710.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:33019-34890:+ | gene-YKL212W_CBS6413 | rna-NM_001179777.1_CBS6413 | cds-NP_012710.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:34381-36252:+ | gene-YKL212W_CENPK1137D | rna-NM_001179777.1_CENPK1137D | cds-NP_012710.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:32504-34375:+ | gene-YKL212W_EthanolRed | rna-NM_001179777.1_EthanolRed | cds-NP_012710.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:32374-34245:+ | gene-YKL212W_FaliES1 | rna-NM_001179777.1_FaliES1 | cds-NP_012710.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:32008-33879:+ | gene-YKL212W_JAY291 | rna-NM_001179777.1_JAY291 | cds-NP_012710.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:40585-42456:+ | gene-YKL212W_MUCL30387 | rna-NM_001179777.1_MUCL30387 | cds-NP_012710.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:34914-36785:+ | gene-YKL212W_MUCL30388 | rna-NM_001179777.1_MUCL30388 | cds-NP_012710.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:32449-34320:+ | gene-YKL212W_MUCL39482 | rna-NM_001179777.1_MUCL39482 | cds-NP_012710.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:36221-38092:+ | gene-YKL212W_MUCL42920 | rna-NM_001179777.1_MUCL42920 | cds-NP_012710.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:34532-36403:+ | gene-YKL212W_NCIM3186 | rna-NM_001179777.1_NCIM3186 | cds-NP_012710.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:32473-34344:+ | gene-YKL212W_NCYC1407 | rna-NM_001179777.1_NCYC1407 | cds-NP_012710.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:40642-42513:+ | gene-YKL212W_PE2H3 | rna-NM_001179777.1_PE2H3 | cds-NP_012710.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:36840-38711:+ | gene-YKL212W_PE2H4 | rna-NM_001179777.1_PE2H4 | cds-NP_012710.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:34543-36414:+ | gene-YKL212W_S288C | rna-NM_001179777.1_S288C | cds-NP_012710.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000092.1:31466-33337:- | gene-YKL212W_SA1 | rna-NM_001179777.1_SA1 | cds-NP_012710.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:33098-34969:+ | gene-YKL212W_ThermosaccDry | rna-NM_001179777.1_ThermosaccDry | cds-NP_012710.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:32257-34128:+ | gene-YKL212W_VR1 | rna-NM_001179777.1_VR1 | cds-NP_012710.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:32065-33936:+ | gene-YKL212W_ZTW1 | rna-NM_001179777.1_ZTW1 | cds-NP_012710.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:40808-42679:+ | gene-YKL212W_Sparadoxus | rna-NM_001179777.1_Sparadoxus | cds-NP_012710.1_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |